Tyurina, Y.Y., Shrivastava, I., Tyurin, V.A., Mao, G., Dar, H.H., Watkins, S., Epperly, M., Bahar, I., Shvedova, A.A., Pitt, B., Wenzel, S.E., Mallampalli, R.K., Sadovsky, Y., Gabrilovich, D., Greenberger, J.S., Bayır, H., & Kagan, V.E. (2018). "Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions. Antioxid Redox Signal, 29(13), 1333-1358.Mary Ann Liebert. doi: 10.1089/ars.2017.7124.
Buland, J.R., Wasserloos, K.J., Tyurin, V.A., Tyurina, Y.Y., Amoscato, A.A., Mallampalli, R.K., Chen, B.B., Zhao, J., Zhao, Y., Ofori-Acquah, S., Kagan, V.E., & Pitt, B.R. (2016). Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity. Am J Physiol Lung Cell Mol Physiol, 311(2), L303-L316.American Physiological Society. doi: 10.1152/ajplung.00038.2016.
Stacy, S.L., Brink, L.L., Larkin, J.C., Sadovsky, Y., Goldstein, B.D., Pitt, B.R., & Talbott, E.O. (2015). Perinatal outcomes and unconventional natural gas operations in Southwest Pennsylvania. In Meliker, J. (Ed.). PLoS One, 10(6), e0126425.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0126425.
Andes, E. (2014). An examination of scenarios in dengue fever transmission with considerations in vector control, blood donation, and health communications in the United States. University of Pittsburgh.
Watson, K. (2014). Pharmaceuticals in the water: histological effects and intersex wildlife and sexual disruption. University of Pittsburgh.
Li, H.H., Li, J., Wasserloos, K.J., Wallace, C., Sullivan, M.G., Bauer, P.M., Stolz, D.B., Lee, J.S., Watkins, S.C., St Croix, C.M., Pitt, B.R., & Zhang, L.M. (2013). Caveolae-dependent and -independent uptake of albumin in cultured rodent pulmonary endothelial cells. In Zhao, Y.Y. (Ed.). PLoS One, 8(11), e81903.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0081903.
Cioffi, D.L., Wu, S., Chen, H., Alexeyev, M., St Croix, C.M., Pitt, B.R., Uhlig, S., & Stevens, T. (2012). Orai1 determines calcium selectivity of an endogenous TRPC heterotetramer channel. Circ Res, 110(11), 1435-1444.Wolters Kluwer. doi: 10.1161/CIRCRESAHA.112.269506.
Gorbunov, N.V., Atkins, J.L., Gurusamy, N., & Pitt, B.R. (2012). Iron-induced remodeling in cultured rat pulmonary artery endothelial cells. Biometals, 25(1), 203-217.Springer Nature. doi: 10.1007/s10534-011-9498-2.
Li, H.H., Li, Q., Liu, P., Liu, Y., Li, J., Wasserloos, K., Chao, W., You, M., Oury, T.D., Chhinder, S., Hackam, D.J., Billiar, T.R., Leikauf, G.D., Pitt, B.R., & Zhang, L.M. (2012). WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. Am J Respir Cell Mol Biol, 47(4), 528-535.American Thoracic Society. doi: 10.1165/rcmb.2012-0127OC.
Sparvero, L.J., Amoscato, A.A., Dixon, C.E., Long, J.B., Kochanek, P.M., Pitt, B.R., Bayir, H., & Kagan, V.E. (2012). Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations. Chem Phys Lipids, 165(5), 545-562.Elsevier. doi: 10.1016/j.chemphyslip.2012.06.001.
Thambiayya, K., Wasserloos, K., Kagan, V.E., Stoyanovsky, D., & Pitt, B.R. (2012). A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis. Am J Physiol Lung Cell Mol Physiol, 302(12), L1287-L1295.American Physiological Society. doi: 10.1152/ajplung.00385.2011.
Atkinson, J., Kapralov, A.A., Yanamala, N., Tyurina, Y.Y., Amoscato, A.A., Pearce, L., Peterson, J., Huang, Z., Jiang, J., Samhan-Arias, A.K., Maeda, A., Feng, W., Wasserloos, K., Belikova, N.A., Tyurin, V.A., Wang, H., Fletcher, J., Wang, Y., Vlasova, I.I., Klein-Seetharaman, J., Stoyanovsky, D.A., Bayîr, H., Pitt, B.R., Epperly, M.W., Greenberger, J.S., & Kagan, V.E. (2011). A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death. Nature communications, 2, 497.
Bernal, P.J., Bauer, E.M., Cao, R., Maniar, S., Mosher, M., Chen, J., Wang, Q.J., Glorioso, J.C., Pitt, B.R., Watkins, S.C., & St Croix, C.M. (2011). A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol, 300(6), L874-L886.American Physiological Society. doi: 10.1152/ajplung.00328.2010.
Cambal, L.K., Swanson, M.R., Yuan, Q., Weitz, A.C., Li, H.H., Pitt, B.R., Pearce, L.L., & Peterson, J. (2011). Acute, sublethal cyanide poisoning in mice is ameliorated by nitrite alone: complications arising from concomitant administration of nitrite and thiosulfate as an antidotal combination. Chem Res Toxicol, 24(7), 1104-1112.American Chemical Society (ACS). doi: 10.1021/tx2001042.
Li, H.H., Xu, J., Wasserloos, K.J., Li, J., Tyurina, Y.Y., Kagan, V.E., Wang, X., Chen, A.F., Liu, Z.Q., Stoyanovsky, D., Pitt, B.R., & Zhang, L.M. (2011). Cytoprotective effects of albumin, nitrosated or reduced, in cultured rat pulmonary vascular cells. Am J Physiol Lung Cell Mol Physiol, 300(4), L526-L533.American Physiological Society. doi: 10.1152/ajplung.00282.2010.
Thambiayya, K., Wasserloos, K.J., Huang, Z., Kagan, V.E., St Croix, C.M., & Pitt, B.R. (2011). LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol, 300(4), L624-L632.American Physiological Society. doi: 10.1152/ajplung.00376.2010.
Tyurina, Y.Y., Tyurin, V.A., Kapralova, V.I., Wasserloos, K., Mosher, M., Epperly, M.W., Greenberger, J.S., Pitt, B.R., & Kagan, V.E. (2011). Oxidative lipidomics of γ-radiation-induced lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Radiat Res, 175(5), 610-621.Radiation Research Society. doi: 10.1667/RR2297.1.
Gamble, C., Talbott, E., Youk, A., Holguin, F., Pitt, B., Silveira, L., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K.F., Erzurum, S., Israel, E., & Wenzel, S. (2010). Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program. J Allergy Clin Immunol, 126(6), 1149-56.e1.Elsevier. doi: 10.1016/j.jaci.2010.08.049.
John, E., Laskow, T.C., Buchser, W.J., Pitt, B.R., Basse, P.H., Butterfield, L.H., Kalinski, P., & Lotze, M.T. (2010). Zinc in innate and adaptive tumor immunity. J Transl Med, 8(1), 118.Springer Nature. doi: 10.1186/1479-5876-8-118.
Li, H., Cao, R., Wasserloos, K.J., Bernal, P., Liu, Z.Q., Pitt, B.R., & St Croix, C.M. (2010). Nitric oxide and zinc homeostasis in pulmonary endothelium. Ann N Y Acad Sci, 1203(1), 73-78.Wiley. doi: 10.1111/j.1749-6632.2010.05558.x.
Li, H., Su, X., Yan, X., Wasserloos, K., Chao, W., Kaynar, A.M., Liu, Z.Q., Leikauf, G.D., Pitt, B.R., & Zhang, L.M. (2010). Toll-like receptor 4-myeloid differentiation factor 88 signaling contributes to ventilator-induced lung injury in mice. Anesthesiology, 113(3), 619-629.Wolters Kluwer. doi: 10.1097/ALN.0b013e3181e89ab2.
Phillippi, J.A., Eskay, M.A., Kubala, A.A., Pitt, B.R., & Gleason, T.G. (2010). Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients. Ann Thorac Surg, 90(6), 1893-1898.Elsevier. doi: 10.1016/j.athoracsur.2010.07.069.
Polk, A.A., Maul, T.M., McKeel, D.T., Snyder, T.A., Lehocky, C.A., Pitt, B., Stolz, D.B., Federspiel, W.J., & Wagner, W.R. (2010). A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers. Biotechnol Bioeng, 106(3), 490-500.Wiley. doi: 10.1002/bit.22675.
Sparvero, L.J., Amoscato, A.A., Kochanek, P.M., Pitt, B.R., Kagan, V.E., & Bayir, H. (2010). Mass-spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury. J Neurochem, 115(6), 1322-1336.Wiley. doi: 10.1111/j.1471-4159.2010.07055.x.
Szczepaniak, W.S., Pitt, B.R., & McVerry, B.J. (2010). S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate. Am J Physiol Lung Cell Mol Physiol, 299(1), L137-L145.American Physiological Society. doi: 10.1152/ajplung.00233.2009.
Tyurina, Y.Y., Tyurin, V.A., Kaynar, A.M., Kapralova, V.I., Wasserloos, K., Li, J., Mosher, M., Wright, L., Wipf, P., Watkins, S., Pitt, B.R., & Kagan, V.E. (2010). Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am J Physiol Lung Cell Mol Physiol, 299(1), L73-L85.American Physiological Society. doi: 10.1152/ajplung.00035.2010.
Garner, A.L., St Croix, C.M., Pitt, B.R., Leikauf, G.D., Ando, S., & Koide, K. (2009). Specific fluorogenic probes for ozone in biological and atmospheric samples. Nat Chem, 1(4), 316-321.Springer Nature. doi: 10.1038/nchem.240.
Kagan, V.E., Bayir, H.A., Belikova, N.A., Kapralov, O., Tyurina, Y.Y., Tyurin, V.A., Jiang, J., Stoyanovsky, D.A., Wipf, P., Kochanek, P.M., Greenberger, J.S., Pitt, B., Shvedova, A.A., & Borisenko, G. (2009). Cytochrome c/cardiolipin relations in mitochondria: a kiss of death. Free Radic Biol Med, 46(11), 1439-1453.Elsevier. doi: 10.1016/j.freeradbiomed.2009.03.004.
Kagan, V.E., Wipf, P., Stoyanovsky, D., Greenberger, J.S., Borisenko, G., Belikova, N.A., Yanamala, N., Samhan Arias, A.K., Tungekar, M.A., Jiang, J., Tyurina, Y.Y., Ji, J., Klein-Seetharaman, J., Pitt, B.R., Shvedova, A.A., & Bayir, H. (2009). Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions. Adv Drug Deliv Rev, 61(14), 1375-1385.Elsevier. doi: 10.1016/j.addr.2009.06.008.
Li, J., Wilson, A., Gao, X., Kuruba, R., Liu, Y., Poloyac, S., Pitt, B., Xie, W., & Li, S. (2009). Coordinated regulation of dimethylarginine dimethylaminohydrolase-1 and cationic amino acid transporter-1 by farnesoid X receptor in mouse liver and kidney and its implication in the control of blood levels of asymmetric dimethylarginine. J Pharmacol Exp Ther, 331(1), 234-243.Elsevier. doi: 10.1124/jpet.109.153510.
Nemec, A.A., Leikauf, G.D., Pitt, B.R., Wasserloos, K.J., & Barchowsky, A. (2009). Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells. Am J Respir Cell Mol Biol, 41(1), 69-75.American Thoracic Society. doi: 10.1165/rcmb.2008-0409OC.
Tyurin, V.A., Tyurina, Y.Y., Jung, M.Y., Tungekar, M.A., Wasserloos, K.J., Bayir, H., Greenberger, J.S., Kochanek, P.M., Shvedova, A.A., Pitt, B., & Kagan, V.E. (2009). Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli. J Chromatogr B Analyt Technol Biomed Life Sci, 877(26), 2863-2872.Elsevier. doi: 10.1016/j.jchromb.2009.03.007.
Bernal, P.J., Leelavanichkul, K., Bauer, E., Cao, R., Wilson, A., Wasserloos, K.J., Watkins, S.C., Pitt, B.R., & St Croix, C.M. (2008). Nitric-oxide-mediated zinc release contributes to hypoxic regulation of pulmonary vascular tone. Circ Res, 102(12), 1575-1583.Wolters Kluwer. doi: 10.1161/CIRCRESAHA.108.171264.
Fattman, C.L., Gambelli, F., Hoyle, G., Pitt, B.R., & Ortiz, L.A. (2008). Epithelial expression of TIMP-1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice. Am J Physiol Lung Cell Mol Physiol, 294(3), L572-L581.American Physiological Society. doi: 10.1152/ajplung.00291.2007.
Kaynar, A.M., Houghton, A.M., Lum, E.H., Pitt, B.R., & Shapiro, S.D. (2008). Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury. Am J Respir Cell Mol Biol, 39(1), 53-60.American Thoracic Society. doi: 10.1165/rcmb.2007-0315OC.
Kleinschmidt, A.M., Nassiri, M., Stitt, M.S., Wasserloos, K., Watkins, S.C., Pitt, B.R., & Jahroudi, N. (2008). Sequences in intron 51 of the von Willebrand factor gene target promoter activation to a subset of lung endothelial cells in transgenic mice. J Biol Chem, 283(5), 2741-2750.Elsevier. doi: 10.1074/jbc.M705466200.
Li, J., Wilson, A., Kuruba, R., Zhang, Q., Gao, X., He, F., Zhang, L.M., Pitt, B.R., Xie, W., & Li, S. (2008). FXR-mediated regulation of eNOS expression in vascular endothelial cells. Cardiovasc Res, 77(1), 169-177.Oxford University Press (OUP). doi: 10.1093/cvr/cvm016.
Zhang, Q., He, F., Kuruba, R., Gao, X., Wilson, A., Li, J., Billiar, T.R., Pitt, B.R., Xie, W., & Li, S. (2008). FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells. Cardiovasc Res, 77(3), 560-569.Oxford University Press (OUP). doi: 10.1093/cvr/cvm068.
Tyurina, Y.Y., Basova, L.V., Konduru, N.V., Tyurin, V.A., Potapovich, A.I., Cai, P., Bayir, H., Stoyanovsky, D., Pitt, B.R., Shvedova, A.A., Fadeel, B., & Kagan, V.E. (2007). Nitrosative stress inhibits the aminophospholipid translocase resulting in phosphatidylserine externalization and macrophage engulfment: implications for the resolution of inflammation. J Biol Chem, 282(11), 8498-8509.Elsevier. doi: 10.1074/jbc.M606950200.
He, F., Li, J., Mu, Y., Kuruba, R., Ma, Z., Wilson, A., Alber, S., Jiang, Y., Stevens, T., Watkins, S., Pitt, B., Xie, W., & Li, S. (2006). Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells. Circ Res, 98(2), 192-199.Wolters Kluwer. doi: 10.1161/01.RES.0000200400.55539.85.
Matthay, M.A., Christman, J.W., Pitt, B.R., Schwiebert, L.M., Stevens, T., & Ware, L.B. (2006). Perspectives, translational research, and letters to the editor. Am J Physiol Lung Cell Mol Physiol, 290(4), L621.American Physiological Society. doi: 10.1152/ajplung.00003.2006.
Stitt, M.S., Wasserloos, K.J., Tang, X., Liu, X., Pitt, B.R., & St Croix, C.M. (2006). Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein. Vascul Pharmacol, 44(3), 149-155.Elsevier. doi: 10.1016/j.vph.2005.10.004.
Zhang, L.M., St Croix, C., Cao, R., Wasserloos, K., Watkins, S.C., Stevens, T., Li, S., Tyurin, V., Kagan, V.E., & Pitt, B.R. (2006). Cell-surface protein disulfide isomerase is required for transnitrosation of metallothionein by S-nitroso-albumin in intact rat pulmonary vascular endothelial cells. Exp Biol Med (Maywood), 231(9), 1507-1515.Frontiers. doi: 10.1177/153537020623100909.
Gandley, R.E., Tyurin, V.A., Huang, W., Arroyo, A., Daftary, A., Harger, G., Jiang, J., Pitt, B., Taylor, R.N., Hubel, C.A., & Kagan, V.E. (2005). S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma. Hypertension, 45(1), 21-27.Wolters Kluwer. doi: 10.1161/01.HYP.0000150158.42620.3e.
Ma, Z., Li, J., He, F., Wilson, A., Pitt, B., & Li, S. (2005). Cationic lipids enhance siRNA-mediated interferon response in mice. Biochem Biophys Res Commun, 330(3), 755-759.Elsevier. doi: 10.1016/j.bbrc.2005.03.041.
St Croix, C.M., Leelavaninchkul, K., Watkins, S.C., Kagan, V.E., & Pitt, B.R. (2005). Nitric oxide and zinc homeostasis in acute lung injury. Proc Am Thorac Soc, 2(3), 236-242.American Thoracic Society. doi: 10.1513/pats.200501-007AC.
St Croix, C.M., Pitt, B.R., & Watkins, S.C. (2005). The use of contemporary fluorescent imaging technologies in biomedical research. Medicine and Science, 10(1), 16-29.
St Croix, C.M., Stitt, M.S., Watkins, S.C., & Pitt, B.R. (2005). Fluorescence resonance energy transfer-based assays for the real-time detection of nitric oxide signaling. Methods Enzymol, 396, 317-326.Elsevier. doi: 10.1016/S0076-6879(05)96026-6.
Stoyanovsky, D.A., Tyurina, Y.Y., Tyurin, V.A., Anand, D., Mandavia, D.N., Gius, D., Ivanova, J., Pitt, B., Billiar, T.R., & Kagan, V.E. (2005). Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols. J Am Chem Soc, 127(45), 15815-15823.American Chemical Society (ACS). doi: 10.1021/ja0529135.
Wilson, A., He, F., Li, J., Ma, Z., Pitt, B., & Li, S. (2005). Targeted Delivery of Therapeutic Oligonucleotides to Pulmonary Circulation. In NON-VIRAL VECTORS FOR GENE THERAPY, SECOND EDITION: PART 2. 54, (pp. 21-41).Elsevier. doi: 10.1016/S0065-2660(05)54002-1.
Wilson, A., He, F., Li, J., Ma, Z., Pitt, B., & Li, S. (2005). Targeted delivery of therapeutic oligonucleotides to pulmonary circulation. Adv Genet, 54, 21-41. doi: 10.1016/S0065-2660(05)54002-1.
Wilson, A., Zhou, W., Champion, H.C., Alber, S., Tang, Z.L., Kennel, S., Watkins, S., Huang, L., Pitt, B., & Li, S. (2005). Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo. Mol Ther, 12(3), 510-518.Elsevier. doi: 10.1016/j.ymthe.2005.04.005.
Li, J., Ma, Z., Tang, Z.L., Stevens, T., Pitt, B., & Li, S. (2004). CpG DNA-mediated immune response in pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol, 287(3), L552-L558.American Physiological Society. doi: 10.1152/ajplung.00436.2003.
Ma, Z., Li, J., Yang, L., Mu, Y., Xie, W., Pitt, B., & Li, S. (2004). Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol, 286(4), L808-L816.American Physiological Society. doi: 10.1152/ajplung.00220.2003.
Pitt, B.R., & Ortiz, L.A. (2004). Stem cells in lung biology. Am J Physiol Lung Cell Mol Physiol, 286(4), L621-L623.American Physiological Society. doi: 10.1152/ajplung.00392.2003.
St Croix, C.M., Stitt, M.S., Leelavanichkul, K., Wasserloos, K.J., Pitt, B.R., & Watkins, S.C. (2004). Nitric oxide-induced modification of protein thiolate clusters as determined by spectral fluorescence resonance energy transfer in live endothelial cells. Free Radic Biol Med, 37(6), 785-792.Elsevier. doi: 10.1016/j.freeradbiomed.2004.06.004.
Tyurina, Y.Y., Tyurin, V.A., Zhao, Q., Djukic, M., Quinn, P.J., Pitt, B.R., & Kagan, V.E. (2004). Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis?. Biochem Biophys Res Commun, 324(3), 1059-1064.Elsevier. doi: 10.1016/j.bbrc.2004.09.102.
Lawler, C., Suk, W.A., Pitt, B.R., Croix, C.M.S., & Watkins, S.C. (2003). Multimodal optical imaging. Am J Physiol Lung Cell Mol Physiol, 285(2), L269-L280.American Physiological Society. doi: 10.1152/ajplung.00424.2002.
Zhang, J., Wilson, A., Alber, S., Ma, Z., Tang, Z.L., Satoh, E., Mazda, O., Watkins, S., Huang, L., Pitt, B., & Li, S. (2003). Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein-Barr virus-based episomal plasmid. Gene Ther, 10(9), 822-826.Springer Nature. doi: 10.1038/sj.gt.3301958.
Fabisiak, J.P., Borisenko, G.G., Liu, S.X., Tyurin, V.A., Pitt, B.R., & Kagan, V.E. (2002). Redox sensor function of metallothioneins. Methods Enzymol, 353, 268-281.Elsevier. doi: 10.1016/s0076-6879(02)53055-x.
Jiang, J., St Croix, C.M., Sussman, N., Zhao, Q., Pitt, B.R., & Kagan, V.E. (2002). Contribution of glutathione and metallothioneins to protection against copper toxicity and redox cycling: quantitative analysis using MT+/+ and MT-/- mouse lung fibroblast cells. Chem Res Toxicol, 15(8), 1080-1087.American Chemical Society (ACS). doi: 10.1021/tx020022u.
Ma, Z., Mi, Z., Wilson, A., Alber, S., Robbins, P.D., Watkins, S., Pitt, B., & Li, S. (2002). Redirecting adenovirus to pulmonary endothelium by cationic liposomes. Gene Ther, 9(3), 176-182.Springer Nature. doi: 10.1038/sj.gt.3301636.
Ma, Z., Zhang, J., Alber, S., Dileo, J., Negishi, Y., Stolz, D., Watkins, S., Huang, L., Pitt, B., & Li, S. (2002). Lipid-mediated delivery of oligonucleotide to pulmonary endothelium. Am J Respir Cell Mol Biol, 27(2), 151-159.American Thoracic Society. doi: 10.1165/ajrcmb.27.2.4653.
Pearce, L.L., Kanai, A.J., Birder, L.A., Pitt, B.R., & Peterson, J. (2002). The catabolic fate of nitric oxide: the nitric oxide oxidase and peroxynitrite reductase activities of cytochrome oxidase. J Biol Chem, 277(16), 13556-13562.Elsevier. doi: 10.1074/jbc.M109838200.
Pitt, B.R., & St Croix, C.M. (2002). Complex regulation of iNOS in lung. Am J Respir Cell Mol Biol, 26(1), 6-9.American Thoracic Society. doi: 10.1165/ajrcmb.26.1.f224.
St Croix, C.M., Wasserloos, K.J., Dineley, K.E., Reynolds, I.J., Levitan, E.S., & Pitt, B.R. (2002). Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein. Am J Physiol Lung Cell Mol Physiol, 282(2), L185-L192.American Physiological Society. doi: 10.1152/ajplung.00267.2001.
Tang, Z.L., Wasserloos, K.J., Liu, X., Stitt, M.S., Reynolds, I.J., Pitt, B.R., & St Croix, C.M. (2002). Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion. Mol Cell Biochem, 234-235(1-2), 211-217.Springer Nature. doi: 10.1023/a:1015930927407.
Wilson, A., Pitt, B., & Li, S. (2002). Complex roles of CpG in liposomal delivery of DNA and oligonucleotides. Biosci Rep, 22(2), 309-322.Portland Press. doi: 10.1023/a:1020146924504.
Zhou, W., Yuan, X., Wilson, A., Yang, L., Mokotoff, M., Pitt, B., & Li, S. (2002). Efficient intracellular delivery of oligonucleotides formulated in folate receptor-targeted lipid vesicles. Bioconjug Chem, 13(6), 1220-1225.American Chemical Society (ACS). doi: 10.1021/bc025569z.
Finder, J.D., Petrus, J.L., Hamilton, A., Villavicencio, R.T., Pitt, B.R., & Sebti, S.M. (2001). Signal transduction pathways of IL-1beta-mediated iNOS in pulmonary vascular smooth muscle cells. Am J Physiol Lung Cell Mol Physiol, 281(4), L816-L823.American Physiological Society. doi: 10.1152/ajplung.2001.281.4.L816.
Hauser, G.J., Wasserloos, K., Dayao, E.K., & Pitt, B.R. (2001). Effect of sodium arsenite on iNOS expression and vascular hyporeactivity associated with cecal ligation and puncture in the rat. Shock, 15(1), 73-76.Wolters Kluwer. doi: 10.1097/00024382-200115010-00012.
Liu, S., Kawai, K., Tyurin, V.A., Tyurina, Y.Y., Borisenko, G.G., Fabisiak, J.P., Quinn, P.J., Pitt, B.R., & Kagan, V.E. (2001). Nitric oxide-dependent pro-oxidant and pro-apoptotic effect of metallothioneins in HL-60 cells challenged with cupric nitrilotriacetate. Biochem J, 354(Pt 2), 397-406.Portland Press. doi: 10.1042/0264-6021:3540397.
Pearce, L.L., Epperly, M.W., Greenberger, J.S., Pitt, B.R., & Peterson, J. (2001). Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide. Nitric Oxide, 5(2), 128-136.Elsevier. doi: 10.1006/niox.2001.0338.
Pitt, B.R. (2001). CFTR trafficking and signaling in respiratory epithelium. Am J Physiol Lung Cell Mol Physiol, 281(1), L13-L15.American Physiological Society. doi: 10.1152/ajplung.2001.281.1.L13.
Tang, Z.L., Wasserloos, K., St Croix, C.M., & Pitt, B.R. (2001). Role of zinc in pulmonary endothelial cell response to oxidative stress. Am J Physiol Lung Cell Mol Physiol, 281(1), L243-L249.American Physiological Society. doi: 10.1152/ajplung.2001.281.1.L243.
Boota, A., Johnson, B., Lee, K.L., Blaskovich, M.A., Liu, S.X., Kagan, V.E., Hamilton, A., Pitt, B., Sebti, S.M., & Davies, P. (2000). Prenyltransferase inhibitors block superoxide production by pulmonary vascular smooth muscle. Am J Physiol Lung Cell Mol Physiol, 278(2), L329-L334.American Physiological Society. doi: 10.1152/ajplung.2000.278.2.L329.
Erukhimov, J.A., Tang, Z.L., Johnson, B.A., Donahoe, M.P., Razzack, J.A., Gibson, K.F., Lee, W.M., Wasserloos, K.J., Watkins, S.A., & Pitt, B.R. (2000). Actin-containing sera from patients with adult respiratory distress syndrome are toxic to sheep pulmonary endothelial cells. Am J Respir Crit Care Med, 162(1), 288-294.American Thoracic Society. doi: 10.1164/ajrccm.162.1.9806088.
Johnson, B.A., Pitt, B.R., & Davies, P. (2000). Pulmonary arterial smooth muscle cells modulate cytokine- and LPS-induced cytotoxicity in endothelial cells. Am J Physiol Lung Cell Mol Physiol, 278(3), L460-L468.American Physiological Society. doi: 10.1152/ajplung.2000.278.3.L460.
Kawai, K., Liu, S.X., Tyurin, V.A., Tyurina, Y.Y., Borisenko, G.G., Jiang, J.F., St Croix, C.M., Fabisiak, J.P., Pitt, B.R., & Kagan, V.E. (2000). Antioxidant and antiapoptotic function of metallothioneins in HL-60 cells challenged with copper nitrilotriacetate. Chem Res Toxicol, 13(12), 1275-1286.American Chemical Society (ACS). doi: 10.1021/tx000119l.
Li, S., Tan, Y., Viroonchatapan, E., Pitt, B.R., & Huang, L. (2000). Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody. Am J Physiol Lung Cell Mol Physiol, 278(3), L504-L511.American Physiological Society. doi: 10.1152/ajplung.2000.278.3.L504.
Liu, S.X., Fabisiak, J.P., Tyurin, V.A., Borisenko, G.G., Pitt, B.R., Lazo, J.S., & Kagan, V.E. (2000). Reconstitution of apo-superoxide dismutase by nitric oxide-induced copper transfer from metallothioneins. Chem Res Toxicol, 13(9), 922-931.American Chemical Society (ACS). doi: 10.1021/tx0000623.
Merker, M.P., Pitt, B.R., Choi, A.M., Hassoun, P.M., Dawson, C.A., & Fisher, A.B. (2000). Lung redox homeostasis: emerging concepts. Am J Physiol Lung Cell Mol Physiol, 279(3), L413-L417.American Physiological Society. doi: 10.1152/ajplung.2000.279.3.L413.
Pearce, L.L., Gandley, R.E., Han, W., Wasserloos, K., Stitt, M., Kanai, A.J., McLaughlin, M.K., Pitt, B.R., & Levitan, E.S. (2000). Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein. Proc Natl Acad Sci U S A, 97(1), 477-482.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.97.1.477.
Pearce, L.L., Wasserloos, K., St Croix, C.M., Gandley, R., Levitan, E.S., & Pitt, B.R. (2000). Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells. J Nutr, 130(5S Suppl), 1467S-1470S.Elsevier. doi: 10.1093/jn/130.5.1467S.
Schwarz, M.A., Zhang, F., Lane, J.E., Schachtner, S., Jin, Y., Deutsch, G., Starnes, V., & Pitt, B.R. (2000). Angiogenesis and morphogenesis of murine fetal distal lung in an allograft model. Am J Physiol Lung Cell Mol Physiol, 278(5), L1000-L1007.American Physiological Society. doi: 10.1152/ajplung.2000.278.5.L1000.
Villavicencio, R.T., Liu, S., Kibbe, M.R., Williams, D.L., Ganster, R.W., Dyer, K.F., Tweardy, D.J., Billiar, T.R., & Pitt, B.R. (2000). Induced nitric oxide inhibits IL-6-induced stat3 activation and type II acute phase mRNA expression. Shock, 13(6), 441-445.Wolters Kluwer. doi: 10.1097/00024382-200006000-00004.
Davidge, S.T., Pitt, B.R., McLaughlin, M.K., Roberts, J.M., & Johnson, B.A. (1999). Biphasic stimulation of prostacyclin by endogenous nitric oxide (NO) in endothelial cells transfected with inducible NO synthase. Gen Pharmacol, 33(5), 383-387.Elsevier. doi: 10.1016/s0306-3623(99)00033-6.
Fabisiak, J.P., Pearce, L.L., Borisenko, G.G., Tyhurina, Y.Y., Tyurin, V.A., Razzack, J., Lazo, J.S., Pitt, B.R., & Kagan, V.E. (1999). Bifunctional anti/prooxidant potential of metallothionenin: redox signaling of copper binding and release. Antioxid Redox Signal, 1(3), 349-364.Mary Ann Liebert. doi: 10.1089/ars.1999.1.3-349.
Fabisiak, J.P., Tyurin, V.A., Tyurina, Y.Y., Borisenko, G.G., Korotaeva, A., Pitt, B.R., Lazo, J.S., & Kagan, V.E. (1999). Redox regulation of copper-metallothionein. Arch Biochem Biophys, 363(1), 171-181.Elsevier. doi: 10.1006/abbi.1998.1077.
Li, S., Wu, S.P., Whitmore, M., Loeffert, E.J., Wang, L., Watkins, S.C., Pitt, B.R., & Huang, L. (1999). Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol, 276(5), L796-L804.American Physiological Society. doi: 10.1152/ajplung.1999.276.5.L796.
Pearce, L.L., Pitt, B.R., & Peterson, J. (1999). The peroxynitrite reductase activity of cytochrome c oxidase involves a two-electron redox reaction at the heme a(3)-Cu(B) site. J Biol Chem, 274(50), 35763-35767.Elsevier. doi: 10.1074/jbc.274.50.35763.
Tan, Y., Li, S., Pitt, B.R., & Huang, L. (1999). The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo. Hum Gene Ther, 10(13), 2153-2161.Mary Ann Liebert. doi: 10.1089/10430349950017149.
Ceneviva, G.D., Tzeng, E., Hoyt, D.G., Yee, E., Gallagher, A., Engelhardt, J.F., Kim, Y.M., Billiar, T.R., Watkins, S.A., & Pitt, B.R. (1998). Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells. Am J Physiol, 275(4), L717-L728.American Physiological Society. doi: 10.1152/ajplung.1998.275.4.L717.
Lazo, J.S., Kuo, S.M., Woo, E.S., & Pitt, B.R. (1998). The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs. Chem Biol Interact, 111-112, 255-262.Elsevier. doi: 10.1016/s0009-2797(97)00165-8.
Stark, W.W., Blaskovich, M.A., Johnson, B.A., Qian, Y., Vasudevan, A., Pitt, B., Hamilton, A.D., Sebti, S.M., & Davies, P. (1998). Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells. Am J Physiol, 275(1), L55-L63.American Physiological Society. doi: 10.1152/ajplung.1998.275.1.L55.
Hoyt, D.G., Rizzo, M., Gerritsen, M.E., Pitt, B.R., & Lazo, J.S. (1997). Integrin activation protects pulmonary endothelial cells from the genotoxic effects of bleomycin. Am J Physiol, 273(3 Pt 1), L612-L617.American Physiological Society. doi: 10.1152/ajplung.1997.273.3.L612.
Kondo, Y., Rusnak, J.M., Hoyt, D.G., Settineri, C.E., Pitt, B.R., & Lazo, J.S. (1997). Enhanced apoptosis in metallothionein null cells. Mol Pharmacol, 52(2), 195-201.Elsevier. doi: 10.1124/mol.52.2.195.
Pitt, B.R., Schwarz, M., Woo, E.S., Yee, E., Wasserloos, K., Tran, S., Weng, W., Mannix, R.J., Watkins, S.A., Tyurina, Y.Y., Tyurin, V.A., Kagan, V.E., & Lazo, J.S. (1997). Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury. Am J Physiol, 273(4), L856-L865.American Physiological Society. doi: 10.1152/ajplung.1997.273.4.L856.
Tzeng, E., Kim, Y.M., Pitt, B.R., Lizonova, A., Kovesdi, I., & Billiar, T.R. (1997). Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis. Surgery, 122(2), 255-263.Elsevier. doi: 10.1016/s0039-6060(97)90016-7.
Hauser, G.J., Dayao, E.K., Wasserloos, K., Pitt, B.R., & Wong, H.R. (1996). HSP induction inhibits iNOS mRNA expression and attenuates hypotension in endotoxin-challenged rats. Am J Physiol, 271(6 Pt 2), H2529-H2535.American Physiological Society. doi: 10.1152/ajpheart.1996.271.6.H2529.
Pitt, B.R., & Robbins, P.D. (1996). Retrovirus-mediated gene therapy to fetal lung. Mol Hum Reprod, 2(7), 467-469.Oxford University Press (OUP). doi: 10.1093/molehr/2.7.467.
Wong, H.R., Mannix, R.J., Rusnak, J.M., Boota, A., Zar, H., Watkins, S.C., Lazo, J.S., & Pitt, B.R. (1996). The heat-shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells. Am J Respir Cell Mol Biol, 15(6), 745-751.American Thoracic Society. doi: 10.1165/ajrcmb.15.6.8969269.
Pitt, B.R., Schwarz, M.A., Pilewski, J.M., Nakayama, D., Mueller, G.M., Robbins, P.D., Watkins, S.A., Albertine, K.H., & Bland, R.D. (1995). Retrovirus-mediated gene transfer in lungs of living fetal sheep. Gene Ther, 2(5), 344-350.
Tyurina, Y.Y., Tyurin, V.A., Yalowich, J.C., Quinn, P.J., Claycamp, H.G., Schor, N.F., Pitt, B.R., & Kagan, V.E. (1995). Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants. Toxicol Appl Pharmacol, 131(2), 277-288.Elsevier. doi: 10.1006/taap.1995.1070.
Wong, H.R., Finder, J.D., Wasserloos, K., & Pitt, B.R. (1995). Expression of iNOS in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response. Am J Physiol, 269(6 Pt 1), L843-L848.American Physiological Society. doi: 10.1152/ajplung.1995.269.6.L843.
Evans, R.R., Calmels, T.P., Pitt, B.R., Brookens, M.A., Johnson, C.S., Modzelewski, R.A., & Lazo, J.S. (1994). Gene therapy and endothelial cell targeting for cancer. Ann N Y Acad Sci, 716(1), 257-264.Wiley. doi: 10.1111/j.1749-6632.1994.tb21717.x.
Nakayama, D.K., Geller, D.A., Di Silvio, M., Bloomgarden, G., Davies, P., Pitt, B.R., Hatakeyama, K., Kagamiyama, H., Simmons, R.L., & Billiar, T.R. (1994). Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle. Am J Physiol, 266(4 Pt 1), L455-L460.American Physiological Society. doi: 10.1152/ajplung.1994.266.4.L455.
Schwarz, M.A., Lazo, J.S., Yalowich, J.C., Reynolds, I., Kagan, V.E., Tyurin, V., Kim, Y.M., Watkins, S.C., & Pitt, B.R. (1994). Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity. J Biol Chem, 269(21), 15238-15243.Elsevier. doi: 10.1016/s0021-9258(17)36597-3.
Weng, W.L., Lazo, J.S., Gillis, C.N., & Pitt, B.R. (1990). Disposition of radioiodinated benzylguanidines in perfused rabbit lung: pharmacokinetics and effect of an organo-gold complexed antineoplastic agent. J Pharmacol Exp Ther, 255(1), 59-65.Elsevier. doi: 10.1016/s0022-3565(25)12787-0.
Yeates, D.B., Spektor, D.M., Leikauf, G.D., & Pitt, B.R. (1981). Effects of drugs on mucociliary transport in the trachea and bronchial airways. Chest, 80(6 Suppl), 870-873.Elsevier. doi: 10.1378/chest.80.6.870.