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Bourne, D.A., James, I., Wang, S., Bliley, J., Grahovac, T., Mitchell, R.T., Brown, S.A., Ambrosio, F., Ho, J., Lannau, B., Kemp, P.D., Gusenoff, J., Rubin, J.P., Gusenoff, J. (2021). Treatment of burn contractures with allogeneic human dermal fibroblasts improves Vancouver scar scale: A phase I/II trial. J Plast Reconstr Aesthet Surg, 74(12), 3443-3476.Elsevier. doi: 10.1016/j.bjps.2021.08.018.
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Kakar, R.S., Pastor, J.V., Moe, O.W., Ambrosio, F., Castaldi, D., & Sanders, L.H. (2021). Peripheral Klotho and Parkinson's Disease. Mov Disord, 36(5), 1274-1276.Wiley. doi: 10.1002/mds.28530.
Anguiano, T., Sahu, A., Qian, B., Tang, W.Y., Ambrosio, F., & Barchowsky, A. (2020). Arsenic Directs Stem Cell Fate by Imparting Notch Signaling Into the Extracellular Matrix Niche. Toxicol Sci, 177(2), 494-505.Oxford University Press (OUP). doi: 10.1093/toxsci/kfaa106.
Cheikhi, A., Anguiano, T., Lasak, J., Qian, B., Sahu, A., Mimiya, H., Cohen, C.C., Wipf, P., Ambrosio, F., & Barchowsky, A. (2020). Arsenic Stimulates Myoblast Mitochondrial Epidermal Growth Factor Receptor to Impair Myogenesis. Toxicol Sci, 176(1), 162-174.Oxford University Press (OUP). doi: 10.1093/toxsci/kfaa031.
Sachdev, U., Ferrari, R., Cui, X., Pius, A., Sahu, A., Reynolds, M., Liao, H., Sun, P., Shinde, S., Ambrosio, F., Shiva, S., Loughran, P., & Scott, M. (2020). Caspase1/11 signaling affects muscle regeneration and recovery following ischemia, and can be modulated by chloroquine. Mol Med, 26(1), 69.Springer Nature. doi: 10.1186/s10020-020-00190-2.
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Cheikhi, A., Barchowsky, A., Sahu, A., Shinde, S.N., Pius, A., Clemens, Z.J., Li, H., Kennedy, C.A., Hoeck, J.D., Franti, M., & Ambrosio, F. (2019). Klotho: An Elephant in Aging Research. J Gerontol A Biol Sci Med Sci, 74(7), 1031-1042.Oxford University Press (OUP). doi: 10.1093/gerona/glz061.
Cheikhi, A., Barchowsky, A., Sahu, A., Shinde, S.N., Pius, A., Clemens, Z.J., Li, H., Kennedy, C.A., Hoeck, J.D., Franti, M., & Ambrosio, F. (2019). Klotho: An Elephant in Aging Research. J Gerontol A Biol Sci Med Sci, 74(7), 1031-1042.Oxford University Press (OUP). doi: 10.1093/gerona/glz061.
Cheikhi, A., Wallace, C., St Croix, C., Cohen, C., Tang, W.Y., Wipf, P., Benos, P.V., Ambrosio, F., & Barchowsky, A. (2019). Mitochondria are a substrate of cellular memory. Free Radic Biol Med, 130, 528-541.Elsevier. doi: 10.1016/j.freeradbiomed.2018.11.028.
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Hartman, R., Patil, P., Tisherman, R., St Croix, C., Niedernhofer, L.J., Robbins, P.D., Ambrosio, F., Van Houten, B., Sowa, G., & Vo, N. (2018). Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics. Eur Cell Mater, 36, 171-183.European Cells and Materials. doi: 10.22203/eCM.v036a13.
Rando, T.A., & Ambrosio, F. (2018). Regenerative Rehabilitation: Applied Biophysics Meets Stem Cell Therapeutics. Cell Stem Cell, 22(3), 306-309.Elsevier. doi: 10.1016/j.stem.2018.02.003.
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Sahu, A., Mamiya, H., Shinde, S.N., Cheikhi, A., Winter, L.L., Vo, N.V., Stolz, D., Roginskaya, V., Tang, W.Y., St Croix, C., Sanders, L.H., Franti, M., Van Houten, B., Rando, T.A., Barchowsky, A., & Ambrosio, F. (2018). Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration. Nat Commun, 9(1), 4859.Springer Nature. doi: 10.1038/s41467-018-07253-3.
Dalise, S., Cavalli, L., Ghuman, H., Wahlberg, B., Gerwig, M., Chisari, C., Ambrosio, F., & Modo, M. (2017). Biological effects of dosing aerobic exercise and neuromuscular electrical stimulation in rats. Sci Rep, 7(1), 10830.Springer Nature. doi: 10.1038/s41598-017-11260-7.
Lai, S., Panarese, A., Lawrence, R., Boninger, M.L., Micera, S., & Ambrosio, F. (2017). A Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery after Injury. Med Sci Sports Exerc, 49(4), 840-847.Wolters Kluwer. doi: 10.1249/MSS.0000000000001160.
Moritz, C.T., & Ambrosio, F. (2017). Regenerative Rehabilitation: Combining Stem Cell Therapies and Activity-Dependent Stimulation. Pediatr Phys Ther, 29 Suppl 3(Suppl 3 IV STEP 2016 CONFERENCE PROCEEDINGS), S10-S15.Wolters Kluwer. doi: 10.1097/PEP.0000000000000378.
Stearns-Reider, K.M., D'Amore, A., Beezhold, K., Rothrauff, B., Cavalli, L., Wagner, W.R., Vorp, D.A., Tsamis, A., Shinde, S., Zhang, C., Barchowsky, A., Rando, T.A., Tuan, R.S., & Ambrosio, F. (2017). Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. Aging Cell, 16(3), 518-528.Wiley. doi: 10.1111/acel.12578.
Ambrosio, F., & Kleim, J.A. (2016). Regenerative Rehabilitation and Genomics: Frontiers in Clinical Practice. Phys Ther, 96(4), 430-432.Oxford University Press (OUP). doi: 10.2522/ptj.2016.96.4.430.
Badylak, S.F., Dziki, J.L., Sicari, B.M., Ambrosio, F., & Boninger, M.L. (2016). Mechanisms by which acellular biologic scaffolds promote functional skeletal muscle restoration. Biomaterials, 103, 128-136.Elsevier. doi: 10.1016/j.biomaterials.2016.06.047.
Han, N., Yabroudi, M.A., Stearns-Reider, K., Helkowski, W., Sicari, B.M., Rubin, J.P., Badylak, S.F., Boninger, M.L., & Ambrosio, F. (2016). Electrodiagnostic Evaluation of Individuals Implanted With Extracellular Matrix for the Treatment of Volumetric Muscle Injury: Case Series. Phys Ther, 96(4), 540-549.Oxford University Press (OUP). doi: 10.2522/ptj.20150133.
Ross, H.H., Ambrosio, F., Trumbower, R.D., Reier, P.J., Behrman, A.L., & Wolf, S.L. (2016). Neural Stem Cell Therapy and Rehabilitation in the Central Nervous System: Emerging Partnerships. Phys Ther, 96(5), 734-742.Oxford University Press (OUP). doi: 10.2522/ptj.20150063.
Zhang, C., Ferrari, R., Beezhold, K., Stearns-Reider, K., D'Amore, A., Haschak, M., Stolz, D., Robbins, P.D., Barchowsky, A., & Ambrosio, F. (2016). Arsenic Promotes NF-Κb-Mediated Fibroblast Dysfunction and Matrix Remodeling to Impair Muscle Stem Cell Function. Stem Cells, 34(3), 732-742.Oxford University Press (OUP). doi: 10.1002/stem.2232.
Ambrosio, F., Brown, E., Stolz, D., Ferrari, R., Goodpaster, B., Deasy, B., Distefano, G., Roperti, A., Cheikhi, A., Garciafigueroa, Y., & Barchowsky, A. (2014). Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med, 74, 64-73.Elsevier. doi: 10.1016/j.freeradbiomed.2014.06.012.
Avin, K.G., Coen, P.M., Huang, W., Stolz, D.B., Sowa, G.A., Dubé, J.J., Goodpaster, B.H., O'Doherty, R.M., & Ambrosio, F. (2014). Skeletal muscle as a regulator of the longevity protein, Klotho. Front Physiol, 5, 189.Frontiers. doi: 10.3389/fphys.2014.00189.
Dalise, S., Ambrosio, F., & Modo, M. (2014). Adaptive plasticity and recovery in preclinical models of stroke. ARCHIVES ITALIENNES DE BIOLOGIE, 152(4), 190-215.Pisa University Press. doi: 10.12871/00039829201442.
Dalise, S., Ambrosio, F., & Modo, M. (2014). Brain plasticity and recovery in preclinical models of stroke. Arch Ital Biol, 152(4), 190-215. doi: 10.12871/00039829201442.
Gentile, N.E., Stearns, K.M., Brown, E.H.P., Rubin, J.P., Boninger, M.L., Dearth, C.L., Ambrosio, F., & Badylak, S.F. (2014). Targeted rehabilitation after extracellular matrix scaffold transplantation for the treatment of volumetric muscle loss. Am J Phys Med Rehabil, 93(11 Suppl 3), S79-S87.Wolters Kluwer. doi: 10.1097/PHM.0000000000000145.
Sicari, B.M., Rubin, J.P., Dearth, C.L., Wolf, M.T., Ambrosio, F., Boninger, M., Turner, N.J., Weber, D.J., Simpson, T.W., Wyse, A., Brown, E.H.P., Dziki, J.L., Fisher, L.E., Brown, S., & Badylak, S.F. (2014). An Acellular Biologic Scaffold Promotes Skeletal Muscle Formation in Mice and Humans with Volumetric Muscle Loss. SCIENCE TRANSLATIONAL MEDICINE, 6(234), 234ra58.American Association for the Advancement of Science (AAAS). doi: 10.1126/scitranslmed.3008085.
Ambrosio, F., Boninger, M.L., Brubaker, C.E., Delitto, A., Wagner, W.R., Shields, R.K., Wolf, S.L., & Rando, T.A. (2013). Guest editorial: emergent themes from second annual symposium on regenerative rehabilitation, Pittsburgh, Pennsylvania. J Rehabil Res Dev, 50(3), vii-xiv.Journal of Rehabilitation Research & Development. doi: 10.1682/jrrd.2013.04.0081.
Distefano, G., Ferrari, R.J., Weiss, C., Deasy, B.M., Boninger, M.L., Fitzgerald, G.K., Huard, J., & Ambrosio, F. (2013). Neuromuscular electrical stimulation as a method to maximize the beneficial effects of muscle stem cells transplanted into dystrophic skeletal muscle. In Musaro, A. (Ed.). PLoS One, 8(3), e54922.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0054922.
Garciafigueroa, D.Y., Klei, L.R., Ambrosio, F., & Barchowsky, A. (2013). Arsenic-stimulated lipolysis and adipose remodeling is mediated by G-protein-coupled receptors. Toxicol Sci, 134(2), 335-344.Oxford University Press (OUP). doi: 10.1093/toxsci/kft108.
Kobayashi, T., Uehara, K., Ota, S., Tobita, K., Ambrosio, F., Cummins, J.H., Terada, S., Fu, F.H., & Huard, J. (2013). The timing of administration of a clinically relevant dose of losartan influences the healing process after contusion induced muscle injury. J Appl Physiol (1985), 114(2), 262-273.American Physiological Society. doi: 10.1152/japplphysiol.00140.2011.
Modo, M., Ambrosio, F., Friedlander, R.M., Badylak, S.F., & Wechsler, L.R. (2013). Bioengineering solutions for neural repair and recovery in stroke. Curr Opin Neurol, 26(6), 626-631.Wolters Kluwer. doi: 10.1097/WCO.0000000000000031.
Ambrosio, F., Fitzgerald, G.K., Ferrari, R., Distefano, G., & Carvell, G. (2012). A murine model of muscle training by neuromuscular electrical stimulation. J Vis Exp, (63), e3914.MyJove. doi: 10.3791/3914.
Childers, M.K., Markert, C., Atala, A., Cann, J., Christ, G., Furth, M., & Ambrosio, F. (2012). Regenerative medicine: Implications in rehabilitation. In DeLisa's Physical Medicine and Rehabilitation: Principles and Practice: Fifth Edition. 2-2, (pp. 2173-2186).
Ambrosio, F., Tarabishy, A., Kadi, F., Brown, E.H.P., & Sowa, G. (2011). Biological basis of exercise-based treatments for musculoskeletal conditions. PM R, 3(6 Suppl 1), S59-S63.Wiley. doi: 10.1016/j.pmrj.2011.05.001.
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Markert, C.D., Ambrosio, F., Call, J.A., & Grange, R.W. (2011). Exercise and Duchenne muscular dystrophy: toward evidence-based exercise prescription. Muscle Nerve, 43(4), 464-478.Wiley. doi: 10.1002/mus.21987.
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Ambrosio, F., Ferrari, R.J., Fitzgerald, G.K., Carvell, G., Boninger, M.L., & Huard, J. (2009). Functional overloading of dystrophic mice enhances muscle-derived stem cell contribution to muscle contractile capacity. Arch Phys Med Rehabil, 90(1), 66-73.Elsevier. doi: 10.1016/j.apmr.2008.06.035.
Ambrosio, F., Kadi, F., Lexell, J., Fitzgerald, G.K., Boninger, M.L., & Huard, J. (2009). The effect of muscle loading on skeletal muscle regenerative potential: an update of current research findings relating to aging and neuromuscular pathology. Am J Phys Med Rehabil, 88(2), 145-155.Wolters Kluwer. doi: 10.1097/PHM.0b013e3181951fc5.
Deasy, B.M., Feduska, J.M., Payne, T.R., Li, Y., Ambrosio, F., & Huard, J. (2009). Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle. Mol Ther, 17(10), 1788-1798.Elsevier. doi: 10.1038/mt.2009.136.
Markert, C.D., Atala, A., Cann, J.K., Christ, G., Furth, M., Ambrosio, F., & Childers, M.K. (2009). Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy. PM R, 1(6), 547-559.Wiley. doi: 10.1016/j.pmrj.2009.02.013.
Nozaki, M., Li, Y., Zhu, J., Ambrosio, F., Uehara, K., Fu, F.H., & Huard, J. (2008). Improved muscle healing after contusion injury by the inhibitory effect of suramin on myostatin, a negative regulator of muscle growth. Am J Sports Med, 36(12), 2354-2362.SAGE Publications. doi: 10.1177/0363546508322886.
Ambrosio, F., Boninger, M.L., Fitzgerald, S.G., Hubbard, S.L., Schwid, S.R., & Cooper, R.A. (2007). Comparison of mobility device delivery within Department of Veterans Affairs for individuals with multiple sclerosis versus spinal cord injury. J Rehabil Res Dev, 44(5), 693-701.Journal of Rehabilitation Research & Development. doi: 10.1682/jrrd.2006.02.0016.
Zhu, J., Li, Y., Shen, W., Qiao, C., Ambrosio, F., Lavasani, M., Nozaki, M., Branca, M.F., & Huard, J. (2007). Relationships between transforming growth factor-beta1, myostatin, and decorin: implications for skeletal muscle fibrosis. J Biol Chem, 282(35), 25852-25863.Elsevier. doi: 10.1074/jbc.M704146200.
Ambrosio, F., Boninger, M.L., Souza, A.L., Fitzgerald, S.G., Koontz, A.M., & Cooper, R.A. (2005). Biomechanics and strength of manual wheelchair users. J Spinal Cord Med, 28(5), 407-414.Taylor & Francis. doi: 10.1080/10790268.2005.11753840.
Souza, A.L., Boninger, M.L., Fitzgerald, S.G., Shimada, S.D., Cooper, R.A., & Ambrosio, F. (2005). Upper limb strength in individuals with spinal cord injury who use manual wheelchairs. J Spinal Cord Med, 28(1), 26-32.Taylor & Francis. doi: 10.1080/10790268.2005.11753795.
Koontz, A.M., Cooper, R.A., Arva, J., Buning, M.E., Souza, A.L., & Ambrosio, F. (2004). Strength and Disability. In Muscle Strength, Kumar, S. (Ed.). (pp. 485-518).CRC Press LLC.
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Fay, B.T., Boninger, M.L., Ambrosio, F., & Cooper, R.A. (2003). Aspects of Fatigue in Multiple Sclerosis during Manual Wheelchair Propulsion. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2, (pp. 1606-1608).