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Borgini, M., Wieteska, Ł., Hinck, C.S., Krzysiak, T., Hinck, A.P., & Wipf, P. (2023). Synthesis of 13C-methyl-labeled amino acids and their incorporation into proteins in mammalian cells. Org Biomol Chem, 21(46), 9216-9229.Royal Society of Chemistry (RSC). doi: 10.1039/d3ob01320k.
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Chen, P.P., Wipf, P., & Houk, K.N. (2022). How mono- and diphosphine ligands alter regioselectivity of the Rh-catalyzed annulative cleavage of bicyclo[1.1.0]butanes. Nat Commun, 13(1), 7292.Springer Nature. doi: 10.1038/s41467-022-34837-x.
Ueda, H., Wipf, P., & Nakamura, H. (2022). Synthesis of sp3-rich chiral bicyclo[3.3.1]nonanes for chemical space expansion and study of biological activities. Bioorg Med Chem, 54, 116561.Elsevier. doi: 10.1016/j.bmc.2021.116561.
Borgini, M., Mondal, P., Liu, R., & Wipf, P. (2021). Chemical modulation of Kv7 potassium channels. RSC Med Chem, 12(4), 483-537.Royal Society of Chemistry (RSC). doi: 10.1039/d0md00328j.
Rastelli, E.J., Sannino, S., Hart, D.J., Sharlow, E.R., Lazo, J.S., Brodsky, J.L., & Wipf, P. (2021). Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway. Bioorg Med Chem Lett, 46, 128167.Elsevier. doi: 10.1016/j.bmcl.2021.128167.
Tasker, N.R., & Wipf, P. (2021). Biosynthesis, total synthesis, and biological profiles of Ergot alkaloids. In The Alkaloids: Chemistry and Biology. 85, (pp. 1-112).Elsevier. doi: 10.1016/bs.alkal.2020.08.001.
Yang, Z., Wang, D., Johnson, J.K., Pascal, L.E., Takubo, K., Avula, R., Chakka, A.B., Zhou, J., Chen, W., Zhong, M., Song, Q., Ding, H., Wu, Z., Chandran, U.R., Maskrey, T.S., Nelson, J.B., Wipf, P., & Wang, Z. (2020). A Novel Small Molecule Targets Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer. Mol Cancer Ther, 19(1), 75-88.American Association for Cancer Research (AACR). doi: 10.1158/1535-7163.MCT-19-0489.
Cheikhi, A., Wallace, C., St Croix, C., Cohen, C., Tang, W.Y., Wipf, P., Benos, P.V., Ambrosio, F., & Barchowsky, A. (2019). Mitochondria are a substrate of cellular memory. Free Radic Biol Med, 130, 528-541.Elsevier. doi: 10.1016/j.freeradbiomed.2018.11.028.
Tasker, N.R., Rastelli, E.J., Blanco, I.K., Burnett, J.C., Sharlow, E.R., Lazo, J.S., & Wipf, P. (2019). In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors. Org Biomol Chem, 17(9), 2448-2466.Royal Society of Chemistry (RSC). doi: 10.1039/c9ob00025a.
Tasker, N.R., Rastelli, E.J., Burnett, J.C., Sharlow, E.R., Lazo, J.S., & Wipf, P. (2019). Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorg Med Chem Lett, 29(16), 2008-2015.Elsevier. doi: 10.1016/j.bmcl.2019.06.048.
Saydmohammed, M., Vollmer, L.L., Onuoha, E.O., Maskrey, T.S., Gibson, G., Watkins, S.C., Wipf, P., Vogt, A., & Tsang, M. (2018). A High-Content Screen Reveals New Small-Molecule Enhancers of Ras/Mapk Signaling as Probes for Zebrafish Heart Development. Molecules, 23(7), 1691.MDPI. doi: 10.3390/molecules23071691.
Jang, S., Lewis, T.S., Powers, C., Khuchua, Z., Baines, C.P., Wipf, P., & Javadov, S. (2017). Elucidating Mitochondrial Electron Transport Chain Supercomplexes in the Heart During Ischemia-Reperfusion. Antioxid Redox Signal, 27(1), 57-69.Mary Ann Liebert. doi: 10.1089/ars.2016.6635.
Xu, J., & Wipf, P. (2017). Indole synthesis by palladium-catalyzed tandem allylic isomerization - furan Diels-Alder reaction. Org Biomol Chem, 15(34), 7093-7096.Royal Society of Chemistry (RSC). doi: 10.1039/c7ob01654a.
Kumar, M., Reed, N., Liu, R., Aizenman, E., Wipf, P., & Tzounopoulos, T. (2016). Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators. Mol Pharmacol, 89(6), 667-677.Elsevier. doi: 10.1124/mol.115.103200.
Salamoun, J.M., McQueeney, K.E., Patil, K., Geib, S.J., Sharlow, E.R., Lazo, J.S., & Wipf, P. (2016). Photooxygenation of an amino-thienopyridone yields a more potent PTP4A3 inhibitor. Org Biomol Chem, 14(27), 6398-6402.Royal Society of Chemistry (RSC). doi: 10.1039/c6ob00946h.
George Rosenker, K.M., Paquette, W.D., Johnston, P.A., Sharlow, E.R., Vogt, A., Bakan, A., Lazo, J.S., & Wipf, P. (2015). Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B. Bioorg Med Chem, 23(12), 2810-2818.Elsevier. doi: 10.1016/j.bmc.2015.01.043.
Greenberger, J., Kagan, V., Bayir, H., Wipf, P., & Epperly, M. (2015). Antioxidant Approaches to Management of Ionizing Irradiation Injury. Antioxidants (Basel), 4(1), 82-101.MDPI. doi: 10.3390/antiox4010082.
Ma, J., Lim, C., Sacher, J.R., Van Houten, B., Qian, W., & Wipf, P. (2015). Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells. Bioorg Med Chem Lett, 25(21), 4828-4833.Elsevier. doi: 10.1016/j.bmcl.2015.06.073.
Qian, W., Salamoun, J., Wang, J., Roginskaya, V., Van Houten, B., & Wipf, P. (2015). The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak. Bioorg Med Chem Lett, 25(4), 856-863.Elsevier. doi: 10.1016/j.bmcl.2014.12.072.
Tandon, M., Salamoun, J.M., Carder, E.J., Farber, E., Xu, S., Deng, F., Tang, H., Wipf, P., & Wang, Q.J. (2015). SD-208, a novel protein kinase D inhibitor, blocks prostate cancer cell proliferation and tumor growth in vivo by inducing G2/M cell cycle arrest. In Languino, L.R. (Ed.). PLoS One, 10(3), e0119346.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0119346.
Adam, C., Baeurle, A., Brodsky, J.L., Wipf, P., Schrama, D., Becker, J.C., & Houben, R. (2014). The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma. In Sherman, M. (Ed.). PLoS One, 9(4), e92041.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0092041.
Greenberger, J.S., Berhane, H., Shinde, A., Rhieu, B.H., Bernard, M., Wipf, P., Skoda, E.M., & Epperly, M.W. (2014). Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors. Front Oncol, 4, 24.Frontiers. doi: 10.3389/fonc.2014.00024.
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Cao, L., Maciejewski, J.P., Elzner, S., Amantini, D., & Wipf, P. (2012). Synthesis of 1,2,4-triazines and the triazinoisoquinolinedione DEF ring system of noelaquinone. Org Biomol Chem, 10(30), 5811-5814.Royal Society of Chemistry (RSC). doi: 10.1039/c2ob25353d.
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Liu, Z., Celotto, A.M., Romero, G., Wipf, P., & Palladino, M.J. (2012). Genetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesis. Neurobiol Dis, 45(1), 362-368.Elsevier. doi: 10.1016/j.nbd.2011.08.022.
Pizzo, C., Faral-Tello, P., Salinas, G., Flo, M., Robello, C., Wipf, P., & Graciela Mahler, S. (2012). Selenosemicarbazones as potent cruzipain inhibitors and their antiparasitic properties against Trypanosoma cruzi. MEDCHEMCOMM, 3(3), 362-368.Royal Society of Chemistry (RSC). doi: 10.1039/c2md00283c.
Seguin, S.P., Ireland, A.W., Gupta, T., Wright, C.M., Miyata, Y., Wipf, P., Pipas, J.M., Gestwicki, J.E., & Brodsky, J.L. (2012). A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication. Antiviral Res, 96(1), 70-81.Elsevier. doi: 10.1016/j.antiviral.2012.07.012.
Skoda, E.M., Davis, G.C., & Wipf, P. (2012). Allylic Amines as Key Building Blocks in the Synthesis of (E)-Alkene Peptide Isosteres. Org Process Res Dev, 16(1), 26-34.American Chemical Society (ACS). doi: 10.1021/op2002613.
Tandon, M., Wang, L., Xu, Q., Xie, X., Wipf, P., & Wang, Q.J. (2012). A targeted library screen reveals a new inhibitor scaffold for protein kinase D. In Jung, M. (Ed.). PLoS One, 7(9), e44653.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0044653.
Wang, L., Ma, C., Wipf, P., & Xie, X.Q. (2012). Linear and Nonlinear Support Vector Machine for the Classification of Human 5-HT1A Ligand Functionality. Mol Inform, 31(1), 85-95.Wiley. doi: 10.1002/minf.201100126.
Bernard, M.E., Kim, H., Berhane, H., Epperly, M.W., Franicola, D., Zhang, X., Houghton, F., Shields, D., Wang, H., Bakkenist, C.J., Frantz, M.C., Forbeck, E.M., Goff, J.P., Wipf, P., & Greenberger, J.S. (2011). GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines. Radiat Res, 176(5), 603-612.Radiation Research Society. doi: 10.1667/rr2624.1.
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Braunstein, M.J., Scott, S.S., Scott, C.M., Behrman, S., Walter, P., Wipf, P., Coplan, J.D., Chrico, W., Joseph, D., Brodsky, J.L., & Batuman, O. (2011). Antimyeloma Effects of the Heat Shock Protein 70 Molecular Chaperone Inhibitor MAL3-101. J Oncol, 2011(1), 232037.Hindawi. doi: 10.1155/2011/232037.
Bravo-Altamirano, K., George, K.M., Frantz, M.C., Lavalle, C.R., Tandon, M., Leimgruber, S., Sharlow, E.R., Lazo, J.S., Wang, Q.J., & Wipf, P. (2011). Synthesis and Structure-Activity Relationships of Benzothienothiazepinone Inhibitors of Protein Kinase D. ACS Med Chem Lett, 2(2), 154-159.American Chemical Society (ACS). doi: 10.1021/ml100230n.
Frantz, M.C., Pierce, J.G., Pierce, J.M., Kangying, L., Qingwei, W., Johnson, M., & Wipf, P. (2011). Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs. Org Lett, 13(9), 2318-2321.American Chemical Society (ACS). doi: 10.1021/ol200567p.
Gehret, J.J., Gu, L., Gerwick, W.H., Wipf, P., Sherman, D.H., & Smith, J.L. (2011). Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. J Biol Chem, 286(16), 14445-14454.Elsevier. doi: 10.1074/jbc.M110.214635.
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Goff, J.P., Epperly, M.W., Dixon, T., Wang, H., Franicola, D., Shields, D., Wipf, P., Li, S., Gao, X., & Greenberger, J.S. (2011). Radiobiologic effects of GS-nitroxide (JP4-039) on the hematopoietic syndrome. In Vivo, 25(3), 315-323.International Institute of Anticancer Research.
Hopkins, C.D., Schmitz, J.C., Chu, E., & Wipf, P. (2011). Total synthesis of (-)-CP2-disorazole C1. Org Lett, 13(15), 4088-4091.American Chemical Society (ACS). doi: 10.1021/ol2015994.
Hoye, A.T., & Wipf, P. (2011). Total synthesis of (-)-sessilifoliamide C and (-)-8-epi-stemoamide. Org Lett, 13(10), 2634-2637.American Chemical Society (ACS). doi: 10.1021/ol200743u.
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Kim, H., Bernard, M.E., Epperly, M.W., Shen, H., Amoscato, A., Dixon, T.M., Doemling, A.S., Li, S., Gao, X., Wipf, P., Wang, H., Zhang, X., Kagan, V.E., & Greenberger, J.S. (2011). Amelioration of radiation esophagitis by orally administered p53/Mdm2/Mdm4 inhibitor (BEB55) or GS-nitroxide. In Vivo, 25(6), 841-848.International Institute of AntiCancer Research.
Milner, E., Gardner, S., Moon, J., Grauer, K., Auschwitz, J., Bathurst, I., Caridha, D., Gerena, L., Gettayacamin, M., Johnson, J., Kozar, M., Lee, P., Leed, S., Li, Q., McCalmont, W., Melendez, V., Roncal, N., Sciotti, R., Smith, B., Sousa, J., Tungtaeng, A., Wipf, P., & Dow, G. (2011). Structure-activity relationships of 4-position diamine quinoline methanols as intermittent preventative treatment (IPT) against Plasmodium falciparum. J Med Chem, 54(18), 6277-6285.American Chemical Society (ACS). doi: 10.1021/jm200647u.
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Saiz, C., Wipf, P., & Mahler, G. (2011). Synthesis and ring-chain-ring tautomerism of bisoxazolidines, thiazolidinyloxazolidines, and spirothiazolidines. J Org Chem, 76(14), 5738-5746.American Chemical Society (ACS). doi: 10.1021/jo2008498.
Sharlow, E.R., Mustata Wilson, G., Close, D., Leimgruber, S., Tandon, M., Reed, R.B., Shun, T.Y., Wang, Q.J., Wipf, P., & Lazo, J.S. (2011). Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. In Bogyo, M. (Ed.). PLoS One, 6(10), e25134.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0025134.
Wang, L., Xie, Z., Wipf, P., & Xie, X.Q. (2011). Residue preference mapping of ligand fragments in the Protein Data Bank. J Chem Inf Model, 51(4), 807-815.American Chemical Society (ACS). doi: 10.1021/ci100386y.
Wipf, P., & Manojlovic, M.D. (2011). Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles. Beilstein J Org Chem, 7(1), 824-830.Beilstein Institut. doi: 10.3762/bjoc.7.94.
Zaware, N., Laporte, M.G., Farid, R., Liu, L., Wipf, P., & Floreancig, P.E. (2011). Diversity-oriented synthesis of a library of substituted tetrahydropyrones using oxidative carbon-hydrogen bond activation and click chemistry. Molecules, 16(5), 3648-3662.MDPI. doi: 10.3390/molecules16053648.
Epperly, M.W., Franicola, D., Shields, D., Rwigema, J.C., Stone, B., Zhang, X., McBride, W., Georges, G., Wipf, P., & Greenberger, J.S. (2010). Screening of antimicrobial agents for in vitro radiation protection and mitigation capacity, including those used in supportive care regimens for bone marrow transplant recipients. In Vivo, 24(1), 9-19.The International Institute of Anticancer Research.
Epperly, M.W., Goff, J.P., Li, S., Gao, X., Wipf, P., Dixon, T., Wang, H., Franicola, D., Shen, H., Rwigema, J.C.M., Kagan, V., Bernard, M., & Greenberger, J.S. (2010). Intraesophageal administration of GS-nitroxide (JP4-039) protects against ionizing irradiation-induced esophagitis. In Vivo, 24(6), 811-819.International Institute of Anticancer Research.
Gokhale, A., Rwigema, J.C., Epperly, M.W., Glowacki, J., Wang, H., Wipf, P., Goff, J.P., Dixon, T., Patrene, K., & Greenberger, J.S. (2010). Small molecule GS-nitroxide ameliorates ionizing irradiation-induced delay in bone wound healing in a novel murine model. In Vivo, 24(4), 377-385.International Institute of AntiCancer Research.
Hammill, J.T., Contreras-García, J., Virshup, A.M., Beratan, D., Yang, W., & Wipf, P. (2010). Synthesis and chemical diversity analysis of bicyclo[3.3.1]non-3-en-2-ones. Tetrahedron, 66(31), 5852-5862.Elsevier. doi: 10.1016/j.tet.2010.04.112.
Lavalle, C.R., Bravo-Altamirano, K., Giridhar, K.V., Chen, J., Sharlow, E., Lazo, J.S., Wipf, P., & Wang, Q.J. (2010). Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility. BMC Chem Biol, 10(1), 5.Springer Nature. doi: 10.1186/1472-6769-10-5.
LaValle, C.R., George, K.M., Sharlow, E.R., Lazo, J.S., Wipf, P., & Wang, Q.J. (2010). Protein kinase D as a potential new target for cancer therapy. Biochim Biophys Acta, 1806(2), 183-192.Elsevier. doi: 10.1016/j.bbcan.2010.05.003.
Lazo, J.S., Reese, C.E., Vogt, A., Vollmer, L.L., Kitchens, C.A., Günther, E., Graham, T.H., Hopkins, C.D., & Wipf, P. (2010). Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1. J Pharmacol Exp Ther, 332(3), 906-911.Elsevier. doi: 10.1124/jpet.109.162842.
Milner, E., McCalmont, W., Bhonsle, J., Caridha, D., Cobar, J., Gardner, S., Gerena, L., Goodine, D., Lanteri, C., Melendez, V., Roncal, N., Sousa, J., Wipf, P., & Dow, G.S. (2010). Anti-malarial activity of a non-piperidine library of next-generation quinoline methanols. Malar J, 9(1), 51.Springer Nature. doi: 10.1186/1475-2875-9-51.
Mishra, J.K., Wipf, P., & Sinha, S.C. (2010). Studies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofurans. J Comb Chem, 12(5), 609-612.American Chemical Society (ACS). doi: 10.1021/cc1000709.
Mo, T., Mi, X., Milner, E.E., Dow, G.S., & Wipf, P. (2010). Synthesis of an 8-pentafluorosulfanyl analog of the antimalarial agent mefloquine. TETRAHEDRON LETTERS, 51(39), 5137-5140.Elsevier. doi: 10.1016/j.tetlet.2010.07.113.
Tyurina, Y.Y., Tyurin, V.A., Kaynar, A.M., Kapralova, V.I., Wasserloos, K., Li, J., Mosher, M., Wright, L., Wipf, P., Watkins, S., Pitt, B.R., & Kagan, V.E. (2010). Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation. Am J Physiol Lung Cell Mol Physiol, 299(1), L73-L85.American Physiological Society. doi: 10.1152/ajplung.00035.2010.
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Wipf, P., & George, K.M. (2010). Regioselective Palladium-Catalyzed Cross-Coupling Reactions of 2,4,7-Trichloroquinazoline. Synlett, 2010(4), 644-648.Thieme. doi: 10.1055/s-0029-1219391.
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Fu, X.L., Moss, R.A., Sauers, R.R., & Wipf, P. (2005). The fragmentation of exo-5-norbornenyl-2-oxychlorocarbene:: stereochemistry and mechanism. TETRAHEDRON LETTERS, 46(24), 4265-4268.Elsevier. doi: 10.1016/j.tetlet.2005.03.208.
Ihle, N.T., Paine-Murrieta, G., Berggren, M.I., Baker, A., Tate, W.R., Wipf, P., Abraham, R.T., Kirkpatrick, D.L., & Powis, G. (2005). The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non-small cell lung cancer xenografts. Mol Cancer Ther, 4(9), 1349-1357.American Association for Cancer Research (AACR). doi: 10.1158/1535-7163.MCT-05-0149.
Janjic, J.M., Mu, Y., Kendall, C., Stephenson, C.R.J., Balachandran, R., Raccor, B.S., Lu, Y., Zhu, G., Xie, W., Wipf, P., & Day, B.W. (2005). New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides. Bioorg Med Chem, 13(1), 157-164.Elsevier. doi: 10.1016/j.bmc.2004.09.048.
Moss, R.A., Fu, X., Sauers, R.R., & Wipf, P. (2005). Endo entry to the nortricyclyl-norbornenyl cation system: stereochemistry in the fragmentation of endo-5-norbornenyl-2-oxychlorocarbene. J Org Chem, 70(21), 8454-8460.American Chemical Society (ACS). doi: 10.1021/jo051222o.
Moss, R.A., Fu, X., Tian, J., Sauers, R., & Wipf, P. (2005). Stereochemistry of oxachlorocarbene S(N)i reactions. Org Lett, 7(7), 1371-1374.American Chemical Society (ACS). doi: 10.1021/ol050185k.
Mu, Y., Stephenson, C.R.J., Kendall, C., Saini, S.P.S., Toma, D., Ren, S., Cai, H., Strom, S.C., Day, B.W., Wipf, P., & Xie, W. (2005). A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development. Mol Pharmacol, 68(2), 403-413.Elsevier. doi: 10.1124/mol.105.013292.
Nguyen, T.L., McGrath, C., Hermone, A.R., Burnett, J.C., Zaharevitz, D.W., Day, B.W., Wipf, P., Hamel, E., & Gussio, R. (2005). A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach. J Med Chem, 48(19), 6107-6116.American Chemical Society (ACS). doi: 10.1021/jm050502t.
Wipf, P., & Graham, T.H. (2005). Synthesis and hetero-Michael addition reactions of 2-alkynyl oxazoles and oxazolines. Org Biomol Chem, 3(1), 31-35.Royal Society of Chemistry (RSC). doi: 10.1039/b413604g.
Wipf, P., & Halter, R.J. (2005). Chemistry and biology of wortmannin. Org Biomol Chem, 3(11), 2053-2061.Royal Society of Chemistry (RSC). doi: 10.1039/b504418a.
Wipf, P., & Hopkins, T.D. (2005). Total synthesis and structure validation of (+)-bistramide C. Chem Commun (Camb), 0(27), 3421-3423.Royal Society of Chemistry (RSC). doi: 10.1039/b505100b.
Wipf, P., & Pierce, J.G. (2005). Synthesis of homoallylic amines by hydrozirconation-imine addition of allenes. Org Lett, 7(16), 3537-3540.American Chemical Society (ACS). doi: 10.1021/ol051266j.
Wipf, P., & Spencer, S.R. (2005). Asymmetric total syntheses of tuberostemonine, didehydrotuberostemonine, and 13-epituberostemonine. J Am Chem Soc, 127(1), 225-235.American Chemical Society (ACS). doi: 10.1021/ja044280k.
Wipf, P., & Stephenson, C.R.J. (2005). Three-component synthesis of alpha,beta-cyclopropyl-gamma-amino acids. Org Lett, 7(6), 1137-1140.American Chemical Society (ACS). doi: 10.1021/ol0501525.
Wipf, P., & Xiao, J. (2005). Convergent approach to (E)-alkene and cyclopropane peptide isosteres. Org Lett, 7(1), 103-106.American Chemical Society (ACS). doi: 10.1021/ol0477529.
Wipf, P., Coleman, C.M., Janjic, J.M., Iyer, P.S., Fodor, M.D., Shafer, Y.A., Stephenson, C.R.J., Kendall, C., & Day, B.W. (2005). Microwave-assisted "libraries from libraries" approach toward the synthesis of allyl- and C-cyclopropylalkylamides. J Comb Chem, 7(2), 322-330.American Chemical Society (ACS). doi: 10.1021/cc049842a.
Wipf, P., Fletcher, J.M., & Scarone, L. (2005). Microwave promoted oxazole synthesis: cyclocondensation cascade of oximes and acyl chlorides. TETRAHEDRON LETTERS, 46(33), 5463-5466.Elsevier. doi: 10.1016/j.tetlet.2005.06.063.
Wipf, P., Lynch, S.M., Powis, G., Birmingham, A., & Englund, E.E. (2005). Synthesis and biological activity of prodrug inhibitors of the thioredoxin-thioredoxin reductase system. Org Biomol Chem, 3(21), 3880-3882.Royal Society of Chemistry (RSC). doi: 10.1039/b510718k.
Wipf, P., Mahler, S.G., & Okumura, K. (2005). Metathesis reactions of pyrazolotriazinones generate dynamic combinatorial libraries. Org Lett, 7(20), 4483-4486.American Chemical Society (ACS). doi: 10.1021/ol051839s.
Wipf, P., Pierce, J.G., & Zhuang, N. (2005). Silver(I)-catalyzed addition of zirconocenes to glycal epoxides. A new synthesis of alpha-C-glycosides. Org Lett, 7(3), 483-485.American Chemical Society (ACS). doi: 10.1021/ol0475414.
Wipf, P., Waller, D.L., & Reeves, J.T. (2005). Transition-metal-mediated cascade reactions: the water-accelerated carboalumination-Claisen rearrangement-carbonyl addition reaction. J Org Chem, 70(20), 8096-8102.American Chemical Society (ACS). doi: 10.1021/jo051211v.
Wipf, P., Werner, S., Woo, G.H.C., Stephenson, C.R.J., Walczak, M.A.A., Coleman, C.M., & Twining, L.A. (2005). Application of divergent multi-component reactions in the synthesis of a library of peptidomimetics based on γ-amino-α,β-cyclopropyl acids. TETRAHEDRON, 61(48), 11488-11500.Elsevier. doi: 10.1016/j.tet.2005.09.016.
Wipf, P., Xiao, J., Jiang, J., Belikova, N.A., Tyurin, V.A., Fink, M.P., & Kagan, V.E. (2005). Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates. J Am Chem Soc, 127(36), 12460-12461.American Chemical Society (ACS). doi: 10.1021/ja053679l.
Wipf, P., Xiao, J.B., & Geib, S.J. (2005). Imine additions of internal alkynes for the synthesis of trisubstituted (E)-alkene and cyclopropane peptide isosteres. ADVANCED SYNTHESIS & CATALYSIS, 347(11-13), 1605-1613.Wiley. doi: 10.1002/adsc.200505171.
Zuber, G., Goldsmith, M.R., Beratan, D.N., & Wipf, P. (2005). Assignment of the absolute configuration of [n]-ladderanes by TD-DFT optical rotation calculations. Chirality, 17(8), 507-510.Wiley. doi: 10.1002/chir.20190.
Zuber, G., Goldsmith, M.R., Hopkins, T.D., Beratan, D.N., & Wipf, P. (2005). Systematic assignment of the configuration of flexible natural products by spectroscopic and computational methods: the bistramide C analysis. Org Lett, 7(23), 5269-5272.American Chemical Society (ACS). doi: 10.1021/ol052154v.
Brisson, M., Nguyen, T., Vogt, A., Yalowich, J., Giorgianni, A., Tobi, D., Bahar, I., Stephenson, C.R.J., Wipf, P., & Lazo, J.S. (2004). Discovery and characterization of novel small molecule inhibitors of human Cdc25B dual specificity phosphatase. Mol Pharmacol, 66(4), 824-833.Elsevier. doi: 10.1124/mol.104.001784.
Fewell, S.W., Smith, C.M., Lyon, M.A., Dumitrescu, T.P., Wipf, P., Day, B.W., & Brodsky, J.L. (2004). Small molecule modulators of endogenous and co-chaperone-stimulated Hsp70 ATPase activity. J Biol Chem, 279(49), 51131-51140.Elsevier. doi: 10.1074/jbc.M404857200.
Han, Y., Shen, H., Carr, B.I., Wipf, P., Lazo, J.S., & Pan, S.S. (2004). NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors. J Pharmacol Exp Ther, 309(1), 64-70.Elsevier. doi: 10.1124/jpet.103.059477.
Ihle, N.T., Williams, R., Chow, S., Chew, W., Berggren, M.I., Paine-Murrieta, G., Minion, D.J., Halter, R.J., Wipf, P., Abraham, R., Kirkpatrick, L., & Powis, G. (2004). Molecular pharmacology and antitumor activity of PX-866, a novel inhibitor of phosphoinositide-3-kinase signaling. Mol Cancer Ther, 3(7), 763-772.American Association for Cancer Research (AACR). doi: 10.1158/1535-7163.763.3.7.
Oguri, T., Nemoto, K., Bansal, P., Wipf, P., & Lazo, J.S. (2004). Induction of Cdc25B expression by epidermal growth factor and transforming growth factor-alpha. Biochem Pharmacol, 68(11), 2221-2227.Elsevier. doi: 10.1016/j.bcp.2004.08.011.
Wipf, P., & Graham, T.H. (2004). Total synthesis of (-)-disorazole C1. J Am Chem Soc, 126(47), 15346-15347.American Chemical Society (ACS). doi: 10.1021/ja0443068.
Wipf, P., & Nunes, R.L. (2004). Selective carbon-carbon bond formations with alkenylzirconocenes. TETRAHEDRON, 60(6), 1269-1279.Elsevier. doi: 10.1016/j.tet.2003.12.018.
Wipf, P., Aoyama, Y., & Benedum, T.E. (2004). A practical method for oxazole synthesis by cycloisomerization of propargyl amides. Org Lett, 6(20), 3593-3595.American Chemical Society (ACS). doi: 10.1021/ol0485058.
Wipf, P., Janjic, J., & Stephenson, C.R.J. (2004). Microwave-assisted synthesis of allylic amines: considerable rate acceleration in the hydrozirconation-transmetalation-aldimine addition sequence. Org Biomol Chem, 2(4), 443-445.Royal Society of Chemistry (RSC). doi: 10.1039/b316741k.
Wipf, P., Joo, B., Nguyen, T., & Lazo, J.S. (2004). Synthesis and biological evaluation of caulibugulones A-E. Org Biomol Chem, 2(15), 2173-2174.Royal Society of Chemistry (RSC). doi: 10.1039/b408184f.
Wipf, P., Lynch, S.M., Birmingham, A., Tamayo, G., Jiménez, A., Campos, N., & Powis, G. (2004). Natural product based inhibitors of the thioredoxin-thioredoxin reductase system. Org Biomol Chem, 2(11), 1651-1658.Royal Society of Chemistry (RSC). doi: 10.1039/b402431a.
Wipf, P., Minion, D.J., Halter, R.J., Berggren, M.I., Ho, C.B., Chiang, G.G., Kirkpatrick, L., Abraham, R., & Powis, G. (2004). Synthesis and biological evaluation of synthetic viridins derived from C(20)-heteroalkylation of the steroidal PI-3-kinase inhibitor wortmannin. Org Biomol Chem, 2(13), 1911-1920.Royal Society of Chemistry (RSC). doi: 10.1039/b405431h.
Wipf, P., Reeves, J.T., & Day, B.W. (2004). Chemistry and biology of curacin A. Curr Pharm Des, 10(12), 1417-1437.Bentham Science Publishers. doi: 10.2174/1381612043384853.
Wipf, P., Stephenson, C.R.J., & Walczak, M.A.A. (2004). Diversity-oriented synthesis of azaspirocycles. Org Lett, 6(17), 3009-3012.American Chemical Society (ACS). doi: 10.1021/ol0487783.
Wipf, P., Takada, T., & Rishel, M.J. (2004). Synthesis of the tubuvaline-tubuphenylalanine (Tuv-Tup) fragment of tubulysin. Org Lett, 6(22), 4057-4060.American Chemical Society (ACS). doi: 10.1021/ol048252i.
Lazo, J.S., & Wipf, P. (2003). Small molecule regulation of phosphatase-dependent cell signaling pathways. Oncol Res, 13(6-10), 347-352.Tech Science Press. doi: 10.3727/096504003108748555.
Vogt, A., Cooley, K.A., Brisson, M., Tarpley, M.G., Wipf, P., & Lazo, J.S. (2003). Cell-active dual specificity phosphatase inhibitors identified by high-content screening. Chem Biol, 10(8), 733-742.Elsevier. doi: 10.1016/s1074-5521(03)00170-4.
Wipf, P., & Graham, T.H. (2003). Photoactivated tungsten hexacarbonyl-catalyzed conversion of alkynols to glycals. J Org Chem, 68(23), 8798-8807.American Chemical Society (ACS). doi: 10.1021/jo034813s.
Wipf, P., & Lynch, S.M. (2003). Synthesis of highly oxygenated dinaphthyl ethers via SNAr reactions promoted by Barton's base. Org Lett, 5(7), 1155-1158.American Chemical Society (ACS). doi: 10.1021/ol034286z.
Wipf, P., & Stephenson, C.R.J. (2003). Dimethylzinc-mediated addition of alkenylzirconocenes to alpha-keto and alpha-imino esters. Org Lett, 5(14), 2449-2452.American Chemical Society (ACS). doi: 10.1021/ol0347141.
Wipf, P., Jayasuriya, N., & Ribe, S. (2003). On the role of chiral catalysts in the alkenyl zirconocene/zinc addition to aldehydes: a study of ligand loading and asymmetric amplification. Chirality, 15(3), 208-212.Wiley. doi: 10.1002/chir.10176.
Wipf, P., Kendall, C., & Stephenson, C.R.J. (2003). Dimethylzinc-mediated additions of alkenylzirconocenes to aldimines. New methodologies for allylic amine and C-cyclopropylalkylamine syntheses. J Am Chem Soc, 125(3), 761-768.American Chemical Society (ACS). doi: 10.1021/ja028092a.
Wipf, P., Pierce, J.G., & Wang, X.D. (2003). Investigation of ligand loading and asymmetric amplification in CHAOx-catalyzed asymmetric diethylzinc additions. TETRAHEDRON-ASYMMETRY, 14(22), 3605-3611.Elsevier. doi: 10.1016/j.tetasy.2003.07.022.
Wipf, P., Stephenson, C.R.J., & Okumura, K. (2003). Transition-metal-mediated cascade reactions: C,C-dicyclopropylmethylamines by way of double C,C-sigma-bond insertion into bicyclobutanes. J Am Chem Soc, 125(48), 14694-14695.American Chemical Society (ACS). doi: 10.1021/ja038623a.
El Sayed, K.A., Yousaf, M., Hamann, M.T., Avery, M.A., Kelly, M., & Wipf, P. (2002). Microbial and chemical transformation studies of the bioactive marine sesquiterpenes (S)-(+)-curcuphenol and -curcudiol isolated from a deep reef collection of the Jamaican sponge Didiscus oxeata. J Nat Prod, 65(11), 1547-1553.American Chemical Society (ACS). doi: 10.1021/np020213x.
Lazo, J.S., Nemoto, K., Pestell, K.E., Cooley, K., Southwick, E.C., Mitchell, D.A., Furey, W., Gussio, R., Zaharevitz, D.W., Joo, B., & Wipf, P. (2002). Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Mol Pharmacol, 61(4), 720-728.Elsevier. doi: 10.1124/mol.61.4.720.
Lyon, M.A., Ducruet, A.P., Wipf, P., & Lazo, J.S. (2002). Dual-specificity phosphatases as targets for antineoplastic agents. Nat Rev Drug Discov, 1(12), 961-976.Springer Nature. doi: 10.1038/nrd963.
Vogt, A., Pestell, K.E., Day, B.W., Lazo, J.S., & Wipf, P. (2002). The antisignaling agent SC-alpha alpha delta 9, 4-(benzyl-(2-[(2,5-diphenyloxazole-4-carbonyl)amino]ethyl)carbamoyl)- 2-decanoylaminobutyric acid, is a structurally unique phospholipid analogue with phospholipase C inhibitory activity. Mol Cancer Ther, 1(11), 885-892.American Association for Cancer Research.
Wipf, P., & Kendall, C. (2002). Novel applications of alkenyl zirconocenes. Chemistry, 8(8), 1778-1784.Wiley. doi: 10.1002/1521-3765(20020415)8:8<1778::aid-chem1778>3.0.co;2-h.
Wipf, P., & Reeves, J.T. (2002). A formal total synthesis of leucascandrolide A. Chem Commun (Camb), 0(18), 2066-2067.Royal Society of Chemistry (RSC). doi: 10.1039/b207383h.
Wipf, P., & Soth, M.J. (2002). Synthesis of the C(1)-C(18) segment of lophotoxin and pukalide. Control of 2-alkenylfuran (E/Z)-configuration. Org Lett, 4(10), 1787-1790.American Chemical Society (ACS). doi: 10.1021/ol025861m.
Wipf, P., & Wang, X. (2002). Parallel synthesis of oxazolines and thiazolines by tandem condensation-cyclodehydration of carboxylic acids with amino alcohols and aminothiols. J Comb Chem, 4(6), 656-660.American Chemical Society (ACS). doi: 10.1021/cc020041m.
Wipf, P., & Wang, X. (2002). A new ligand scaffold for catalytic asymmetric alkylzinc additions to aldehydes. Org Lett, 4(7), 1197-1200.American Chemical Society (ACS). doi: 10.1021/ol025600c.
Wipf, P., Hopkins, C.R., Phillips, E.O., & Lazo, J.S. (2002). Separation of Cdc25 dual specificity phosphatase inhibition and DNA cleaving activities in a focused library of analogs of the antitumor antibiotic Dnacin. TETRAHEDRON, 58(32), 6367-6372.Elsevier. doi: 10.1016/S0040-4020(02)00636-1.
Wipf, P., Nunes, R.L., & Ribe, S. (2002). Water-accelerated organometallic chemistry: Alkyne carboalumination - Sulfinimine addition and asymmetric synthesis of allylic amines. HELVETICA CHIMICA ACTA, 85(10), 3478-3488.Wiley. doi: 10.1002/1522-2675(200210)85:10<3478::AID-HLCA3478>3.0.CO;2-E.
Wipf, P., Rector, S.R., & Takahashi, H. (2002). Total synthesis of (-)-tuberostemonine. J Am Chem Soc, 124(50), 14848-14849.American Chemical Society (ACS). doi: 10.1021/ja028603t.
Wipf, P., Reeves, J.T., Balachandran, R., & Day, B.W. (2002). Synthesis and biological evaluation of structurally highly modified analogues of the antimitotic natural product curacin A. J Med Chem, 45(9), 1901-1917.American Chemical Society (ACS). doi: 10.1021/jm0105171.
Wipf, P., Uto, Y., & Yoshimura, S. (2002). Total synthesis of a stereoisomer of bistramide C and assignment of configuration of the natural product. Chemistry, 8(7), 1670-1681.Wiley. doi: 10.1002/1521-3765(20020402)8:7<1670::aid-chem1670>3.0.co;2-4.
Lazo, J.S., Aslan, D.C., Southwick, E.C., Cooley, K.A., Ducruet, A.P., Joo, B., Vogt, A., & Wipf, P. (2001). Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. J Med Chem, 44(24), 4042-4049.American Chemical Society (ACS). doi: 10.1021/jm0102046.
Lazo, J.S., Tamura, K., Vogt, A., Jung, J.K., Rodriguez, S., Balachandran, R., Day, B.W., & Wipf, P. (2001). Antimitotic actions of a novel analog of the fungal metabolite palmarumycin CP1. J Pharmacol Exp Ther, 296(2), 364-371.Elsevier. doi: 10.1016/s0022-3565(24)38788-9.
Ribe, S., & Wipf, P. (2001). Water-accelerated organic transformations. CHEMICAL COMMUNICATIONS, 0(4), 299-307.Royal Society of Chemistry (RSC). doi: 10.1039/b008252j.
Specht, K.M., Nam, J., Ho, D.M., Berova, N., Kondru, R.K., Beratan, D.N., Wipf, P., Pascal, R.A., & Kahne, D. (2001). Determining absolute configuration in flexible molecules: a case study. J Am Chem Soc, 123(37), 8961-8966.American Chemical Society (ACS). doi: 10.1021/ja0104406.
Wipf, P., & Aslan, D.C. (2001). Synthesis of bicyclic ortho esters by epoxy ester rearrangements and study of their ring-opening reactions. J Org Chem, 66(1), 337-343.American Chemical Society (ACS). doi: 10.1021/jo005665y.
Wipf, P., & Graham, T.H. (2001). Synthesis of the C(1')--C(11') segment of leucascandrolide A. J Org Chem, 66(9), 3242-3245.American Chemical Society (ACS). doi: 10.1021/jo005787q.
Wipf, P., & Hopkins, C.R. (2001). Enantioselective synthesis of the AB-ring system of the antitumor antibiotic tetrazomine. J Org Chem, 66(9), 3133-3139.American Chemical Society (ACS). doi: 10.1021/jo015512q.
Wipf, P., & Kendall, C. (2001). Tandem zirconocene homologation-aldimine allylation. Org Lett, 3(17), 2773-2776.American Chemical Society (ACS). doi: 10.1021/ol0163880.
Wipf, P., & Methot, J.L. (2001). Synthetic studies toward diazonamide A. A novel approach for polyoxazole synthesis. Org Lett, 3(9), 1261-1264.American Chemical Society (ACS). doi: 10.1021/ol0157196.
Wipf, P., & Reeves, J.T. (2001). Glycosylation via Cp2ZrCl2/AgClO4-mediated activation of anomeric sulfoxides. J Org Chem, 66(23), 7910-7914.American Chemical Society (ACS). doi: 10.1021/jo015952h.
Wipf, P., & Ribe, S. (2001). Water-accelerated tandem Claisen rearrangement-catalytic asymmetric carboalumination. Org Lett, 3(10), 1503-1505.American Chemical Society (ACS). doi: 10.1021/ol015816z.
Wipf, P., Aslan, D.C., Southwick, E.C., & Lazo, J.S. (2001). Sulfonylated aminothiazoles as new small molecule inhibitors of protein phosphatases. Bioorg Med Chem Lett, 11(3), 313-317.Elsevier. doi: 10.1016/s0960-894x(00)00658-2.
Wipf, P., Hopkins, T.D., Jung, J.K., Rodriguez, S., Birmingham, A., Southwick, E.C., Lazo, J.S., & Powis, G. (2001). New inhibitors of the thioredoxin-thioredoxin reductase system based on a naphthoquinone spiroketal natural product lead. Bioorg Med Chem Lett, 11(19), 2637-2641.Elsevier. doi: 10.1016/s0960-894x(01)00525-x.
Ducruet, A.P., Rice, R.L., Tamura, K., Yokokawa, F., Yokokawa, S., Wipf, P., & Lazo, J.S. (2000). Identification of new Cdc25 dual specificity phosphatase inhibitors in a targeted small molecule array. Bioorg Med Chem, 8(6), 1451-1466.Elsevier. doi: 10.1016/s0968-0896(00)00069-9.
Kondru, R.K., Beratan, D.N., Friestad, G.K., Smith, A.B., & Wipf, P. (2000). Chiral action at a distance: remote substituent effects on the optical activity of calyculins A and B. Org Lett, 2(11), 1509-1512.American Chemical Society (ACS). doi: 10.1021/ol005634p.
Lazo, J.S., & Wipf, P. (2000). Combinatorial chemistry and contemporary pharmacology. J Pharmacol Exp Ther, 293(3), 705-709.Wiley. doi: 10.1002/chin.200043259.
Pestell, K.E., Ducruet, A.P., Wipf, P., & Lazo, J.S. (2000). Small molecule inhibitors of dual specificity protein phosphatases. Oncogene, 19(56), 6607-6612.Springer Nature. doi: 10.1038/sj.onc.1204084.
Phillips, A.J., Uto, Y., Wipf, P., Reno, M.J., & Williams, D.R. (2000). Synthesis of functionalized oxazolines and oxazoles with DAST and Deoxo-Fluor. Org Lett, 2(8), 1165-1168.American Chemical Society (ACS). doi: 10.1021/ol005777b.
Ribe, S., Kondru, R.K., Beratan, D.N., & Wipf, P. (2000). Optical rotation computation, total synthesis, and stereochemistry assignment of the marine natural product pitiamide A. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 122(19), 4608-4617.American Chemical Society (ACS). doi: 10.1021/ja9945313.
Vogt, A., Wang, A.S., Johnson, C.S., Fabisiak, J.P., Wipf, P., & Lazo, J.S. (2000). In vivo antitumor activity and induction of insulin-like growth factor-1-resistant apoptosis by SC-alphaalphadelta9. J Pharmacol Exp Ther, 292(2), 530-537.Elsevier. doi: 10.1016/s0022-3565(24)35322-4.
Wipf, P., & Jung, J.K. (2000). Formal total synthesis of (+)-diepoxin sigma. J Org Chem, 65(20), 6319-6337.American Chemical Society (ACS). doi: 10.1021/jo000684t.
Wipf, P., & Methot, J.L. (2000). Total synthesis and stereochemical revision of (+)-aeruginosin 298-A. Org Lett, 2(26), 4213-4216.American Chemical Society (ACS). doi: 10.1021/ol006759x.
Wipf, P., & Ribe, S. (2000). Water/MAO acceleration of the zirconocene-catalyzed asymmetric methylalumination of alpha-olefins. Org Lett, 2(12), 1713-1716.American Chemical Society (ACS). doi: 10.1021/ol005865w.
Wipf, P., & Uto, Y. (2000). Total synthesis and revision of stereochemistry of the marine metabolite trunkamide A. J Org Chem, 65(4), 1037-1049.American Chemical Society (ACS). doi: 10.1021/jo9914566.
Wipf, P., Aslan, D.C., Luci, D.K., Southwick, E.C., & Lazo, J.S. (2000). Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors. Biotechnol Bioeng, 71(1), 58-70.Wiley. doi: 10.1002/(sici)1097-0290(200024)71:1<58::aid-bit9>3.0.co;2-0.
Kondru, R.K., Wipf, P., & Beratan, D.N. (1999). Structural and conformational dependence of optical rotation angles. JOURNAL OF PHYSICAL CHEMISTRY A, 103(33), 6603-6611.American Chemical Society (ACS). doi: 10.1021/jp990697e.
Wipf, P., & Coish, P.D.G. (1999). Total Synthesis of (±)-Nisamycin. J Org Chem, 64(14), 5053-5061.American Chemical Society (ACS). doi: 10.1021/jo990413m.
Wipf, P., & Hopkins, C.R. (1999). Efficient Synthesis of 1,4-Dihydro-2H-isoquinoline-3,5,8-triones via Cyclobutene Ring Expansion. J Org Chem, 64(18), 6881-6887.American Chemical Society (ACS). doi: 10.1021/jo990089v.
Wipf, P., & Jung, J.K. (1999). Nucleophilic additions to 4,4-disubstituted 2,5-cyclohexadienones: can dipole effects control facial selectivity?. Chem Rev, 99(5), 1469-1480.American Chemical Society (ACS). doi: 10.1021/cr9803838.
Wipf, P., & Methot, J.L. (1999). Silver(I)-catalyzed addition of zirconocenes to epoxy esters: A new entry to 1,4-dicarbonyl compounds and pyridazinones. ORGANIC LETTERS, 1(8), 1253-1255.American Chemical Society (ACS). doi: 10.1021/ol990924v.
Wipf, P., & Weiner, W.S. (1999). Enantioselective Synthesis and Photoracemization Studies of (+)-2-Cyclopropyl-7,8-dimethoxy-2H- chromene-5-carboxylic Acid Methyl Ester, an Advanced Intermediate of a Dihydrofolate Reductase Inhibitor. J Org Chem, 64(14), 5321-5324.American Chemical Society (ACS). doi: 10.1021/jo990352s.
Wipf, P., Tsuchimoto, T., & Takahashi, H. (1999). Synthetic applications of ortho esters. PURE AND APPLIED CHEMISTRY, 71(3), 415-421.De Gruyter. doi: 10.1351/pac199971030415.
Kondru, R.K., Lim, S., Wipf, P., & Beratan, D.N. (1997). Synthetic and model computational studies of molar rotation additivity for interacting chiral centers: a reinvestigation of van't Hoff's principle. Chirality, 9(5-6), 469-477.Wiley. doi: 10.1002/(SICI)1520-636X(1997)9:5/6<469::AID-CHIR13>3.0.CO;2-M.
Rice, R.L., Rusnak, J.M., Yokokawa, F., Yokokawa, S., Messner, D.J., Boynton, A.L., Wipf, P., & Lazo, J.S. (1997). A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side chain variation. Biochemistry, 36(50), 15965-15974.American Chemical Society (ACS). doi: 10.1021/bi971338h.
Studer, A., Jeger, P., Wipf, P., & Curran, D.P. (1997). Fluorous Synthesis: Fluorous Protocols for the Ugi and Biginelli Multicomponent Condensations. J Org Chem, 62(9), 2917-2924.American Chemical Society (ACS). doi: 10.1021/jo970095w.
Wipf, P., & Coish, P.D.G. (1997). Organozirconocene-mediated polyene synthesis: Preparation of asukamycin and manumycin A side chains. TETRAHEDRON LETTERS, 38(29), 5073-5076.Elsevier. doi: 10.1016/S0040-4039(97)01129-5.
Wipf, P., & Jung, J.K. (1997). Long-range electrostatic effects in synthesis: Dipole-controlled nucleophilic addition to a naphthoquinone acetal in model studies toward diepoxin sigma. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 36(7), 764-767.Wiley. doi: 10.1002/anie.199707641.
Goldstein, D.M., & Wipf, P. (1996). Studies toward the synthesis of Stemona alkaloids; A short synthesis of the tricyclic core of tuberostemonines. TETRAHEDRON LETTERS, 37(6), 739-742.Elsevier. doi: 10.1016/0040-4039(95)02302-X.
Wipf, P., & Fritch, P.C. (1996). Total synthesis and assignment of configuration of lissoclinamide 7. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118(49), 12358-12367.American Chemical Society (ACS). doi: 10.1021/ja962859f.
Wipf, P., & Jahn, H. (1996). Synthetic applications of organochlorozirconocene complexes. TETRAHEDRON, 52(40), 12853-12910.Elsevier. doi: 10.1016/0040-4020(96)00754-5.
Wipf, P., Li, W., Adeyeye, C.M., Rusnak, J.M., & Lazo, J.S. (1996). Synthesis of chemoreversible prodrugs of ara-C with variable time-release profiles. Biological evaluation of their apoptotic activity. Bioorg Med Chem, 4(10), 1585-1596.Elsevier. doi: 10.1016/0968-0896(96)00153-8.
WIPF, P., & XU, W.J. (1995). ZIRCONOCENE-CATALYZED CATIONIC DIELS-ALDER REACTIONS. TETRAHEDRON, 51(15), 4551-4562.Elsevier. doi: 10.1016/0040-4020(94)01140-U.
WIPF, P. (1993). TRANSMETALATION REACTIONS IN ORGANOCOPPER CHEMISTRY. SYNTHESIS-STUTTGART, 1993(6), 537-557.Thieme. doi: 10.1055/s-1993-25900.
WIPF, P., & XU, W.J. (1993). SYNTHESIS AND REACTIVITY OF DIOXYCARBENIUM IONS FROM EPOXY ESTERS AND CATIONIC ZIRCONIUM COMPLEXES. JOURNAL OF ORGANIC CHEMISTRY, 58(22), 5880-5882.American Chemical Society (ACS). doi: 10.1021/jo00074a006.