Pitt | Swanson Engineering

Welcome to the Cell Migration Lab (CML) of Dr. Partha Roy

Our main research interests are to: a) gain novel insights on how dysregulation of fundamental drivers of cell migration contributes to metastatic progression of solid cancers and pathological angiogenesis; and b) develop translational strategies exploiting the pathways of dysregulation as a means to suppress metastatic phenotype of cancer cells and angiogenesis-dependent pathology. 

We use a variety of experimental approaches including mammary gland-related techniques, RNAi, 2D gel electrophoresis, genetically engineered mouse models of cancer, tumor xenografts, in vitro and in vivo angiogenesis assays, functional genomics and proteomics, live cell imaging and small molecule screening.