headshot of Keith Vogt

Keith Vogt

Associate Professor
keith.vogt@pitt.edu
(412) 647-3147
Anesthesiology faculty page Bioengineering Department

overview

I am an anesthesiologist, biomedical engineer, and physician-scientist who predominantly uses human cognitive neuroscience methods to investigate phenomena relevant to the clinical practice of anesthesiology and perioperative medicine. My long-standing involvement in pain functional neuroimaging research began in 2004 with the optimization work I did as my doctoral research. Using experimental pain as a cognitive experimental task, I collected physiologic data during functional MRI scanning and used these to correct the images for signal fluctuations unrelated to the neural response of interest. During my NRSA postdoctoral fellowship, I began the anesthetic neuroscience work that is ongoing. My current research continues to use functional MRI and complementary neuroscience research techniques to examine the interacting effects in the human brain when the systems for memory encoding, pain processing, and threat response are modulated by the diverse anesthetics propofol, dexmedetomidine, and fentanyl. This has been successfully funded by NIGMS. Through this work, I developed a strong and diverse network of mentors and other collaborators who have helped me to develop further expertise in MRI acquisition and analysis, cognitive neuroscience of pain and memory, and anesthetic pharmacology. I am deeply committed to training future researchers, particularly those at interface of engineering, neuroscience, and medicine. I am committed to fostering an inclusive and supportive laboratory environment where diverse trainees can reach their maximal potential, through a comprehensive partnership in career development.

about

PhD, Ohio State University, 2009

MD, Ohio State University, 2011

Vogt, K.M., Ibinson, J.W., Burlew, A.C., Smith, C.T., Aizenstein, H.J., & Fiez, J.A. (2023). Brain connectivity under light sedation with midazolam and ketamine during task performance and the periodic experience of pain: Examining concordance between different approaches for seed-based connectivity analysis. BRAIN IMAGING AND BEHAVIOR, 17(5), 519-529.Springer Science and Business Media LLC. doi: 10.1007/s11682-023-00782-6.

Norton, C.M., Ibinson, J.W., Pcola, S.J., Popov, V., Tremel, J.J., Reder, L.M., Fiez, J.A., & Vogt, K.M. (2022). Neutral auditory words immediately followed by painful electric shock may show reduced next-day recollection. EXPERIMENTAL BRAIN RESEARCH, 240(11), 2939-2951.Springer Science and Business Media LLC. doi: 10.1007/s00221-022-06467-8.

Vogt, K.M., Citro, A.T., Adams, P.S., Metro, D.G., & Sakai, T. (2022). Early immersion in a dedicated one-month Anesthesiology Professional Practice rotation for Post-Graduate Year-1 interns is associated with an increase in scholarly activity during residency. JOURNAL OF CLINICAL ANESTHESIA, 76, 110566.Elsevier BV. doi: 10.1016/j.jclinane.2021.110566.

Vlisides, P.E., Vogt, K.M., Pal, D., Schnell, E., Armstead, W.M., Brambrink, A.M., Kuo, P., Nelson, P., Vacas, S., Goettel, N., Aglio, L.S., Farag, E., Gorji, R., Garcia, P.S., & Koerner, I.P. (2021). Roadmap for Conducting Neuroscience Research in the COVID-19 Era and Beyond: Recommendations From the SNACC Research Committee. JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY, 33(2), 100-106.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/ANA.0000000000000758.

Citro, A.T., Norton, C.M., Pcola, S.J., & Vogt, K.M. (2020). Psychometric and electrodermal activity data from an experimental paradigm of memory encoding with some items periodically followed by painful electric shock. Data in Brief, 31, 105669.Elsevier BV. doi: 10.1016/j.dib.2020.105669.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. (2020). Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. BMC ANESTHESIOLOGY, 20(1), 62.Springer Science and Business Media LLC. doi: 10.1186/s12871-020-00974-3.

Schnetz, M.P., Hochheiser, H.S., Danks, D.J., Landsittel, D.P., Vogt, K.M., Ibinson, J.W., Whitehurst, S.L., McDermott, S.P., Duque, M.G., & Kaynar, A.M. (2019). The triple variable index combines information generated over time from common monitoring variables to identify patients expressing distinct patterns of intraoperative physiology. BMC MEDICAL RESEARCH METHODOLOGY, 19(1), 17.Springer Science and Business Media LLC. doi: 10.1186/s12874-019-0660-9.

Vogt, K.M., Norton, C.M., Speer, L.E., Tremel, J.J., Ibinson, J.W., Reder, L.M., & Fiez, J.A. (2019). Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation. EXPERIMENTAL BRAIN RESEARCH, 237(7), 1615-1627.Springer Science and Business Media LLC. doi: 10.1007/s00221-019-05534-x.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. (2018). Functional MRI in Pain Management. In Functional MRI. (pp. 158-173).Oxford University Press. doi: 10.1093/med/9780190297763.003.0009.

Manelis, A., Popov, V., Paynter, C., Walsh, M., Wheeler, M.E., Vogt, K.M., & Reder, L.M. (2017). Cortical Networks Involved in Memory for Temporal Order. JOURNAL OF COGNITIVE NEUROSCIENCE, 29(7), 1253-1266.MIT Press - Journals. doi: 10.1162/jocn_a_01123.

Vogt, K.M., Becker, C.J., Wasan, A.D., & Ibinson, J.W. (2016). Human Posterior Insula Functional Connectivity Differs Between Electrical Pain and the Resting State. Brain Connect, 6(10), 786-794.Mary Ann Liebert Inc. doi: 10.1089/brain.2016.0436.

Ibinson, J.W., Vogt, K.M., Taylor, K.B., Dua, S.B., Becker, C.J., Loggia, M., & Wasan, A.D. (2015). Optimizing and Interpreting Insular Functional Connectivity Maps Obtained During Acute Experimental Pain: The Effects of Global Signal and Task Paradigm Regression. Brain Connect, 5(10), 649-657.Mary Ann Liebert Inc. doi: 10.1089/brain.2015.0354.

Ibinson, J.W., & Vogt, K.M. (2013). Pain Does Not Follow the Boxcar Model: Temporal Dynamics of the BOLD fMRI Signal During Constant Current Painful Electric Nerve Stimulation. JOURNAL OF PAIN, 14(12), 1611-1619.Elsevier BV. doi: 10.1016/j.jpain.2013.08.004.

Vogt, K.M., Ibinson, J.W., Schmalbrock, P., & Small, R.H. (2011). Comparison between end-tidal CO2 and respiration volume per time for detecting BOLD signal fluctuations during paced hyperventilation. MAGNETIC RESONANCE IMAGING, 29(9), 1186-1194.Elsevier BV. doi: 10.1016/j.mri.2011.07.011.

Vogt, K.M., Ibinson, J.W., Schmalbrock, P., & Small, R.H. (2011). The impact of physiologic noise correction applied to functional MRI of pain at 1.5 and 3.0 T. MAGNETIC RESONANCE IMAGING, 29(6), 819-826.Elsevier BV. doi: 10.1016/j.mri.2011.02.017.

Vogt, K.M., Kauh, C.Y., Holder, D.M., & Dephilip, R.M. (2011). Fluoroscopic Angiography in the Gross Anatomy Dissection Laboratory: Visualizing the Aortic Arch and Its Branches in a Cadaver. CLINICAL ANATOMY, 24(2), 253-257.Wiley. doi: 10.1002/ca.21080.

Vogt, K.M., Kauh, C.Y., Holder, D.M., & DePhilip, R.M. (2011). Reply: Aberrant Right Subclavian Artery and Fluoroscopy in the Dissection Laboratory. CLINICAL ANATOMY, 24(4), 509.Wiley. doi: 10.1002/ca.21132.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. Human posterior insula to posterior cingulate functional connectivity is related to the subjective intensity of acute pain. Cold Spring Harbor Laboratory. doi: 10.1101/246959.

Chelly, J.E., Holtzman, M.P., Bartlett, D.L., Choudry, H.A., Pingpank, J.F., Zureikat, A.H., Norton, B.E., Sadhasivam, S.K., & Vogt, K.M. Reduction in postoperative opioid requirement associated with use of the NSS-2® Bridge device, a disposable auriculo-nerve field stimulator, and factors affecting the response in cancer patients undergoing abdominal surgical procedures. Cold Spring Harbor Laboratory. doi: 10.1101/2022.02.02.22270328.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform LLC. doi: 10.21203/rs.2.12303/v2.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform LLC. doi: 10.21203/rs.2.12303/v4.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform LLC. doi: 10.21203/rs.2.12303/v5.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. Retrospective analysis of cases of intraoperative awareness in a large multi-hospital health system reported in the early postoperative period. Research Square Platform LLC. doi: 10.21203/rs.2.12303/v3.

Deis, A.S., Schnetz, M.P., Ibinson, J.W., & Vogt, K.M. Title: Retrospective analysis of reported cases of intraoperative awareness in a large multi-hospital health system. Research Square Platform LLC. doi: 10.21203/rs.2.12303/v1.

Norton, C.M., Ibinson, J.W., Pcola, S.J., Popov, V., Tremel, J.J., Reder, L.M., Fiez, J.A., & Vogt, K.M. Neutral auditory words immediately followed by painful electric shock show reduced next-day recollection. Cold Spring Harbor Laboratory. doi: 10.1101/2020.02.24.963165.

Vogt, K.M., Norton, C.M., Speer, L.E., Tremel, J.J., Ibinson, J.W., Reder, L.M., & Fiez, J.A. Memory for non-painful auditory items is influenced by whether they are experienced in a context involving painful electrical stimulation. Cold Spring Harbor Laboratory. doi: 10.1101/341891.

Vogt, K.M., Ibinson, J.W., Smith, C.T., Citro, A.T., Norton, C.M., Karim, H.T., Popov, V., Mahajan, A., Aizenstein, H.J., Reder, L.M., & Fiez, J.A. (2021). Midazolam and Ketamine Produce Distinct Neural Changes in Memory, Pain, and Fear Networks during Pain. In ANESTHESIOLOGY, 135(1), (pp. 69-82).Ovid Technologies (Wolters Kluwer Health).United States. doi: 10.1097/ALN.0000000000003774.

Vogt, K.M., Smith, C.T., Ibinson, J.W., & Fiez, J. (2021). Whole-brain network connectivity changes with midazolam sedation during task performance and periodic pain: A functional MRI study in healthy young adults. In ANESTHESIA AND ANALGESIA, 132(5S_SUPPL), (pp. 520-523).

Schnetz, M.P., Ibinson, J.W., Mahajan, A., Kaynar, A.M., & Vogt, K.M. (2020). Isolated intravenous anesthetic doses have small effects on BIS index during volatilebased anesthesia in surgical patients: A singleinstitution retrospective study. In ANESTHESIA AND ANALGESIA, 130, (pp. 741-743).

Vogt, K.M., Adams, P., Citro, A., Metro, D., & Sakai, T. (2020). Participation in a dedicated one-month Anesthesiology Professional Practice rotation as a PGY1 is associated with increased scholarly productivity during anesthesiology residency. In ANESTHESIA AND ANALGESIA, 130, (pp. 277-278).

Vogt, K.M., Smith, C.T., Mahajan, A., Ibinson, J.W., & Fiez, J. (2020). Neural correlates of memory formation during periodic acute pain with low-dose midazolam and ketamine: A randomized within-subject crossover functional MRI study in healthy young adult subjects. In ANESTHESIA AND ANALGESIA, 130, (pp. 397-399).

Schnetz, M.P., Dasgupta, P., Landsittel, D., Hochheiser, H., Vogt, K.M., Ibinson, J.W., Whitehurst, S., Mahajan, A., Danks, D., & Kaynar, A.M. (2019). RESPONSE TO INHALED ANESTHETICS MEASURED BY THE TRIPLE VARIABLE INDEX REVEALS POPULATION-SPECIFIC PATTERNS OF INTRAOPERATIVE HYPOTENSION EXPOSURE. In ANESTHESIA AND ANALGESIA, 128, (pp. 929-931).

Schnetz, M.P., Danks, D., Landsittel, D., Vogt, K.M., Ibinson, J.W., Whitehurst, S., & Kaynar, A.M. (2018). THE TRIPLE VARIABLE INDEX REVEALS SHARED PATTERNS OF PHYSIOLOGY THAT BROADEN THE UTILITY OF COMMON INTRAOPERATIVE MONITORING SYSTEMS TO CAPTURE RISK INFORMATION NOT IDENTIFIED BY ESTABLISHED MODELS. In ANESTHESIA AND ANALGESIA, 126(4), (pp. 667-670).

Smith, C.T., Vogt, K.M., & Ibinson, J.W. (2018). MIDAZOLAM SEDATION DURING THE PERIODIC EXPERIENCE OF PAIN DECREASES FUNCTIONAL CONNECTIVITY BOTH WITHIN AND BETWEEN BRAIN SYSTEMS FOR PAIN PROCESSING AND MEMORY ENCODING. In ANESTHESIA AND ANALGESIA, 126(4), (pp. 345-346).

Becker, C., Vogt, K., & Ibinson, J. (2017). Posterior cingulate connectivity changes during acute and chronic pain. In JOURNAL OF PAIN, 18(4), (p. S56).Elsevier BV. doi: 10.1016/j.jpain.2017.02.219.

Becker, C.J., Vogt, K.M., & Ibinson, J.W. (2016). VALIDATION OF INSULA CONNECTIVITY CHANGES DURING PAIN. In ANESTHESIA AND ANALGESIA, 122.

Vogt, K.M., Ibinson, J.W., Tremel, J., Reder, L.M., & Fiez, J.A. (2016). ACUTE EXPERIMENTAL PAIN AFFECTS LONG-TERM MEMORY OF AUDITORY CUES PRESENTED DURING SEDATION WITH DEXMEDETOMIDINE AND MIDAZOLAM. In ANESTHESIA AND ANALGESIA, 122.

Becker, C., Vogt, K., & Ibinson, J. (2015). The insula's functional connectivity to the default mode network is uniquely altered by pain perception. In JOURNAL OF PAIN, 16(4), (p. S54).Elsevier BV. doi: 10.1016/j.jpain.2015.01.231.

Ibinson, J., Gach, M., & Vogt, K. (2015). A comparison of the BOLD and ASL temporal responses during functional imaging of pain. In JOURNAL OF PAIN, 16(4), (p. S53).Elsevier BV. doi: 10.1016/j.jpain.2015.01.226.

Ibinson, J., & Vogt, K. (2014). Effect of anti-correlations on statistical comparisons between pain task and resting fcMRI datasets. In JOURNAL OF PAIN, 15(4), (p. S58).Elsevier BV. doi: 10.1016/j.jpain.2014.01.239.

Ibinson, J., & Vogt, K. (2014). fcMRI maps during pain tasks vary based on the inclusion of paradigm modeling in analysis. In JOURNAL OF PAIN, 15(4), (p. S57).Elsevier BV. doi: 10.1016/j.jpain.2014.01.235.

Vogt, K.M., & Ibinson, J.W. (2014). THE POSTERIOR INSULA REVEALS PAIN VS REST FUNCTIONAL CONNECTIVITY DIFFERENCES NOT PRESENT WITH THE ANTERIOR INSULA. In ANESTHESIA AND ANALGESIA, 118, (p. S202).