headshot

Bryan Brown

Associate Professor
Assistant Professor
McGowan Institute for Regenerative Medicine Bioengineering Department

about

(2014) Educator Award, Tissue Engineering and Regenerative Medicine International Society.

(2013) Best Basic Science Research Poster (Veterinary Orthopedic Society 2013 Annual meeting).

(2013) Building Interdisciplinary Research Careers in Women's Health Scholar (NIH, Office of Research on Women's Health).

(2011) Second Place, Elevator Pitch Contest (3 Rivers Venture Fair - University Technology Showcase).

(2010) Carnegie Science Award, Carnegie Science Center.

(2010) Young Investigator Award (Wake Forest Institute for Regenerative Medicine and Tissue Engineering and Regenerative Medicine International Society aka. TERMIS).

(2010) McGowan Institute for Regenerative Medicine Trainee Career Advancement Program Scholarship (McGowan Institute for Regenerative Medicine).

(2009) STAR Award (Student Travel Achievement Award), Society for Biomaterials.

(2009) National Research Service Award (F31) (National Institutes of Health).

(2009) East Asia and Pacific Fellowship (National Science Foundation and Japan Society for the Promotion of Science).

(2008) 50 Best Abstracts Award (Tissue Engineering and Regenerative Medicine International Society--TERMIS).

(2007) McGowan Institute for Regenerative Medicine Trainee Career Advancement Program Scholarship.

(2007) Outstanding Teaching Assistant Award Nominee (University of Pittsburgh, Dept. of Bioengineering).

(2007) Student Travel Award (Tissue Engineering and Regenerative Medicine International Society).

(2006) Bevier Fellowship (University of Pittsburgh).

(2001 - 2005) Engineering Honors Scholarship (University of Pittsburgh, Swanson School of Engineering).

(2001 - 2005) Honors College Scholarship (University of Pittsburgh Honors College).

Postdoctoral Training in Biomedical Engineering/Clinical Sciences, Cornell University, 2010 - 2011

PhD, Bioengineering, University of Pittsburgh, 2006 - 2010

Postdoctoral Training in Mandarin, Peking University, 2005 - 2006

BS, Mechanical Engineering, University of Pittsburgh, 2001 - 2005

Cercone, M., Brown, B.N., Stahl, E.C., Mitchell, L.M., Fortier, L.A., Mohammed, H.O., & Ducharme, N.G. (2021). An Exploratory Study into the Implantation of Arytenoid Cartilage Scaffold in the Horse. TISSUE ENGINEERING PART A, 27(3-4), 165-176.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2019.0295.

Haschak, M., LoPresti, S., Stahl, E., Dash, S., Popovich, B., & Brown, B.N. (2021). Macrophage phenotype and function are dependent upon the composition and biomechanics of the local cardiac tissue microenvironment. AGING-US, 13(13), 16938-16956.Impact Journals, LLC. doi: 10.18632/aging.203054.

Buckenmeyer, M.J., Meder, T.J., Prest, T.A., & Brown, B.N. (2020). Decellularization techniques and their applications for the repair and regeneration of the nervous system. METHODS, 171, 41-61.Elsevier BV. doi: 10.1016/j.ymeth.2019.07.023.

Hachim, D., LoPresti, S.T., Rege, R.D., Umeda, Y., Iftikhar, A., Nolfi, A.L., Skillen, C.D., & Brown, B.N. (2020). Distinct macrophage populations and phenotypes associated with IL-4 mediated immunomodulation at the host implant interface. BIOMATERIALS SCIENCE, 8(20), 5751-5762.Royal Society of Chemistry (RSC). doi: 10.1039/d0bm00568a.

Nolfi, A.L., Behun, M.N., Yates, C.C., Brown, B.N., & Kulkarni, M. (2020). Beyond Growth Factors: Macrophage-Centric Strategies for Angiogenesis. Current Pathobiology Reports, 8(4), 111-120.Springer Science and Business Media LLC. doi: 10.1007/s40139-020-00215-9.

Stahl, E.C., Delgado, E.R., Alencastro, F., LoPresti, S.T., Wilkinson, P.D., Roy, N., Haschak, M.J., Skillen, C.D., Monga, S.P., Duncan, A.W., & Brown, B.N. (2020). Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. AMERICAN JOURNAL OF PATHOLOGY, 190(2), 372-387.Elsevier BV. doi: 10.1016/j.ajpath.2019.10.016.

Hachim, D., Iftikhar, A., LoPresti, S.T., Nolfi, A.L., Ravichandar, S., Skillen, C.D., & Brown, B.N. (2019). Distinct release strategies are required to modulate macrophage phenotype in young versus aged animals. JOURNAL OF CONTROLLED RELEASE, 305, 65-74.Elsevier BV. doi: 10.1016/j.jconrel.2019.05.020.

LoPresti, S.T., Popovic, B., Kulkarni, M., Skillen, C.D., & Brown, B.N. (2019). Free radical-decellularized tissue promotes enhanced antioxidant and anti-inflammatory macrophage response. BIOMATERIALS, 222, 119376.Elsevier BV. doi: 10.1016/j.biomaterials.2019.119376.

Mostafaei, A., De Vecchis, P.R., Buckenmeyer, M.J., Wasule, S.R., Brown, B.N., & Chmielus, M. (2019). Microstructural evolution and resulting properties of differently sintered and heat-treated binder-jet 3D-printed Stellite 6. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 102, 276-288.Elsevier BV. doi: 10.1016/j.msec.2019.04.011.

Sun, A.X., Prest, T.A., Fowler, J.R., Brick, R.M., Gloss, K.M., Li, X., DeHart, M., Shen, H., Yang, G., Brown, B.N., Alexander, P.G., & Tuan, R.S. (2019). Conduits harnessing spatially controlled cell-secreted neurotrophic factors improve peripheral nerve regeneration. BIOMATERIALS, 203, 86-95.Elsevier BV. doi: 10.1016/j.biomaterials.2019.01.038.

Almarza, A.J., Brown, B.N., Arzi, B., Angelo, D.F., Chung, W., Badylak, S.F., & Detamore, M. (2018). Preclinical Animal Models for Temporomandibular Joint Tissue Engineering. TISSUE ENGINEERING PART B-REVIEWS, 24(3), 171-178.Mary Ann Liebert Inc. doi: 10.1089/ten.teb.2017.0341.

Hachim, D., & Brown, B.N. (2018). Surface modification of polypropylene for enhanced layer-by-layer deposition of polyelectrolytes. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 106(7), 2078-2085.Wiley. doi: 10.1002/jbm.a.36405.

Lowe, J., Bansal, R., Badylak, S.F., Brown, B.N., Chung, W.L., & Almarza, A.J. (2018). Properties of the Temporomandibular Joint in Growing Pigs. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 140(7).ASME International. doi: 10.1115/1.4039624.

Prest, T.A., Yeager, E., LoPresti, S.T., Zygelyte, E., Martin, M.J., Dong, L., Gibson, A., Olutoye, O.O., Brown, B.N., & Cheetham, J. (2018). Nerve-specific, xenogeneic extracellular matrix hydrogel promotes recovery following peripheral nerve injury. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 106(2), 450-459.Wiley. doi: 10.1002/jbm.a.36235.

Stahl, E.C., Bonvillain, R.W., Skillen, C.D., Burger, B.L., Hara, H., Lee, W., Trygg, C.B., Didier, P.J., Grasperge, B.F., Pashos, N.C., Bunnell, B.A., Bianchi, J., Ayares, D.L., Guthrie, K.I., Brown, B.N., & Petersen, T.H. (2018). Evaluation of the host immune response to decellularized lung scaffolds derived from alpha-Gal knockout pigs in a non-human primate model. BIOMATERIALS, 187, 93-104.Elsevier BV. doi: 10.1016/j.biomaterials.2018.09.038.

Stahl, E.C., Haschak, M.J., Popovic, B., & Brown, B.N. (2018). Macrophages in the Aging Liver and Age-Related Liver Disease. FRONTIERS IN IMMUNOLOGY, 9(NOV), 2795.Frontiers Media SA. doi: 10.3389/fimmu.2018.02795.

Brown, B.N., Buckenmeyer, M.J., & Prest, T.A. (2017). Preparation of Decellularized Biological Scaffolds for 3D Cell Culture. Methods Mol Biol, 1612, 15-27.Springer New York. doi: 10.1007/978-1-4939-7021-6_2.

Brown, B.N., Haschak, M.J., Lopresti, S.T., & Stahl, E.C. (2017). Effects of age-related shifts in cellular function and local microenvironment upon the innate immune response to implants. SEMINARS IN IMMUNOLOGY, 29, 24-32.Elsevier BV. doi: 10.1016/j.smim.2017.05.001.

Hachim, D., LoPresti, S.T., Yates, C.C., & Brown, B.N. (2017). Shifts in macrophage phenotype at the biomaterial interface via IL-4 eluting coatings are associated with improved implant integration. BIOMATERIALS, 112, 95-107.Elsevier BV. doi: 10.1016/j.biomaterials.2016.10.019.

Hachim, D., Wang, N., Lopresti, S.T., Stahl, E.C., Umeda, Y.U., Rege, R.D., Carey, S.T., Mani, D., & Brown, B.N. (2017). Effects of aging upon the host response to implants. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 105(5), 1281-1292.Wiley. doi: 10.1002/jbm.a.36013.

Huleihel, L., Bartolacci, J.G., Dziki, J.L., Vorobyov, T., Arnold, B., Scarritt, M.E., Molina, C.P., LoPresti, S.T., Brown, B.N., Naranjo, J.D., & Badylak, S.F. (2017). Matrix-Bound Nanovesicles Recapitulate Extracellular Matrix Effects on Macrophage Phenotype. TISSUE ENGINEERING PART A, 23(21-22), 1283-1294.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2017.0102.

Huleihel, L., Dziki, J.L., Bartolacci, J.G., Rausch, T., Scarritt, M.E., Cramer, M.C., Vorobyov, T., LoPresti, S.T., Swineheart, I.T., White, L.J., Brown, B.N., & Badylak, S.F. (2017). Macrophage phenotype in response to ECM bioscaffolds. SEMINARS IN IMMUNOLOGY, 29, 2-13.Elsevier BV. doi: 10.1016/j.smim.2017.04.004.

Brown, B.N., & Badylak, S.F. (2016). Extracellular Matrix as an Inductive Scaffold for Functional Tissue Reconstruction. In Translating Regenerative Medicine to the Clinic. (pp. 11-29).Elsevier. doi: 10.1016/b978-0-12-800548-4.00002-4.

Hoffman, B., Martin, M., Brown, B.N., Bonassar, L.J., & Cheetham, J. (2016). Biomechanical and Biochemical Characterization of Porcine Tracheal Cartilage. LARYNGOSCOPE, 126(10), E325-E331.Wiley. doi: 10.1002/lary.25861.

Nolfi, A.L., Brown, B.N., Liang, R., Palcsey, S.L., Bonidie, M.J., Abramowitch, S.D., & Moalli, P.A. (2016). Host response to synthetic mesh in women with mesh complications. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 215(2), 206.e1-206.e8.Elsevier BV. doi: 10.1016/j.ajog.2016.04.008.

Brown, B.N., Mani, D., Nolfi, A.L., Liang, R., Abramowitch, S.D., & Moalli, P.A. (2015). Characterization of the host inflammatory response following implantation of prolapse mesh in rhesus macaque. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 213(5), 668.e1-668.10.Elsevier BV. doi: 10.1016/j.ajog.2015.08.002.

Hartman, R.A., Yurube, T., Ngo, K., Merzlak, N.E., Debski, R.E., Brown, B.N., Kang, J.D., & Sowa, G.A. (2015). Biological Responses to Flexion/Extension in Spinal Segments Ex-Vivo. JOURNAL OF ORTHOPAEDIC RESEARCH, 33(8), 1255-1264.Wiley. doi: 10.1002/jor.22900.

Lopresti, S.T., & Brown, B.N. (2015). Host Response to Naturally Derived Biomaterials. In Host Response to Biomaterials. (pp. 53-79).Elsevier. doi: 10.1016/b978-0-12-800196-7.00004-9.

Rao, J., Brown, B.N., Weinbaum, J.S., Ofstun, E.L., Makaroun, M.S., Humphrey, J.D., & Vorp, D.A. (2015). Distinct macrophage phenotype and collagen organization within the intraluminal thrombus of abdominal aortic aneurysm. JOURNAL OF VASCULAR SURGERY, 62(3), 585-593.Elsevier BV. doi: 10.1016/j.jvs.2014.11.086.

Sawkins, M.J., Mistry, P., Brown, B.N., Shakesheff, K.M., Bonassar, L.J., & Yang, J. (2015). Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair. Biofabrication, 7(3), 035004.IOP Publishing. doi: 10.1088/1758-5090/7/3/035004.

Stahl, E.C., & Brown, B.N. (2015). Cell Therapy Strategies to Combat Immunosenescence. ORGANOGENESIS, 11(4), 159-172.Informa UK Limited. doi: 10.1080/15476278.2015.1120046.

Wolf, M.T., Vodovotz, Y., Tottey, S., Brown, B.N., & Badylak, S.F. (2015). Predicting In Vivo Responses to Biomaterials via Combined In Vitro and In Silico Analysis. TISSUE ENGINEERING PART C-METHODS, 21(2), 148-159.Mary Ann Liebert Inc. doi: 10.1089/ten.tec.2014.0167.

Brown, B.N., & Badylak, S.F. (2014). The Role of the Host Immune Response in Tissue Engineering and Regenerative Medicine. In Principles of Tissue Engineering. (pp. 497-509).Elsevier. doi: 10.1016/b978-0-12-398358-9.00025-2.

Brown, B.N., & Badylak, S.F. (2014). Extracellular matrix as an inductive scaffold for functional tissue reconstruction. TRANSLATIONAL RESEARCH, 163(4), 268-285.Elsevier BV. doi: 10.1016/j.trsl.2013.11.003.

Brown, B.N., & Badylak, S.F. (2014). Biocompatibility and Immune Response to Biomaterials. In Regenerative Medicine Applications in Organ Transplantation. (pp. 151-162).Elsevier. doi: 10.1016/b978-0-12-398523-1.00011-2.

Brown, B.N., Sicari, B.M., & Badylak, S.E. (2014). Rethinking regenerative medicine: a macropnage-centered approach. FRONTIERS IN IMMUNOLOGY, 5(NOV), 510.Frontiers Media SA. doi: 10.3389/fimmu.2014.00510.

Brown, B.N., Siebenlist, N.J., Cheetham, J., Ducharme, N.G., Rawlinson, J.J., & Bonassar, L.J. (2014). Computed Tomography-Guided Tissue Engineering of Upper Airway Cartilage. TISSUE ENGINEERING PART C-METHODS, 20(6), 506-513.Mary Ann Liebert Inc. doi: 10.1089/ten.tec.2013.0216.

Grevemeyer, B., Bogdanovic, L., Canton, S., Jean, G.S., Cercone, M., Ducharme, N.G., & Brown, B.N. (2014). Regenerative Medicine Approach to Reconstruction of the Equine Upper Airway. TISSUE ENGINEERING PART A, 20(7-8), 1213-1221.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2013.0217.

Moalli, P., Brown, B., Reitman, M.T.F., & Nager, C.W. (2014). Polypropylene mesh: evidence for lack of carcinogenicity. INTERNATIONAL UROGYNECOLOGY JOURNAL, 25(5), 573-576.Springer Science and Business Media LLC. doi: 10.1007/s00192-014-2343-8.

Sanz, A.F., Hoppo, T., Witteman, B.P., Brown, B.N., Gilbert, T.W., Badylak, S.F., Jobe, B.A., & Nieponice, A. (2014). In Vivo Assessment of a Biological Occluder for NOTES Gastrotomy Closure. SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES, 24(4), 322-326.Ovid Technologies (Wolters Kluwer Health). doi: 10.1097/SLE.0b013e3182a1c31b.

Wolf, M.T., Dearth, C.L., Ranallo, C.A., LoPresti, S.T., Carey, L.E., Daly, K.A., Brown, B.N., & Badylak, S.F. (2014). Macrophage polarization in response to ECM coated polypropylene mesh. BIOMATERIALS, 35(25), 6838-6849.Elsevier BV. doi: 10.1016/j.biomaterials.2014.04.115.

Badylak, S.F., Brown, B.N., & Gilbert, T.W. (2013). Tissue Engineering with Decellularized Tissues. In Biomaterials Science. (pp. 1316-1331).Elsevier. doi: 10.1016/b978-0-08-087780-8.00140-6.

Brown, B.N., & Badylak, S.F. (2013). Expanded applications, shifting paradigms and an improved understanding of host-biomaterial interactions. ACTA BIOMATERIALIA, 9(2), 4948-4955.Elsevier BV. doi: 10.1016/j.actbio.2012.10.025.

Puetzer, J.L., Brown, B.N., Ballyns, J.J., & Bonassar, L.J. (2013). The Effect of IGF-I on Anatomically Shaped Tissue-Engineered Menisci. TISSUE ENGINEERING PART A, 19(11-12), 1443-1450.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2012.0645.

Reiffel, A.J., Kafka, C., Hernandez, K.A., Popa, S., Perez, J.L., Zhou, S., Pramanik, S., Brown, B.N., Ryu, W.S., Bonassar, L.J., & Spector, J.A. (2013). High-Fidelity Tissue Engineering of Patient-Specific Auricles for Reconstruction of Pediatric Microtia and Other Auricular Deformities. PLOS ONE, 8(2), e56506.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0056506.

Remlinger, N.T., Gilbert, T.W., Yoshida, M., Guest, B.N., Hashizume, R., Weaver, M.L., Wagner, W.R., Brown, B.N., Tobita, K., & Wearden, P.D. (2013). Urinary bladder matrix promotes site appropriate tissue formation following right ventricle outflow tract repair. ORGANOGENESIS, 9(3), 149-160.Informa UK Limited. doi: 10.4161/org.25394.

Turner, N.J., Pezzone, M.A., Brown, B.N., & Badylak, S.F. (2013). Quantitative multispectral imaging of Herovici's polychrome for the assessment of collagen content and tissue remodelling. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 7(2), 139-148.Wiley. doi: 10.1002/term.508.

Udpa, N., Iyer, S.R., Rajoria, R., Breyer, K.E., Valentine, H., Singh, B., McDonough, S.P., Brown, B.N., Bonassar, L.J., & Gao, Y. (2013). Effects of Chitosan Coatings on Polypropylene Mesh for Implantation in a Rat Abdominal Wall Model. TISSUE ENGINEERING PART A, 19(23-24), 2713-2723.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2012.0739.

Wang, J.Y., Liou, A.K.F., Ren, Z.H., Zhang, L., Brown, B.N., Cui, X.T., Badylak, S.F., Cai, Y.N., Guan, Y.Q., Leak, R.K., Chen, J., Ji, X., & Chen, L. (2013). Neurorestorative Effect of Urinary Bladder Matrix-Mediated Neural Stem Cell Transplantation Following Traumatic Brain Injury in Rats. CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS, 12(3), 413-425.Bentham Science Publishers Ltd. doi: 10.2174/1871527311312030014.

Zhang, L., Zhang, F., Weng, Z., Brown, B.N., Yan, H., Ma, X.M., Vosler, P.S., Badylak, S.F., Dixon, C.E., Cui, X.T., & Chen, J. (2013). Effect of an Inductive Hydrogel Composed of Urinary Bladder Matrix Upon Functional Recovery Following Traumatic Brain Injury. TISSUE ENGINEERING PART A, 19(17-18), 1909-1918.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2012.0622.

Ahmed, T., Marcal, H., Johnson, S., Brown, B.N., & Foster, L.J.R. (2012). Coalescence of Extracellular Matrix (ECM) from Porcine Urinary Bladder (UBM) with a Laser-Activated Chitosan-Based Surgical Adhesive. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 23(12), 1521-1538.Informa UK Limited. doi: 10.1163/092050611X585431.

Brown, B.N., Chung, W.L., Almarza, A.J., Pavlick, M.D., Reppas, S.N., Ochs, M.W., Russell, A.J., & Badylak, S.F. (2012). Inductive, Scaffold-Based, Regenerative Medicine Approach to Reconstruction of the Temporomandibular Joint Disk. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 70(11), 2656-2668.Elsevier BV. doi: 10.1016/j.joms.2011.12.030.

Brown, B.N., Londono, R., Tottey, S., Zhang, L., Kukla, K.A., Wolf, M.T., Daly, K.A., Reing, J.E., & Badylak, S.F. (2012). Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials. ACTA BIOMATERIALIA, 8(3), 978-987.Elsevier BV. doi: 10.1016/j.actbio.2011.11.031.

Brown, B.N., Londono, R., Tottey, S., Zhang, L., Kukla, K.A., Wolf, M.T., Daly, K.A., Reing, J.E., & Badylak, S.F. (2012). Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials (vol 8, pg 978, 2012). ACTA BIOMATERIALIA, 8(7), 2871.Elsevier BV. doi: 10.1016/j.actbio.2012.03.005.

Brown, B.N., Ratner, B.D., Goodman, S.B., Amar, S., & Badylak, S.F. (2012). Macrophage polarization: An opportunity for improved outcomes in and regenerative medicine. BIOMATERIALS, 33(15), 3792-3802.Elsevier BV. doi: 10.1016/j.biomaterials.2012.02.034.

Daly, K.A., Liu, S., Agrawal, V., Brown, B.N., Huber, A., Johnson, S.A., Reing, J., Sicari, B., Wolf, M., Zhang, X., & Badylak, S.F. (2012). The Host Response to Endotoxin-Contaminated Dermal Matrix. TISSUE ENGINEERING PART A, 18(11-12), 1293-1303.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2011.0597.

Daly, K.A., Liu, S., Agrawal, V., Brown, B.N., Johnson, S.A., Medberry, C.J., & Badylak, S.F. (2012). Damage associated molecular patterns within xenogeneic biologic scaffolds and their effects on host remodeling. BIOMATERIALS, 33(1), 91-101.Elsevier BV. doi: 10.1016/j.biomaterials.2011.09.040.

Badylak, S.F., Brown, B.N., Gilbert, T.W., Daly, K.A., Huber, A., & Turner, N.J. (2011). Biologic scaffolds for constructive tissue remodeling. Biomaterials, 32(1), 316-319.Elsevier BV. doi: 10.1016/j.biomaterials.2010.09.018.

Barnes, C.A., Brison, J., Michel, R., Brown, B.N., Castner, D.G., Badylak, S.F., & Ratner, B.D. (2011). The surface molecular functionality of decellularized extracellular matrices. BIOMATERIALS, 32(1), 137-143.Elsevier BV. doi: 10.1016/j.biomaterials.2010.09.007.

Brown, B.N., Chung, W.L., Pavlick, M., Reppas, S., Ochs, M.W., Russell, A.J., & Badylak, S.F. (2011). Extracellular Matrix as an Inductive Template for Temporomandibular Joint Meniscus Reconstruction: A Pilot Study. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 69(12), E488-E505.Elsevier BV. doi: 10.1016/j.joms.2011.02.130.

Brown, B.N., Freund, J.M., Han, L., Rubin, J.P., Reing, J.E., Jeffries, E.M., Wolf, M.T., Tottey, S., Barnes, C.A., Ratner, B.D., & Badylak, S.F. (2011). Comparison of Three Methods for the Derivation of a Biologic Scaffold Composed of Adipose Tissue Extracellular Matrix. TISSUE ENGINEERING PART C-METHODS, 17(4), 411-421.Mary Ann Liebert Inc. doi: 10.1089/ten.tec.2010.0342.

Brown, B.N., Price, I.M., Toapanta, F.R., DeAlmeida, D.R., Wiley, C.A., Ross, T.M., Oury, T.D., & Vodovotz, Y. (2011). An agent-based model of inflammation and fibrosis following particulate exposure in the lung. MATHEMATICAL BIOSCIENCES, 231(2), 186-196.Elsevier BV. doi: 10.1016/j.mbs.2011.03.005.

Brown, B.N., Barnes, C.A., Kasick, R.T., Michel, R., Gilbert, T.W., Beer-Stolz, D., Castner, D.G., Ratner, B., & Badylak, S.F. (2010). Surface characterization of extracellular matrix scaffolds. BIOMATERIALS, 31(3), 428-437.Elsevier BV. doi: 10.1016/j.biomaterials.2009.09.061.

Reing, J.E., Brown, B.N., Daly, K.A., Freund, J.M., Gilbert, T.W., Hsiong, S.X., Huber, A., Kullas, K.E., Tottey, S., Wolf, M.T., & Badylak, S.F. (2010). The effects of processing methods upon mechanical and biologic properties of porcine dermal extracellular matrix scaffolds. BIOMATERIALS, 31(33), 8626-8633.Elsevier BV. doi: 10.1016/j.biomaterials.2010.07.083.

Agrawal, V., Brown, B.N., Beattie, A.J., Gilbert, T.W., & Badylak, S.F. (2009). Evidence of innervation following extracellular matrix scaffold-mediated remodelling of muscular tissues. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 3(8), 590-600.Wiley. doi: 10.1002/term.200.

Brown, B.N., Valentin, J.E., Stewart-Akers, A.M., McCabe, G.P., & Badylak, S.F. (2009). Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component. BIOMATERIALS, 30(8), 1482-1491.Elsevier BV. doi: 10.1016/j.biomaterials.2008.11.040.

Brown, B., Lindberg, K., Reing, J., Stolz, D.B., & Badylak, S.F. (2006). The basement membrane component of biologic scaffolds derived from extracellular matrix. TISSUE ENGINEERING, 12(3), 519-526.Mary Ann Liebert Inc. doi: 10.1089/ten.2006.12.519.

Brown, B., Lindberg, K., Reing, J., Stolz, D.B., & Badylak, S.F. (2006). The basement membrane component of biologic scaffolds derived from extracellular matrix. Tissue Engineering, 12(3), 519-526. doi: 10.1089/ten.2006.12.519.

Brown, B.N., Mani, D., Nolfi, A.L., & Moalli, P. (2014). IMPACT OF PROLAPSE MESH PROPERTIES ON THE HOST INFLAMMATORY RESPONSE. 2014 AUGS/IUGA Scientific Meeting.Washington, DC.

Nolfi, A.L., Brown, B., Palcsey, S.L., Turner, L.C., & Moalli, P. (2014). AN M1 PRO-INFLAMMATORY PROFILE PERSISTS IN TISSUE EXCISED FROM WOMEN WITH MESH COMPLICATIONS YEARS AFTER MESH INSERTION. 2014 AUGS/IUGA Scientific Meeting.Washington, DC.

Sawkins, M.J., Brown, B.N., Bonassar, L.J., Rose, F.R.A.J., & Shakesheff, K.M. (2011). Bioprinting as a tool for osteochondral tissue engineering. In European Cells and Materials, 22(SUPPL.3), (p. 51).

Research interests

Host Response To Biomaterials
Macrophage Biology
nerve regeneration
pelvic floor
Regenerative Medicine
surgical mesh
temporomandibular joint
Tissue Engineering
Womens Health