headshot of Yadong Wang

Yadong Wang

Professor
Bio materials Foundry Bioengineering Department Mechanical Engineering & Materials Science

about

(2014) Elected Fellow, AIMBE.

(2013) Dutch Heart Foundation Lecture, International Symposium on Vascular Tissue Engineering, Leiden, The Netherlands.

(2012) American Heart Association Established Investigator Award.

(2012) Randall Family Big Idea Competition, 1st Place Winner (Mentor).

(2012) CMU Summit New Venture Competition, 1st Place Winner (Mentor).

(2008) Best Undergraduate Advisor Award, BMES Georgia Tech Chapter.

(2007) Member, Advisory Board, Lifeboat Foundation.

(2007) American Heart Association Scientist Development Award.

(2007) Best Professor Award, BMES Georgia Tech Chapter.

(2007) SAIC Outstanding Research Paper Award.

(2007) Hunter Chair Lecture, Clemson University.

(2005) Finalist, the INDEX: Award, Copenhagen, Denmark.

(1998 - 1999) Franklin Veatch Memorial Scholarship, Stanford University.

PhD, Chemistry, Stanford University, 1999

M.S., Chemistry, Kansas State University, 1995

Ângelo, D.F., Monje, F.G., González-García, R., Little, C.B., Mónico, L., Pinho, M., Santos, F.A., Carrapiço, B., Gonçalves, S.C., Morouço, P., Alves, N., Moura, C., Wang, Y., Jeffries, E., Gao, J., Sousa, R., Neto, L.L., Caldeira, D., & Salvado, F. (2017). Bioengineered Temporomandibular Joint Disk Implants: Study Protocol for a Two-Phase Exploratory Randomized Preclinical Pilot Trial in 18 Black Merino Sheep (TEMPOJIMS). JMIR Res Protoc, 6(3), e37.JMIR Publications Inc. doi: 10.2196/resprot.6779.

Awada, H.K., Long, D.W., Wang, Z., Hwang, M.P., Kim, K., & Wang, Y. (2017). A single injection of protein-loaded coacervate-gel significantly improves cardiac function post infarction. BIOMATERIALS, 125, 65-80.Elsevier BV. doi: 10.1016/j.biomaterials.2017.02.020.

Long, D.W., Johnson, N.R., Jeffries, E.M., Hara, H., & Wang, Y. (2017). Controlled delivery of platelet-derived proteins enhances porcine wound healing. JOURNAL OF CONTROLLED RELEASE, 253, 73-81.Elsevier BV. doi: 10.1016/j.jconrel.2017.03.021.

Awada, H.K., Hwang, M.P., & Wang, Y. (2016). Towards comprehensive cardiac repair and regeneration after myocardial infarction: Aspects to consider and proteins to deliver. BIOMATERIALS, 82, 94-112.Elsevier BV. doi: 10.1016/j.biomaterials.2015.12.025.

Ding, X., Gao, J., Wang, Z., Awada, H., & Wang, Y. (2016). A shear-thinning hydrogel that extends in vivo bioactivity of FGF2. BIOMATERIALS, 111, 80-89.Elsevier BV. doi: 10.1016/j.biomaterials.2016.09.026.

Awada, H.K., Johnson, N.R., & Wang, Y. (2015). Sequential delivery of angiogenic growth factors improves revascularization and heart function after myocardial infarction. JOURNAL OF CONTROLLED RELEASE, 207, 7-17.Elsevier BV. doi: 10.1016/j.jconrel.2015.03.034.

Chen, W.C.W., Lee, B.G., Park, D.W., Kim, K., Chu, H., Kim, K., Huard, J., & Wang, Y. (2015). Controlled dual delivery of fibroblast growth factor-2 and Interleukin-10 by heparin-based coacervate synergistically enhances ischemic heart repair. BIOMATERIALS, 72, 138-151.Elsevier BV. doi: 10.1016/j.biomaterials.2015.08.050.

Jeffries, E.M., Allen, R.A., Gao, J., Pesce, M., & Wang, Y. (2015). Highly elastic and suturable electrospun poly(glycerol sebacate) fibrous scaffolds. ACTA BIOMATERIALIA, 18, 30-39.Elsevier BV. doi: 10.1016/j.actbio.2015.02.005.

Johnson, N.R., & Wang, Y. (2015). Drug delivery systems for wound healing. Curr Pharm Biotechnol, 16(7), 621-629.Bentham Science Publishers Ltd. doi: 10.2174/1389201016666150206113720.

Rauck, B.M., Novosat, T.L., Oudega, M., & Wang, Y. (2015). Biocompatibility of a coacervate-based controlled release system for protein delivery to the injured spinal cord. ACTA BIOMATERIALIA, 11(C), 204-211.Elsevier BV. doi: 10.1016/j.actbio.2014.09.037.

Xiao, J., Wang, Y., Bellusci, S., & Li, X. (2015). Pharmacological application of growth factors: basic and clinical. Biomed Res Int, 2015, 141794.Hindawi Limited. doi: 10.1155/2015/141794.

Allen, R.A., Wu, W., Yao, M., Dutta, D., Duan, X., Bachman, T.N., Champion, H.C., Stolz, D.B., Robertson, A.M., Kim, K., Isenberg, J.S., & Wang, Y. (2014). Nerve regeneration and elastin formation within poly(glycerol sebacate)-based synthetic arterial grafts one-year post-implantation in a rat model. BIOMATERIALS, 35(1), 165-173.Elsevier BV. doi: 10.1016/j.biomaterials.2013.09.081.

Awada, H.K., Johnson, N.R., & Wang, Y. (2014). Dual Delivery of Vascular Endothelial Growth Factor and Hepatocyte Growth Factor Coacervate Displays Strong Angiogenic Effects. MACROMOLECULAR BIOSCIENCE, 14(5), 679-686.Wiley. doi: 10.1002/mabi.201300486.

Bae, H., Chu, H., Edalat, F., Cha, J.M., Sant, S., Kashyap, A., Ahari, A.F., Kwon, C.H., Nichol, J.W., Manoucheri, S., Zamanian, B., Wang, Y., & Khademhosseini, A. (2014). Development of functional biomaterials with micro- and nanoscale technologies for tissue engineering and drug delivery applications. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 8(1), 1-14.Hindawi Limited. doi: 10.1002/term.1494.

Bi, X., You, Z., Gao, J., Fan, X., & Wang, Y. (2014). A functional polyester carrying free hydroxyl groups promotes the mineralization of osteoblast and human mesenchymal stem cell extracellular matrix. ACTA BIOMATERIALIA, 10(6), 2814-2823.Elsevier BV. doi: 10.1016/j.actbio.2014.02.018.

Deng, Y., Bi, X., Zhou, H., You, Z., Wang, Y., Gu, P., & Fan, X. (2014). REPAIR OF CRITICAL-SIZED BONE DEFECTS WITH ANTI-MIR-31-EXPRESSING BONE MARROW STROMAL STEM CELLS AND POLY(GLYCEROL SEBACATE) SCAFFOLDS. EUROPEAN CELLS & MATERIALS, 27, 13-25.European Cells and Materials. doi: 10.22203/eCM.v027a02.

Johnson, N.R., Ambe, T., & Wang, Y. (2014). Lysine-based polycation:heparin coacervate for controlled protein delivery. ACTA BIOMATERIALIA, 10(1), 40-46.Elsevier BV. doi: 10.1016/j.actbio.2013.09.012.

Rauck, B.M., Friberg, T.R., Mendez, C.A.M., Park, D., Shah, V., Bilonick, R.A., & Wang, Y. (2014). Biocompatible Reverse Thermal Gel Sustains the Release of Intravitreal Bevacizumab In Vivo. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(1), 469-476.Association for Research in Vision and Ophthalmology (ARVO). doi: 10.1167/iovs.13-13120.

Ritfeld, G.J., Rauck, B.M., Novosat, T.L., Park, D., Patel, P., Roos, R.A.C., Wang, Y., & Oudega, M. (2014). The effect of a polyurethane-based reverse thermal gel on bone marrow stromal cell transplant survival and spinal cord repair. BIOMATERIALS, 35(6), 1924-1931.Elsevier BV. doi: 10.1016/j.biomaterials.2013.11.062.

Zaky, S.H., Hangadora, C.K., Tudares, M.A., Gao, J., Jensen, A., Wang, Y., Sfeir, C., & Almarza, A.J. (2014). Poly (glycerol sebacate) elastomer supports osteogenic phenotype for bone engineering applications. BIOMEDICAL MATERIALS, 9(2), 025003.IOP Publishing. doi: 10.1088/1748-6041/9/2/025003.

Zaky, S.H., Lee, K.W., Gao, J., Jensen, A., Close, J., Wang, Y., Almarza, A.J., & Sfeir, C. (2014). Poly(Glycerol Sebacate) Elastomer: A Novel Material for Mechanically Loaded Bone Regeneration. TISSUE ENGINEERING PART A, 20(1-2), 45-53.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2013.0172.

Chu, H., Chen, C.W., Huard, J., & Wang, Y. (2013). The effect of a heparin-based coacervate of fibroblast growth factor-2 on scarring in the infarcted myocardium. BIOMATERIALS, 34(6), 1747-1756.Elsevier BV. doi: 10.1016/j.biomaterials.2012.11.019.

Dutta, D., Lee, K.W., Allen, R.A., Wang, Y., Brigham, J.C., & Kim, K. (2013). NON-INVASIVE ASSESSMENT OF ELASTIC MODULUS OF ARTERIAL CONSTRUCTS DURING CELL CULTURE USING ULTRASOUND ELASTICITY IMAGING. ULTRASOUND IN MEDICINE AND BIOLOGY, 39(11), 2103-2115.Elsevier BV. doi: 10.1016/j.ultrasmedbio.2013.04.023.

Hagandora, C.K., Gao, J., Wang, Y., & Almarza, A.J. (2013). Poly (Glycerol Sebacate): A Novel Scaffold Material for Temporomandibular Joint Disc Engineering. TISSUE ENGINEERING PART A, 19(5-6), 729-737.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2012.0304.

Jeffries, E.M., & Wang, Y. (2013). Incorporation of parallel electrospun fibers for improved topographical guidance in 3D nerve guides. BIOFABRICATION, 5(3), 035015.IOP Publishing. doi: 10.1088/1758-5082/5/3/035015.

Johnson, N.R., & Wang, Y. (2013). Controlled delivery of heparin-binding EGF-like growth factor yields fast and comprehensive wound healing. JOURNAL OF CONTROLLED RELEASE, 166(2), 124-129.Elsevier BV. doi: 10.1016/j.jconrel.2012.11.004.

Johnson, N.R., & Wang, Y. (2013). Controlled Delivery of Sonic Hedgehog Morphogen and Its Potential for Cardiac Repair. In Qin, G. (Ed.). PLOS ONE, 8(5), e63075.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0063075.

Lee, K.W., Johnson, N.R., Gao, J., & Wang, Y. (2013). Human progenitor cell recruitment via SDF-1α coacervate-laden PGS vascular grafts. BIOMATERIALS, 34(38), 9877-9885.Elsevier BV. doi: 10.1016/j.biomaterials.2013.08.082.

Li, H., Johnson, N.R., Usas, A., Lu, A., Poddar, M., Wang, Y., & Huard, J. (2013). Sustained Release of Bone Morphogenetic Protein 2 via Coacervate Improves the Osteogenic Potential of Muscle-Derived Stem Cells. STEM CELLS TRANSLATIONAL MEDICINE, 2(9), 667-677.Oxford University Press (OUP). doi: 10.5966/sctm.2013-0027.

Li, H., Johnson, N.R., Usas, A., Lu, A., Wang, Y., & Huard, J. (2013). Sustained Release of BMP2 via Coacervate Improves the Osteogenic Potential of Muscle-Derived Stem Cells. Stem Cells Translational Medicine, 2(9), 667-677.

Park, D., Larson, A.M., Klibanov, A.M., & Wang, Y. (2013). Antiviral and Antibacterial Polyurethanes of Various Modalities. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 169(4), 1134-1146.Springer Science and Business Media LLC. doi: 10.1007/s12010-012-9999-7.

Park, D., Shah, V., Rauck, B.M., Friberg, T.R., & Wang, Y. (2013). An Anti-angiogenic Reverse Thermal Gel as a Drug-Delivery System for Age-Related Wet Macular Degeneration. MACROMOLECULAR BIOSCIENCE, 13(4), 464-469.Wiley. doi: 10.1002/mabi.201200384.

Saparov, A., Chen, C.W., Beckman, S., Wang, Y., & Huard, J. (2013). The Role of Antioxidation and Immunomodulation in Postnatal Multipotent Stem Cell-Mediated Cardiac Repair. International Journal of Molecular Sciences, 14(8), 16258-16279.MDPI AG. doi: 10.3390/ijms140816258.

Saparoy, A., Chen, C.W., Beckman, S., Wang, Y., & Huard, J. (2013). The Role of Antioxidation and Immunomodulation in Stem Cell-Mediated Cardiac Repair. Int. J. Mol. Sci., 14(8), 16258-16279.

Yu, J., Takanari, K., Hong, Y., Lee, K.W., Amoroso, N.J., Wang, Y., Wagner, W.R., & Kim, K. (2013). Non-invasive characterization of polyurethane-based tissue constructs in a rat abdominal repair model using high frequency ultrasound elasticity imaging. BIOMATERIALS, 34(11), 2701-2709.Elsevier BV. doi: 10.1016/j.biomaterials.2013.01.036.

Chu, H., & Wang, Y. (2012). Therapeutic angiogenesis: controlled delivery of angiogenic factors. Ther Deliv, 3(6), 693-714.Future Science Ltd. doi: 10.4155/tde.12.50.

Chu, H., Gao, J., & Wang, Y. (2012). Design, synthesis, and biocompatibility of an arginine-based polyester. BIOTECHNOLOGY PROGRESS, 28(1), 257-264.Wiley. doi: 10.1002/btpr.728.

Jeffries, E.M., & Wang, Y. (2012). Biomimetic micropatterned multi-channel nerve guides by templated electrospinning. BIOTECHNOLOGY AND BIOENGINEERING, 109(6), 1571-1582.Wiley. doi: 10.1002/bit.24412.

Wu, W., Allen, R.A., & Wang, Y. (2012). Fast-degrading elastomer enables rapid remodeling of a cell-free synthetic graft into a neoartery. NATURE MEDICINE, 18(7), 1148-+.Springer Science and Business Media LLC. doi: 10.1038/nm.2821.

You, Z., & Wang, Y. (2012). A Versatile Synthetic Platform for a Wide Range of Functionalized Biomaterials. ADVANCED FUNCTIONAL MATERIALS, 22(13), 2812-2820.Wiley. doi: 10.1002/adfm.201102024.

You, Z., Bi, X., & Wang, Y. (2012). Fine Control of Polyester Properties via Epoxide ROP Using Monomers Carrying Diverse Functional Groups. MACROMOLECULAR BIOSCIENCE, 12(6), 822-829.Wiley. doi: 10.1002/mabi.201200035.

You, Z., Bi, X., Fan, X., & Wang, Y. (2012). A functional polymer designed for bone tissue engineering. ACTA BIOMATERIALIA, 8(2), 502-510.Elsevier BV. doi: 10.1016/j.actbio.2011.11.004.

You, Z., Bi, X., Jeffries, E.M., & Wang, Y. (2012). A biocompatible, metal-free catalyst and its application in microwave-assisted synthesis of functional polyesters. POLYMER CHEMISTRY, 3(2), 384-389.Royal Society of Chemistry (RSC). doi: 10.1039/c1py00400j.

Allen, R., & Wang, Y. (2011). Rapid Self-Assembly of Tubular Arterial Media Layer from Smooth Muscle Cells in Transient Fibrin Gel. J Tissue Sci Eng, 10(03).OMICS Publishing Group. doi: 10.4172/2157-7552.1000105e.

Chu, H., Gao, J., Chen, C.W., Huard, J., & Wang, Y. (2011). Injectable fibroblast growth factor-2 coacervate for persistent angiogenesis. In Langer, R. (Ed.). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(33), 13444-13449.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1110121108.

Chu, H., Johnson, N.R., Mason, N.S., & Wang, Y. (2011). A [polycation:heparin] complex releases growth factors with enhanced bioactivity. JOURNAL OF CONTROLLED RELEASE, 150(2), 157-163.Elsevier BV. doi: 10.1016/j.jconrel.2010.11.025.

Crapo, P.M., & Wang, Y. (2011). Hydrostatic pressure independently increases elastin and collagen co-expression in small-diameter engineered arterial constructs. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 96A(4), 673-681.Wiley. doi: 10.1002/jbm.a.33019.

Gumera, C., Rauck, B., & Wang, Y. (2011). Materials for central nervous system regeneration: bioactive cues. JOURNAL OF MATERIALS CHEMISTRY, 21(20), 7033-7051.Royal Society of Chemistry (RSC). doi: 10.1039/c0jm04335d.

Lee, K.W., & Wang, Y. (2011). Elastomeric PGS Scaffolds in Arterial Tissue Engineering. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (50).MyJove Corporation. doi: 10.3791/2691.

Park, D., Wu, W., & Wang, Y. (2011). A functionalizable reverse thermal gel based on a polyurethane/PEG block copolymer. BIOMATERIALS, 32(3), 777-786.Elsevier BV. doi: 10.1016/j.biomaterials.2010.09.044.

Wilson, M.E., Kota, N., Kim, Y., Wang, Y., Stolz, D.B., LeDuc, P.R., & Ozdoganlar, O.B. (2011). Fabrication of circular microfluidic channels by combining mechanical micromilling and soft lithography. LAB ON A CHIP, 11(8), 1550-1555.Royal Society of Chemistry (RSC). doi: 10.1039/c0lc00561d.

Wu, W., Allen, R., Gao, J., & Wang, Y. (2011). Artificial Niche Combining Elastomeric Substrate and Platelets Guides Vascular Differentiation of Bone Marrow Mononuclear Cells. TISSUE ENGINEERING PART A, 17(15-16), 1979-1992.Mary Ann Liebert Inc. doi: 10.1089/ten.tea.2010.0550.

Zern, B.J., Chu, H., Osunkoya, A.O., Gao, J., & Wang, Y. (2011). A Biocompatible Arginine-Based Polycation. ADVANCED FUNCTIONAL MATERIALS, 21(3), 434-440.Wiley. doi: 10.1002/adfm.201000969.

Crapo, P.M., & Wang, Y. (2010). Physiologic compliance in engineered small-diameter arterial constructs based on an elastomeric substrate. BIOMATERIALS, 31(7), 1626-1635.Elsevier BV. doi: 10.1016/j.biomaterials.2009.11.035.

Crapo, P.M., & Wang, Y. (2010). Small intestinal submucosa gel as a potential scaffolding material for cardiac tissue engineering. ACTA BIOMATERIALIA, 6(6), 2091-2096.Elsevier BV. doi: 10.1016/j.actbio.2009.10.048.

Marsano, A., Maidhof, R., Wan, L.Q., Wang, Y., Gao, J., Tandon, N., & Vunjak-Novakovic, G. (2010). Scaffold Stiffness Affects the Contractile Function of Three-Dimensional Engineered Cardiac Constructs. BIOTECHNOLOGY PROGRESS, 26(5), 1382-1390.Wiley. doi: 10.1002/btpr.435.

You, Z., Cao, H., Gao, J., Shin, P.H., Day, B.W., & Wang, Y. (2010). A functionalizable polyester with free hydroxyl groups and tunable physiochemical and biological properties. BIOMATERIALS, 31(12), 3129-3138.Elsevier BV. doi: 10.1016/j.biomaterials.2010.01.023.

Zern, B.J., Chu, H., & Wang, Y. (2010). Control Growth Factor Release Using a Self-Assembled [polycation:heparin] Complex. PLOS ONE, 5(6), e11017.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0011017.

Lee, E.J., Vunjak-Novakovic, G., Wang, Y., & Niklason, L.E. (2009). A Biocompatible Endothelial Cell Delivery System for In Vitro Tissue Engineering. CELL TRANSPLANTATION, 18(7), 731-743.SAGE Publications. doi: 10.3727/096368909X470919.

Sales, V.L., Kim, G.S., Gao, J., Rusk, E., Matthews, E., Wang, Y., Martin, D., Estrada, C., Walter, E.M.B., & Jr, M.J.E. (2009). Customizing Future Tissue Engineered Heart Valves Through Phenotypic Modulation of Progenitor Cells. CIRCULATION, 120(18), S597.

Secasanu, V.P., Giardina, C.K., & Wang, Y. (2009). A Novel Electrospinning Target to Improve the Yield of Uniaxially Aligned Fibers. BIOTECHNOLOGY PROGRESS, 25(4), 1169-1175.Wiley. doi: 10.1002/btpr.163.

Wang, Y., Goh, S.H., Bi, X., & Yang, K.L. (2009). Replication of DNA submicron patterns by combining nanoimprint lithography and contact printing. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 333(1), 188-194.Elsevier BV. doi: 10.1016/j.jcis.2009.02.010.

Crapo, P., Gao, J., & Wang, Y. (2008). Seamless Tubular Poly(glycerol sebacate) Scaffolds: High-yield Fabrication and Potential Applications. J. Biomed. Mat. Res. 86: 354-363, 2008. J. Biomed. Mat. Res., 86, 354-363.

Crapo, P.M., Gao, J., & Wang, Y. (2008). Seamless tubular poly(glycerol sebacate) scaffolds: High-yield fabrication and potential applications. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 86A(2), 354-363.Wiley. doi: 10.1002/jbm.a.31598.

Gao, J., Crapo, P., Nerern, R., & Wang, Y. (2008). Co-expression of elastin and collagen leads to highly compliant engineered blood vessels. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 85A(4), 1120-1128.Wiley. doi: 10.1002/jbm.a.32028.

Radisic, M., Marsano, A., Maidhof, R., Wang, Y., & Vunjak-Novakovic, G. (2008). Cardiac tissue engineering using perfusion bioreactor systems. NATURE PROTOCOLS, 3(4), 719-738.Springer Science and Business Media LLC. doi: 10.1038/nprot.2008.40.

Radisic, M., Park, H., Martens, T.P., Salazar-Lazaro, J.E., Geng, W., Wang, Y., Langer, R., Freed, L.E., & Vunjak-Novakovic, G. (2008). Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 86A(3), 713-724.Wiley. doi: 10.1002/jbm.a.31578.

Gao, J., Ensley, A.E., Nerem, R.M., & Wang, Y. (2007). Poly(glycerol sebacate) supports the proliferation and phenotypic protein expression of primary baboon vascular cells. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 83A(4), 1070-1075.Wiley. doi: 10.1002/jbm.a.31434.

Gumera, C.B., & Wang, Y. (2007). Modulating neuronal responses by controlled integration of acetylcholine-like functionalities in biomimetic polymers. ADVANCED MATERIALS, 19(24), 4404-+.Wiley. doi: 10.1002/adma.200701747.

Kim, Y.M., Gao, J., Zern, B., & Wang, Y.D. (2007). Biofunctional Materials for Nerve Regeneration. Materials Science Forum, 539-543(PART 1), 547-550.Trans Tech Publications Ltd. doi: 10.4028/0-87849-428-6.547.

Sales, V.L., Jr, E.G.C., Jr, J.J.A., Gao, J., Wang, Y., Sacks, M.S., & Mayer, J.E. (2007). Protein precoating of elastomeric tissue-engineering scaffolds increased cellularity, enhanced extracellular matrix protein production, and differentially regulated the phenotypes of circulating endothelial progenitor cells. CIRCULATION, 116(11), I55-I63.Ovid Technologies (Wolters Kluwer Health). doi: 10.1161/CIRCULATIONAHA.106.6806637.

Bettinger, C.J., Weinberg, E.J., Kulig, K.M., Vacanti, J.P., Wang, Y.D., Borenstein, J.T., & Langer, R. (2006). Three-dimensional microfluidic tissue-engineering scaffolds using a flexible biodegradable polymer. ADVANCED MATERIALS, 18(2), 165-+.Wiley. doi: 10.1002/adma.200500438.

Gao, J., Crapo, P.M., & Wang, Y. (2006). Macroporous elastomeric scaffolds with extensive micropores for soft tissue engineering. TISSUE ENGINEERING, 12(4), 917-925.Mary Ann Liebert Inc. doi: 10.1089/ten.2006.12.917.

Gao, J., Kim, Y.M., Coe, H., Zern, B., Sheppard, B., & Wang, Y. (2006). A neuroinductive biomaterial based on dopamine. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(45), 16681-16686.Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.0606237103.

Sales, V.L., Jr, E.G.C., Gottlieb, D., Jr, J.J.A., Gao, J., Wang, Y., Sacks, M.S., & Jr, M.J.E. (2006). Protein precoating of elastomeric tissue-engineering scaffolds: Extracellular matrix formation and phenotypic changes of circulating endothelial progenitor cells. CIRCULATION RESEARCH, 99(5), E35.

Wang, Y., Gao, J., Kim, Y., Coe, H., Zern, B., & Sheppard, B. (2006). A Neuro-inductive Biodegradable Material Based on Dopamine. Proc. Natl. Acad. Sci. U.S.A., 103, 16681-16686.

Fidkowski, C., Kaazempur-Mofrad, M.R., Borenstein, J., Vacanti, J.P., Langer, R., & Wang, Y.D. (2005). Endothelialized microvasculature based on a biodegradable elastomer. TISSUE ENGINEERING, 11(1-2), 302-309.Mary Ann Liebert Inc. doi: 10.1089/ten.2005.11.302.

Haaga, J.R., Exner, A.A., Wang, Y.D., Stowe, N.T., & Tarcha, P.J. (2005). Combined tumor therapy by using radiofrequency ablation and 5-FU-laden polymer implants: Evaluation in rats and rabbits. RADIOLOGY, 237(3), 911-918.Radiological Society of North America (RSNA). doi: 10.1148/radiol.2373041950.

Sundback, C.A., Shyu, J.Y., Wang, Y.D., Faquin, W.C., Langer, R.S., Vacanti, J.P., & Hadlock, T.A. (2005). Biocompatibility analysis of poly(glycerol sebacate) as a nerve guide material. BIOMATERIALS, 26(27), 5454-5464.Elsevier BV. doi: 10.1016/j.biomaterials.2005.02.004.

Ijima, H., Wang, Y.D., & Langer, R. (2004). Spheroid formation and expression of liver specific functions of primary rat hepatocytes co-cultured with bone marrow cells. BIOCHEMICAL ENGINEERING JOURNAL, 20(2-3), 223-228.Elsevier BV. doi: 10.1016/j.bej.2003.09.014.

Wang, Y.D., Kim, Y.M., & Langer, R. (2003). In vivo degradation characteristics of poly(glycerol sebacate). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 66A(1), 192-197.Wiley. doi: 10.1002/jbm.a.10534.

Wang, Y.D., Ameer, G.A., Sheppard, B.J., & Langer, R. (2002). A tough biodegradable elastomer. NATURE BIOTECHNOLOGY, 20(6), 602-606.Springer Science and Business Media LLC. doi: 10.1038/nbt0602-602.

Wang, Y.D., DuBois, J.L., Hedman, B., Hodgson, K.O., & Stack, T.D.P. (1998). Catalytic galactose oxidase models: Biomimetic Cu(II)-phenoxyl-radical reactivity. SCIENCE, 279(5350), 537-540.American Association for the Advancement of Science (AAAS). doi: 10.1126/science.279.5350.537.

Wang, Y.D., & Stack, T.D.P. (1996). Galactose oxidase model complexes: Catalytic reactivities. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 118(51), 13097-13098.American Chemical Society (ACS). doi: 10.1021/ja9621354.

Research interests

controlled release of proteins
drug delivery
Polymeric biomaterials
wound healing