MD, University of Pittsburgh School of Medicine, 2004 - 2011
PhD, University of Pittsburgh School of Medicine, 2006 - 2009
Sui, J., Johnson, A.R., Kapellos, T.S., Shiva, S., & Kliment, C.R. (2025). ANT1 Deficiency Impairs Macrophage Metabolism and Migration, Protecting Against Emphysema in COPD. Am J Respir Cell Mol Biol.American Thoracic Society. doi: 10.1165/rcmb.2024-0469OC.
Corcoran, T.E., Broerman, M.J., Kliment, C.R., & Lo, C. (2024). CFTR expression decreases with age in several airway cell types. Sci Rep, 14(1), 28832.Springer Nature. doi: 10.1038/s41598-024-80108-8.
Hu, Y., Hu, Q., Ansari, M., Riemondy, K., Pineda, R., Sembrat, J., Leme, A.S., Ngo, K., Morgenthaler, O., Ha, K., Gao, B., Janssen, W.J., Basil, M.C., Kliment, C.R., Morrisey, E., Lehmann, M., Evans, C.M., Schiller, H.B., & Königshoff, M. (2024). Airway-derived emphysema-specific alveolar type II cells exhibit impaired regenerative potential in COPD. Eur Respir J, 64(6), 2302071.European Respiratory Society (ERS). doi: 10.1183/13993003.02071-2023.
Sui, J., & Kliment, C. (2024). Reply to Kobayashi et al.: Adenine Nucleotide Translocases and Cellular Senescence in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol, 70(3), 226-227.American Thoracic Society. doi: 10.1165/rcmb.2023-0405LE.
Sui, J., Xiao, H., Mbaekwe, U., Ting, N.C., Murday, K., Hu, Q., Gregory, A.D., Kapellos, T.S., Yildirim, A.Ö., Königshoff, M., Zhang, Y., Sciurba, F., Das, J., & Kliment, C.R. (2024). Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD. JCI Insight, 9(21), e180239.American Society for Clinical Investigation. doi: 10.1172/jci.insight.180239.
Ware, S.A., Kliment, C.R., Giordano, L., Redding, K.M., Rumsey, W.L., Bates, S., Zhang, Y., Sciurba, F.C., Nouraie, S.M., & Kaufman, B.A. (2024). Cell-free DNA levels associate with COPD exacerbations and mortality. Respir Res, 25(1), 42.Springer Nature. doi: 10.1186/s12931-023-02658-1.
Risbano, M.G., Kliment, C.R., Dunlap, D.G., Koch, C., Campedelli, L., Yoney, K., Nouraie, S.M., Sciurba, F., & Morris, A. (2023). Invasive Cardiopulmonary Exercise Testing Identifies Distinct Physiologic Endotypes in Postacute Sequelae of SARS-CoV-2 Infection. CHEST Pulmonary, 1(3), 100010.Elsevier. doi: 10.1016/j.chpulm.2023.100010.
Sui, J., Boatz, J.C., Shi, J., Hu, Q., Li, X., Zhang, Y., Königshoff, M., & Kliment, C.R. (2023). Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis. Am J Respir Cell Mol Biol, 69(5), 556-569.American Thoracic Society. doi: 10.1165/rcmb.2022-0315OC.
Boatz, J.C., Sui, J., Hu, Q., Li, X., Zhang, Y., Königshoff, M., & Kliment, C.R. (2022). Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis. In bioRxiv. doi: 10.1101/2022.09.09.507271.
Florentin, J., O'Neil, S.P., Ohayon, L.L., Uddin, A., Vasamsetti, S.B., Arunkumar, A., Ghosh, S., Boatz, J.C., Sui, J., Kliment, C.R., Chan, S.Y., & Dutta, P. (2022). VEGF Receptor 1 Promotes Hypoxia-Induced Hematopoietic Progenitor Proliferation and Differentiation. Front Immunol, 13, 882484.Frontiers. doi: 10.3389/fimmu.2022.882484.
Ghosh-Choudhary, S., Carleton, N., Flynn, J.L., & Kliment, C.R. (2022). Strategies for Achieving Gender Equity and Work-Life Integration in Physician-Scientist Training. Acad Med, 97(4), 492-496.Wolters Kluwer. doi: 10.1097/ACM.0000000000004246.
Ghosh-Choudhary, S., Carleton, N., Nouraie, S.M., Kliment, C.R., & Steinman, R.A. (2022). Predoctoral MD-PhD grants as indicators of future NIH funding success. JCI Insight, 7(6), e155688.American Society for Clinical Investigation. doi: 10.1172/jci.insight.155688.
Kliment, C.R., & Gosens, R. (2022). Chymase-1: a "MAST"-er switch in COPD?. EUROPEAN RESPIRATORY JOURNAL, 60(6).
Kliment, C.R., Nguyen, J.M.K., Kaltreider, M.J., Lu, Y., Claypool, S.M., Radder, J.E., Sciurba, F.C., Zhang, Y., Gregory, A.D., Iglesias, P.A., Sidhaye, V.K., & Robinson, D.N. (2021). Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function. J Cell Sci, 134(4), jcs257162.The Company of Biologists. doi: 10.1242/jcs.257162.
Kliment, C.R., Barbash, I.J., Brenner, J.S., Chandra, D., Courtright, K., Gauthier, M.C., Robinson, K.M., Scheunemann, L.P., Shah, F.A., Christie, J.D., & Morris, A. (2020). COVID-19 and the Early-Career Physician-Scientist. Fostering Resilience beyond the Pandemic. ATS Sch, 2(1), 19-28.American Thoracic Society. doi: 10.34197/ats-scholar.2020-0104PS.
Suresh, K., Servinsky, L., Jiang, H., Bigham, Z., Zaldumbide, J., Huetsch, J.C., Kliment, C., Acoba, M.G., Kirsch, B.J., Claypool, S.M., Le, A., Damarla, M., & Shimoda, L.A. (2019). Regulation of mitochondrial fragmentation in microvascular endothelial cells isolated from the SU5416/hypoxia model of pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol, 317(5), L639-L652.American Physiological Society. doi: 10.1152/ajplung.00396.2018.
Gregory, A.D., Kliment, C.R., Metz, H.E., Kim, K.H., Kargl, J., Agostini, B.A., Crum, L.T., Oczypok, E.A., Oury, T.A., & Houghton, A.M. (2015). Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis. J Leukoc Biol, 98(2), 143-152.Oxford University Press (OUP). doi: 10.1189/jlb.3HI1014-493R.
Kliment, C.R., Araki, T., Doyle, T.J., Gao, W., Dupuis, J., Latourelle, J.C., Zazueta, O.E., Fernandez, I.E., Nishino, M., Okajima, Y., Ross, J.C., Estépar, R.S.J., Diaz, A.A., Lederer, D.J., Schwartz, D.A., Silverman, E.K., Rosas, I.O., Washko, G.R., O'Connor, G.T., Hatabu, H., & Hunninghake, G.M. (2015). A comparison of visual and quantitative methods to identify interstitial lung abnormalities. BMC Pulm Med, 15(1), 134.Springer Nature. doi: 10.1186/s12890-015-0124-x.
Zheng, M., Ramsay, A.J., Robichaux, M.B., Kliment, C., Crowe, C., Rapaka, R.R., Steele, C., McAllister, F., Shellito, J.E., Marrero, L., Schwarzenberger, P., Zhong, Q., & Kolls, J.K. (2015). Corrigendum. CD4+ T cell-independent DNA vaccination against opportunistic infections. J Clin Invest, 125(3), 1364.American Society for Clinical Investigation. doi: 10.1172/JCI81228.
Englert, J.M., Kliment, C.R., & Oury, T.D. (2014). Experimental Models of Asbestos-Related Diseases. In Pathology of Asbestos-Associated Diseases. (pp. 215-251).Springer Nature. doi: 10.1007/978-3-642-41193-9_10.
Englert, J.M., Kliment, C.R., Ramsgaard, L., Milutinovic, P.S., Crum, L., Tobolewski, J.M., & Oury, T.D. (2011). Paradoxical function for the receptor for advanced glycation end products in mouse models of pulmonary fibrosis. Int J Clin Exp Pathol, 4(3), 241-254.
Kliment, C.R., & Oury, T.D. (2011). Extracellular superoxide dismutase protects cardiovascular syndecan-1 from oxidative shedding. Free Radic Biol Med, 50(9), 1075-1080.Elsevier. doi: 10.1016/j.freeradbiomed.2011.02.014.
Kliment, C.R., Englert, J.M., Crum, L.P., & Oury, T.D. (2011). A novel method for accurate collagen and biochemical assessment of pulmonary tissue utilizing one animal. Int J Clin Exp Pathol, 4(4), 349-355.
Houghton, A.M., Rzymkiewicz, D.M., Ji, H., Gregory, A.D., Egea, E.E., Metz, H.E., Stolz, D.B., Land, S.R., Marconcini, L.A., Kliment, C.R., Jenkins, K.M., Beaulieu, K.A., Mouded, M., Frank, S.J., Wong, K.K., & Shapiro, S.D. (2010). Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med, 16(2), 219-223.Springer Nature. doi: 10.1038/nm.2084.
Kliment, C.R., & Oury, T.D. (2010). Oxidative stress, extracellular matrix targets, and idiopathic pulmonary fibrosis. Free Radic Biol Med, 49(5), 707-717.Elsevier. doi: 10.1016/j.freeradbiomed.2010.04.036.
Kliment, C.R., Clemens, K., & Oury, T.D. (2009). North american erionite-associated mesothelioma with pleural plaques and pulmonary fibrosis: a case report. Int J Clin Exp Pathol, 2(4), 407-410.
Kliment, C.R., Englert, J.M., Gochuico, B.R., Yu, G., Kaminski, N., Rosas, I., & Oury, T.D. (2009). Oxidative stress alters syndecan-1 distribution in lungs with pulmonary fibrosis. J Biol Chem, 284(6), 3537-3545.Elsevier. doi: 10.1074/jbc.M807001200.
Kliment, C.R., Suliman, H.B., Tobolewski, J.M., Reynolds, C.M., Day, B.J., Zhu, X., McTiernan, C.F., McGaffin, K.R., Piantadosi, C.A., & Oury, T.D. (2009). Extracellular superoxide dismutase regulates cardiac function and fibrosis. J Mol Cell Cardiol, 47(5), 730-742.Elsevier. doi: 10.1016/j.yjmcc.2009.08.010.
Carraway, M.S., Suliman, H.B., Kliment, C., Welty-Wolf, K.E., Oury, T.D., & Piantadosi, C.A. (2008). Mitochondrial biogenesis in the pulmonary vasculature during inhalational lung injury and fibrosis. Antioxid Redox Signal, 10(2), 269-275.Mary Ann Liebert. doi: 10.1089/ars.2007.1910.
Kliment, C.R., Tobolewski, J.M., Manni, M.L., Tan, R.J., Enghild, J., & Oury, T.D. (2008). Extracellular superoxide dismutase protects against matrix degradation of heparan sulfate in the lung. Antioxid Redox Signal, 10(2), 261-268.Mary Ann Liebert. doi: 10.1089/ars.2007.1906.
Myllärniemi, M., Lindholm, P., Ryynänen, M.J., Kliment, C.R., Salmenkivi, K., Keski-Oja, J., Kinnula, V.L., Oury, T.D., & Koli, K. (2008). Gremlin-mediated decrease in bone morphogenetic protein signaling promotes pulmonary fibrosis. Am J Respir Crit Care Med, 177(3), 321-329.American Thoracic Society. doi: 10.1164/rccm.200706-945OC.
Zheng, M., Ramsay, A.J., Robichaux, M.B., Kliment, C., Crowe, C., Rapaka, R.R., Steele, C., McAllister, F., Shellito, J.E., Marrero, L., Schwarzenberger, P., Zhong, Q., & Kolls, J.K. (2005). CD4+ T cell-independent DNA vaccination against opportunistic infections. J Clin Invest, 115(12), 3536-3544.American Society for Clinical Investigation. doi: 10.1172/JCI26306.