(2019 - 2020) Alzheimer's Disease Research Center Seed Grant.
(2017 - 2020) Alzheimer’s Association Research Fellowship ($175K).
(2016) Alzheimer’s Imaging Consortium Fellowship.
(2016 - 2017) NINDS T32 Training Fellowship, Neurobiology of Neurological Disease.
(2012) International Society of MR in Medicine - Summa Cum Laude Award.
(2007 - 2010) National Science Foundation Graduate Research Fellowship.
PhD, Carnegie Mellon University, 2005 - 2011
Schweitzer, N., Li, J., Thurston, R.C., Lopresti, B., Klunk, W.E., Snitz, B., Tudorascu, D., Cohen, A., Kamboh, M.I., Halligan-Eddy, E., Iordanova, B., Villemagne, V.L., Aizenstein, H., & Wu, M. (2024). Sex-dependent alterations in hippocampal connectivity are linked to cerebrovascular and amyloid pathologies in normal aging. Alzheimers Dement, 20(2), 914-924.Wiley. doi: 10.1002/alz.13503.
Wu, M., Schweitzer, N., Iordanova, B.E., Halligan-Eddy, E., Tudorascu, D.L., Mathis, C.A., Lopresti, B.J., Kamboh, M.I., Cohen, A.D., Snitz, B.E., Klunk, W.E., & Aizenstein, H.J. (2023). In Pre-Clinical AD Small Vessel Disease is Associated With Altered Hippocampal Connectivity and Atrophy. Am J Geriatr Psychiatry, 31(2), 112-123.Elsevier. doi: 10.1016/j.jagp.2022.09.011.
Oghifobibi, O.A., Toader, A.E., Nicholas, M.A., Nelson, B.P., Alindogan, N.G., Wolf, M.S., Kline, A.E., Nouraie, S.M., Bondi, C.O., Iordanova, B., Clark, R.S., Bayır, H., Loughran, P.A., Watkins, S.C., St Croix, C.M., Kochanek, P.M., Vazquez, A.L., & Manole, M.D. (2022). Resuscitation with epinephrine worsens cerebral capillary no-reflow after experimental pediatric cardiac arrest: An in vivo multiphoton microscopy evaluation. J Cereb Blood Flow Metab, 42(12), 2255-2269.SAGE Publications. doi: 10.1177/0271678X221113022.
Fitz, N.F., Nam, K.N., Wolfe, C.M., Letronne, F., Playso, B.E., Iordanova, B.E., Kozai, T.D.Y., Biedrzycki, R.J., Kagan, V.E., Tyurina, Y.Y., Han, X., Lefterov, I., & Koldamova, R. (2021). Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer's disease. Nat Commun, 12(1), 3416.Springer Nature. doi: 10.1038/s41467-021-23762-0.
Poplawsky, A.J., Iordanova, B., Vazquez, A.L., Kim, S.G., & Fukuda, M. (2021). Postsynaptic activity of inhibitory neurons evokes hemodynamic fMRI responses. Neuroimage, 225, 117457.Elsevier. doi: 10.1016/j.neuroimage.2020.117457.
Fitz, N., Nam, K., Wolfe, C., Letronne, F., Playso, B., Iordanova, B., Kozai, T., Biedrzycki, R., Kagan, V., Tyurina, Y., Han, X., Lefterov, I., & Koldamova, R. (2020). Phospholipid Composition of APOE Lipoproteins Affects Microglia Activation in an Isoform-specific Manner. Research Square Platform. doi: 10.21203/rs.3.rs-83085/v1.
Fukuda, M., Poplawsky, A.J., Iordanova, B., Vazquez, A.L., & Kim, S.G. (2019). Coupling of neuronal activity to blood flow in dendrodendritic synapses is mediated by postsynaptic gabaergic cells in olfactory bulb. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 39, 239-240.
Iordanova, B., Vazquez, A., Kozai, T.D., Fukuda, M., & Kim, S.G. (2018). Optogenetic investigation of the variable neurovascular coupling along the interhemispheric circuits. J Cereb Blood Flow Metab, 38(4), 627-640.SAGE Publications. doi: 10.1177/0271678X18755225.
Jin, T., Iordanova, B., Hitchens, T.K., Modo, M., Wang, P., Mehrens, H., & Kim, S.G. (2018). Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors. Magn Reson Med, 80(2), 488-495.Wiley. doi: 10.1002/mrm.27183.
Jin, T., Iordanova, B., Hitchens, T.K., Modo, M., Wang, P., Mehrens, H., & Kim, S.G. (2018). Chemical exchange-sensitive spin-lock (CESL) MRI of glucose and analogs in brain tumors. Magn Reson Med, 80(2), 488-495.Wiley. doi: 10.1002/mrm.27183.
Iordanova, B., Li, L., Clark, R.S.B., & Manole, M.D. (2017). Alterations in Cerebral Blood Flow after Resuscitation from Cardiac Arrest. Front Pediatr, 5, 174.Frontiers. doi: 10.3389/fped.2017.00174.
Iordanova, B., Murphy, M.C., Klunk, W.E., & Vazquez, A.L. (2016). P4‐093: In Vivo NADH Fluorescence Imaging of Double Transgenic Alzheimer's Disease Mice Reveals Chronic Tissue Hypoxia. Alzheimer's & Dementia, 12(7S_Part_21), p1047-p1048.Wiley. doi: 10.1016/j.jalz.2016.06.2182.
Iordanova, B., Vazquez, A.L., Poplawsky, A.J., Fukuda, M., & Kim, S.G. (2015). Neural and hemodynamic responses to optogenetic and sensory stimulation in the rat somatosensory cortex. J Cereb Blood Flow Metab, 35(6), 922-932.SAGE Publications. doi: 10.1038/jcbfm.2015.10.
Iordanova, B., Goins, W.F., Clawson, D.S., Hitchens, T.K., & Ahrens, E.T. (2013). Quantification of HSV-1-mediated expression of the ferritin MRI reporter in the mouse brain. Gene Ther, 20(6), 589-596.Springer Nature. doi: 10.1038/gt.2012.70.
Iordanova, B., Hitchens, T.K., Robison, C.S., & Ahrens, E.T. (2013). Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium. In Gelovani, J.G. (Ed.). PLoS One, 8(8), e72720.Public Library of Science (PLoS). doi: 10.1371/journal.pone.0072720.
Iordanova, B., & Ahrens, E.T. (2012). In vivo magnetic resonance imaging of ferritin-based reporter visualizes native neuroblast migration. Neuroimage, 59(2), 1004-1012.Elsevier. doi: 10.1016/j.neuroimage.2011.08.068.
Iordanova, B., & Ahrens, E.T. (2012). MRI Reporter Genes for Cancer Research. In Molecular Imaging Probes for Cancer Research. (pp. 715-731).World Scientific Publishing. doi: 10.1142/9789814293686_0024.
Iordanova, B., Robison, C.S., & Ahrens, E.T. (2010). Design and characterization of a chimeric ferritin with enhanced iron loading and transverse NMR relaxation rate. J Biol Inorg Chem, 15(6), 957-965.Springer Nature. doi: 10.1007/s00775-010-0657-7.
Iordanova, B., Robison, C.S., Goins, W.F., & Ahrens, E.T. (2010). Single chain ferritin chimera as an improved MRI gene reporter. Prilozi, 31(2), 151-155.
Iordanova, B., Rosenbaum, D., Norman, D., Weiner, M., & Studholme, C. (2006). MR imaging anatomy in neurodegeneration: a robust volumetric parcellation method of the frontal lobe gyri with quantitative validation in patients with dementia. AJNR Am J Neuroradiol, 27(8), 1747-1754.
Rousseau, F., Glenn, O.A., Iordanova, B., Rodriguez-Carranza, C., Vigneron, D.B., Barkovich, J.A., & Studholme, C. (2006). Registration-based approach for reconstruction of high-resolution in utero fetal MR brain images. Acad Radiol, 13(9), 1072-1081.Elsevier. doi: 10.1016/j.acra.2006.05.003.
Studholme, C., Drapaca, C., Iordanova, B., & Cardenas, V. (2006). Deformation-based mapping of volume change from serial brain MRI in the presence of local tissue contrast change. IEEE Trans Med Imaging, 25(5), 626-639.Institute of Electrical and Electronics Engineers (IEEE). doi: 10.1109/TMI.2006.872745.
Rousseau, F., Glenn, O., Iordanova, B., Rodriguez-Carranza, C., Vigneron, D., Barkovich, J., & Studholme, C. (2005). A novel approach to high resolution fetal brain MR imaging. Med Image Comput Comput Assist Interv, 8(Pt 1), 548-555.Springer Nature. doi: 10.1007/11566465_68.
Schweitzer, N., Cover, C., Wu, M., Aizenstein, H., Vazquez, A., & Iordanova, B. (2022). Sex differences in vascular reactivity of APP/PS1 mouse model of Alzheimer's disease. In JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 42(1_SUPPL), (p. 25).
Iordanova, B., Fukuda, M., Klunk, W., & Vazquez, A.L. (2019). Vascular and metabolic dysfunctions in APP/PS1 mouse model of Alzheimer's disease. In JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 39, (pp. 44-45).
Iordanova, B., Klunk, W.E., & Vazquez, A.L. (2018). P1‐441: HYPERCAPNIA EXPOSES DEFICIENCIES IN CEREBROVASCULAR RESPONSE AND TISSUE OXYGENATION IN TRANSGENIC AD MICE. In Alzheimer's & Dementia, 14(7S_Part_8), (p. p480).Wiley. doi: 10.1016/j.jalz.2018.06.450.
Koldamova, R., Lefterov, I., Fitz, N.F., Nam, K.N., Wolfe, C.M., Iordanova, B.Koldamova, R., Lefterov, I. (2018). P4‐051: EFFECT OF APOE ISOFORM ON MICROGLIAL RESPONSE TO AMYLOID‐BETA. In Alzheimer's & Dementia, 14(7S_Part_27), (p. p1453).Wiley. doi: 10.1016/j.jalz.2018.06.2454.
Iordanova, B., Murphy, M.C., Klunk, W.E., & Vazquez, A.L. (2016). IC‐P‐030: In Vivo Nadh Fluorescence Imaging of Double Transgenic Ad Mice Reveals Chronic Tissue Hypoxia. In Alzheimer's & Dementia, 12(7S_Part_1), (pp. p30-p31).Wiley. doi: 10.1016/j.jalz.2016.06.040.
Rodriguez-Carranza, C.E., Rousseau, F., Iordanova, B., Glenn, O., Vigneron, D., Barkovich, J., & Studholme, C. (2006). An ISO-surface folding analysis method applied to premature neonatal brain development. In Reinhardt, J.M., & Pluim, J.P.W. (Eds.). In Proceedings of SPIE--the International Society for Optical Engineering, 6144, (p. 61441k-61441k-11).SPIE, the international society for optics and photonics. doi: 10.1117/12.652516.
Rousseau, F., Glenn, O., Iordanova, B., Rodriguez-Carranza, C., Vigneron, D., Barkovich, J., & Studholme, C. (2005). A novel approach to high resolution fetal brain MR imaging. In Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 8(Pt 1), (pp. 548-555).