The Issues

Dendritic Cells

The human immunodeficiency virus (HIV) infects and hides within lyphocytes, eventually destroying crucial cell types in the body's immune system. This virus has become a pandemic and the United Nations estimates that over 0.6% of the world's population is infected. With no cure currently available, infected individuals eventually succumb the opportunistic infections and malignancies associated with the AIDS (acquired immune deficiency syndrome).

Anti-viral therapeutics have extended the life expectancy of infected individuals from 10-11 years up to 20 or 30 years by some estimates. These treatments rely on a cocktail of pills and injections that must be taken at set times and with specific dietary requirements, often leading to poor patient compliance. At the Little Lab, we are working to reprocess these antiviral medications into extended release formulations which minimize dose related side effects and improve patient compliance.

For more detailed information on HIV and its treatment, please visit the following websites: