The Issues

Islet Cells

Cancer is the proliferation of genetically abnormal cells within the body. The 7.6 million lives that cancer claims annually are a strong indicator that significant advances are needed in the treatment of this disease. Traditional treatments for cancer include radiation and chemotherapy which eliminate tumor cells with an ionizing beam and lethal chemicals, respectively.


Recently therapeutics have progressed from these crude approaches to more focused strategies based on an ever-expanding pool of knowledge about cancer biology and immunology. These targeted treatments range from simple targeted therapeutics where a chemotherapeutic drug is coupled to a tumor specific antibody to more encompassing strategies where the patient's own immune system is mobilized to respond to target the cancer. In the Little Lab, we are developing a series off-the-shelf immunotherapeutics that work synergistically, engaging multiple arms of the immune system to effectively rout cancer on a cellular level.

For more detailed information on cancer and its treatment, please visit either of the following websites: