Pitt | Swanson Engineering
Biomechanics of the Lamina Cribrosa in Glaucoma
  • Biomechanics of the Lamina Cribrosa in Glaucoma

    The lamina cribrosa is a trabeculated soft tissue in the optic nerve head that is responsible for protecting the axons of the retinal ganglion cells as they pass from the inside of the eye to the brain. Axonal damage of retinal ganglion cells occurs in primary open angle glaucoma as this structure is grossly remodeled during the disease process. Our laboratory is assessing the biomechanical environment of this important ocular tissue in both normal and diseased human and animal tissue.  


Two photon projection image of the lamina cribrosa during increasing IOP

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