Faculty Group Projects

The Center for Medical Innovation has been supporting many different development projects with the potential to address major clinical shortcomings in medicine.  Below are a few of our highlights:


An Assay for Matrix Metalloproteinases

Researchers at the University of Pittsburgh have developed an assay that can in an ultrasensitive manner detect hematuria not associated with bladder cancer in patients. Clinical workup of asymptomatic hematuria continues to be challenging due to the heterogeneity of the underlying conditions. While . . .

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I-Hits: A New Approach to Stroke Rehabilitation Across the world, stroke-induced loss of hand movement and function is a major financial burden on healthcare systems, due to long term treatments with inconsistent outcomes.  Associated costs are projected to top 241 billion USD by 2030.  The human c . . .

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Development of a Fat Extraction/Transfer Cannula for Greater Fat Particle Size Control

The University of Pittsburgh CMI program has funded and collaborated on the development of the PrecisionGraftTM lipotransfer cannula.  A team of engineering faculty and physicians designed, constructed, and tested a prototype device which can be tuned to mechanically extract smaller fat particles fr . . .

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-- A Procedure to Convert Sickle Cell Red Blood Cells (RBCs) to Normal RBCs

Dr. Marina Kameneva of the McGowan Institute for Regenerative Medicine and her team have partnered with CMI to begin development of a real-world procedure to convert Sickle Cell Disease red blood cells (RBC HbS) into normal, healthy cells (RBC Hb). Sickle Cell Disease is caused by mutant hemogl . . .

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-- A Tablet-Based, Single Image Diagnostic Tool for Quantitative Analysis of ACL Injuries

Engineering Faculty at the University of Pittsburgh and Physicians from the UPMC health system have developed a new algorithm and iPad-compatible application to enable physicians to more effectively diagnose damage to the Anterior Cruciate Ligament (ACL) in the knee.  When completed, it could facili . . .

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