Pitt | Swanson Engineering
Shroff, Sanjeev Govinddas
Bioengineering Department
Shroff, Sanjeev Govinddas
Distinguished Professor and Gerald McGinnis Chair
Faculty
Professor
Office: CNBIO 308
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Research Interests: Mechano-energetic function of the heart, underlying cellular processes.

Ph.D. in Doctor of Philosophy (Bioengineering), University of Pennsylvania, 1976-1981

M.S. in Master of Engineering (Electrical), McMaster University, 1974-1976

B.S. in Bachelor of Technology (Electronics), Indian Institute of Technology, 1969-1974

(2011) 2011 Chancellor's Distinguished Teaching Award, University of Pittsburgh, Pittsburgh, PA.

(2010) 2010 Outstanding Educator Award, Swanson School of Enginering, University of Pittsburgh, Pittsburgh, PA.

(2007) Awards for Excellence (University/Post-Secondary Educator), Carnegie Science Center, Pittsburgh, PA.

(2007) Fellow (elected), Biomedical Engineering Society.

(2007) Best Mentor Award, EXCEL Summer Research Internship Program, School of Engineering, University of Pittsburgh, Pittsburgh, PA.

(2003) Mentor of the Year Award, School of Engineering, University of Pittsburgh, Pittsburgh, PA.

(2003) Robert O. Agbede Award for Diversity, School of Engineering, University of Pittsburgh, Pittsburgh, PA.

(2002) 2003 Board of Visitors Outstanding Faculty Award, School of Engineering, University of Pittsburgh, Pittsburgh, PA.

(2001) Faculty Honor Roll, Outstanding Professor, Engineering Student Body, University of Pittsburgh, Pittsburgh, PA.

(1999) Fellow (elected), American Institute for Medical and Biological Engineering.

(1988) Fellow (elected), Cardiovascular Section, American Physiological Society.

(1987) Established Investigator, American Heart Association.

(1974) Certificate of Merit, Indian Institute of Technology, Kanpur, India.

(1974) Benefactor Merit Scholarship, McMaster University, Hamilton, Ontario, Canada.

(1969) Government of India National Merit Certificate.

Shroff, S.G., Janczewski, A.M., Tobita, K., Liu, L.J., Tinney, J.P., Nonemaker, J.M., Augustine, S., Stolz, D.B., and Keller, B.B., "Contractile force regulation in early embryonic engineered cardiac tissue constructs and matching native chick ventricular myocardium," J. Appl. Physiol, Manuscript submitted for publication.

Shroff, S.G., Kim, H.K., Zenker, S., Johnson, L., and Pinsky, M.R., "Differential effects of left ventricular pacing sitres on regional contraction patterns," Am. J. Physiol, Manuscript submitted for publication.

Shroff, S.G., Schwartzman, D.S., Wong, T.C., Piehler, K., Meier, C.G., Testa, S.M., Klock, A.M., Aneizi, A.A., Shakesprere, J., Kellman, P., Mulukutla, S.R., Simon, M.A., and Schelbert, E.B., In press, "Association between fibrosis in noninfarcted myocardium quantified by cardiovascular magnetic resonance and short term mortality," Circulation.

Ahmad, F., Sharma, R.K., Wang, D.W., Smith, S.H., Banerjee, S.K., Huang, X.N., Lage, M.L., Gabris, B.E., Saba, S., Shroff, S.G., and Salama, G., "A gene targeted murine model of the human cardiac troponin T (TNNT2) R141W mutation develops dilated cardiomyopathy with calcium desensitization," Ciculation, Manuscript submitted for publication.

Hunsberger, A., Wang, Y., Ferreira, A., Vandenberg, S., Antaki, J., and Shroff, S.G., "Interaction between Thoratec pneumatic VAD and native cardiovascular system: I. Model development," ASIAO J., Manuscript submitted for publication.

Hunsberger, A., Wang, Y., Ferreira, A., Vandenberg, S., Antaki, J., and Shroff, S.G., "Interaction between Thoratec pneumatic VAD and native cardiovascular: II. Analysis of synchrony," ASIAO J., Manuscript submitted for publication.

Janczewski, A.M., Tobita, K., Liu, L.J., Tinney, J.P., Nonemake, J.M., Augustine, S., Stolz, D.B., Keller, B.B., and Shroff, S.G., "Contractile force regulation in early embryonic engineered cardiac tissue constructs and matching native chick ventricular myocardium," J. Appl. Physiol., Manuscript submitted for publication.

Kirk, J.A., Saccomani, M.P., and Shroff, S.G., 2013, "A priori identifiability analysis of cardiovascular models," Cardiovasc Eng Technol.

Parikh, A., PAtel, D.R., McTiernan, C.F., Xiang, W., Haney, J., Yang, L., Lin, B., Kaplan, A.D., Bett, G., Rasmusson, R.L., Shroff, S.G., Schwartzman, D.S., and Salama, G., 2013, "Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy, and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts," Circ Res, vol.113, pp. 313-321.

Wong, T.C., Piehler, K., Kang, I.A., Kadakkal, A., Kellman, P., Schwartzman, D.S., Mulukutla, S.R., Simon, M.A., Shroff, S.G., Kuller, L.H., and Schelbert, E.B., 2013, "Myocardial extracellular volume fraction quantified by cardiovascular magnetic resonance is increased in diabetes and associated with mortality and incident heart failure admission," Eur Heart J.

Shroff, S.G., Johnson, L., Lamia, B., Kim, H.K., Tanabe, M., Gorcsan, J., Schwartzman, D., and Pinsky, M.R., 2012, "Physiological relevance of quantifying segmental contraction synchrony," PACE, vol.35, pp. 174-187.

Shroff, S.G., and Conrad, K.P., 2011, "Effects of relaxin on arterial dilation, remodeling, and mechanical properties," Curr Hypertens Rep, vol.13, pp. 409-420.

Shroff, S.G., Debrah, D.O., Debrah, J.E., Haney, J.L., McGuane, J.T., Sacks, M.S., and Conrad, K.P., 2011, "Relaxin regulates vascular wall remodeling and passive mechanical properties in mice," J. Appl. Physiol, vol.111, pp. 260-271.

Shroff, S.G., Samant, S.A., Courson, D.S., Sudaresan, N.R., Pillai, V.B., Rock, R.S., and Gupta, M.P., 2011, "HDAC3-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity," J. Biol. Chem, vol.286, pp. 5567-5577.

Shroff, S.G., Schelbert, E., Testa, S.M., Meier, C.G., Ceyrolles, W.J., Levenson, J.E., Blair, A.J., Kellman, P., Jones, B.L., Ludwig, D.R., Schwartman, D., and Wong, T.C., 2011, "Myocardial extracellular volume fraction measurement by contrast CMR in humans: Slow infusion versus bolus," J Cardiovasc Magn Reson, vol.13, p. 16.

Shroff, S.G., and He, Y., 2010, "Cyclic stretch downregulates arterial connexin43 protein expression : An ex vivo study," Biomech. Model. Mechanobiol, vol.9, pp. 203-211.

Shroff, S.G., Bank, A.J., Kaufman, C.L., Burns, K.V., Parah, J.S., Johnson, L., Kelly, A.S., and Kaiser, D.R., 2010, "Intramural dyssynchrony and response to cardiac resynchronization therapy in patients with and without previous right ventricular pacing," Eur J Heart Fail, vol.12, pp. 1317-1324.

Shroff, S.G., Clause, K.C., Tinney, J.P., Liu, J.L., Gharaibeh, B., Huard, J., Kirk, J.A., Fujimoto, K.L., Wagner, W.R., Ralphe, J.C., Keller, B.B., and Tobita, K., 2010, "A three-dimensional gel bioreactor for assessment of cardiomyocyte induction in skeletal muscle derived stem cells," Tissue Eng. Part C, vol.16, pp. 375-385.

Shroff, S.G., Schwartzman, D., Johnson, L., Tanaka, H., Oat, T., Pinsky, M., and Gorcsan, J., 2010, "Dynamic and site-specific impact of ventricular pacing on left ventricular ejection fraction," Heart Rhythm, vol.7, pp. 813-819.

Shroff, S.G., Hibbard, J.U., and Lindheimer, M.D., 2009, "Cardiovascular alterations in normal and preeclamptic pregnancy," in Chesley's Hypertensive Diseases in Pregnancy (3rd ed.), F.G. Cunningham, M.D. Lindheimer, and J.M. Roberst, eds., Academic Press, pp. 249-267, New York.

Shroff, S.G., Johnson, L., Simon, M., and Pinsky, M.R., 2009, "Insights into the effects of contraction dyssynchrony on global left ventricular mechano-energetic function," PACE, vol.2, pp. 224-233.

Shroff, S.G., Kirk, J.A., MacGowan, G.A., Evans, C., Smith, S.H., Warren, C.M., Mamidi, R., Chnadra, M., Stewart, A.F., and Solaro, R.J., 2009, ". Left ventricular and myocardial function in mice expressing constitutively pseudo-phosphorylated cardiac troponin I," Circ. Res, vol.105, pp. 1232-1239.

Shroff, S.G., Lyczkowski, R.W., Alevriadou, R., Horner, M., and Panchal, C., 2009, "Application of multiphase fluid dynamics to analyze monocyte adhesion," Annal. Biomed. Eng, vol.37, pp. 1516-1533.

Shroff, S.G., McGuane, J.T., Debrah, J.E., Debrah, D.O., Rubin, J.P., Segal, M., and Conrad, K.P., 2009, "Role of relaxin in maternal systemic and renal vascular adaptations during gestation," Ann NY Acad. Sci, vol.1160, pp. 304-312.

Shroff, S.G., Naghshin, J., Janczewski, A.M., Smith, S.H., Romano, L.C., Mathier, M.A., McGaffin, K., and O'Donnell, C.P., 2009, "Chronic intermittent hypoxia increases cardiac contractility in C57BL/6J mice," J. Appl. Physiol, vol.107, pp. 787-793.

Shroff, S.G., Simon, M.A., Deible, C., Mathier, M.A., Lacomis, J., Goitein, O., and Pinsky, M.R., 2009, "Phenotyping the right ventricle in patients with pulmonary hypertension," Clin. Trans. Sci, vol.2, pp. 294-299.

Shroff, S.G., Simon, M.A., Rajagopalan, N., Pinsky, M.R., Lopez-Candales, A., and Mathier, M.A., 2009, "Tissue Doppler imaging of right ventricular decompensation in pulmonary hypertension," Conges. Heart Failure, vol.15, pp. 271-276.

Shroff, S.G., Ahmad, F., Banerjee, S.K., Lage, M.L., Huang, X.N., Smith, S.H., Saba, S., Rager, J., Conner, D.A., Janczewski, A.M., Tobita, K., Tinney, J.P., Moskowitz, I.P., Perez-Atayde, A.R., Keller, B.B., Mathier, M.A., Seidman, C.E., and Seidman, J.G., 2008, "The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy," PLoS ONE (doi:10.1371/journal.pone.0002642), vol.3, no.7, e2642 (1-11).

Shroff, S.G., Gupta, M.P., Samant, S., and Smith, S.H., 2008, "HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating the myofilament contractile activity," J. Biol. Chem, vol.283, no.15, pp. 10135-10146.

Shroff, S.G., Jeyabalan, A., Novak, J., and Conrad, K.P., 2007, "The vascular actions of relaxin," Adv. Exp. Med. Biol, vol.612, pp. 65-87.

Shroff, S.G., Johnson, L., Kim, H.K., Tanabe, M., Gorcsan, J., Schwartzman, D., and Pinsky, M.R., 2007, "Differential effects of left ventricular pacing sites in an acute canine model of contraction dyssynchrony," Am. J. Physiol. Heart Circ. Physiol, vol.293, H3046-H3055.

Shroff, S.G., Debrah, D.O., Novak, J., Matthews, J.E., Ramirez, R.J., and Conrad, K.P., 2006, "Relaxin is essential for systemic vasodilation and increased global arterial compliance during early pregnancy in conscious rats," Endocrinology, vol.147, pp. 5126-5131.

Shroff, S.G., MacGowan, G.A., Kirk, J., and Evans, C., 2006, "Pressure-calcium relationships in perfused mouse hearts," Am. J. Physiol. Heart Circ. Physiol, vol.290, H2614-H2624.

Shroff, S.G., Novak, J., Parry, L.J., Matthews, J., Kerchner, L.J., Indovina, K., Hanley-Yanez, K., Doty, K.D., Debrah, D.O., and Conrad barnyak, N.K., 2006, "Evidence for local relaxin ligand-receptor expression and function in arteries," FASEB J, vol.20, pp. 2352-2362.

Shroff, S.G., Tobita, K., Liu, L.J., Nonemaker, J.M., Janczewski, A.M., Tinney, J.P., Augustine, S., Stolz, D., and Keller, B.B., 2006, "Engineered early embryonic cardiac tissue retains proliferative and contractile properties of developing cardiac myocardium," Am. J. Physiol. Heart Circ. Physiol, vol.291, H1829-H1837.

Shroff, S.G., Campbell, K.B., Wu, Y., Simpson, A.M., Kirkpatrick, R.D., Granzier, H.L., and Slinker, B.K., 2005, "Dynamic myocardial contractile parameters from left ventricular pressure/volume measurements," Am. J. Physiol. Heart Circ. Physiol, vol.289, H114-H130.

Shroff, S.G., Debrah, D.O., Conrad, K.P., and Danielson, L.A., 2005, "Effects of relaxin on systemic arterial hemodynamics and mechanical properties in conscious rats: Sex dependency and dose response," J. Appl. Physiol, vol.1041, pp. 155-162.

Shroff, S.G., Debrah, D.O., Conrad, K.P., Jeyabalan, A., and Danielson, L.A., 2005, "Relaxin increases cardiac output and reduces systemic arterial load in hypertensive rats," Hypertension, vol.46, pp. 745-750.

Shroff, S.G., Debrah, D.O., Conrad, K.P., Novak, J., and Danielson, L.A., 2005, "Recombinant human relaxin (rhRLX) modifies systemic arterial properties in conscious rats irrespective of gender, but in a biphasic fashion," Ann. N. Y. Acad. Sci, vol.98, pp. 1013-1020.

Shroff, S.G., Hibbard, J.U., Korcarz, C.E., Giradet-Nendaz, G., Lindheimer, M.D., and Lang, R.M., 2005, "The arterial system in pre-eclampsia and chronic hypertension with superimposed pre-eclampsia," British J. Obstet. Gynecol, vol.112, pp. 897-903.

Shroff, S.G., MacGowan, G.A., Rager, J., and Mathier, M., 2005, "In-vivo ┬┐-adrenergic responses and troponin I phosphorylation: Anesthesia interactions," J. Appl. Physiol, vol.98, pp. 1163-1170.

Shroff, S.G., Conrad, K.P., Debrah, D.O., Novak, J., and Danielson, L.A., 2004, "Relaxin modifies systemic arterial resistance and compliance in conscious, nonpregnant rats," Endocrinology, vol.145, pp. 3289-3296.

Shroff, S.G., Hibbard, J.U., and Lang, R.M., 2004, "Cardiovascular changes in preeclampsia," Semin. Nephrol, vol.24, pp. 580-587.

Shroff, S.G., MacGowan, G., Evans, C., Hu, T.C., Debrah, D.O., Mullet, S., Chen, H.H., McTiernan, C.F., and Stewart, A.F., 2004, "Troponin I protein kinase C phosphorylation sites and ventricular function," Cardiovasc. Res, vol.63, pp. 245-255.

Shroff, S.G., and MacGowan, G.A., 2003, "he myofilament force-calcium relationship and left ventricular function," Recent Res. Devel, vol.1, pp. 873-889.

Shroff, S.G., Wu, H.C., Chen, J.S., and Carroll, J.D., 2003, "Stress analysis using anatomically realistic coronary tree and plaque subject to cardiac cyclic flexion," Med. Phys, vol.30, pp. 2927-2936.

Shroff, S.G., Cholley, B.P., Lang, R.M., and Korcarz, C., 2001, "Smooth muscle relaxation and local hydraulic impedance properties of the aorta," J. Appl. Physiol, vol.90, pp. 2427-2438.

Shroff, S.G., Collins, K.A., Korcarz, C.E., Bednarz, J.E., Fentzke, R.C., Lin, H., Leiden, J.M., and Lang, R.M., 2001, "Accuracy of echocardiographic estimates of left ventricular mass in mice," Am. J. Physiol. Heart Circ. Physiol, vol.280, H1954-H1962.

Shroff, S.G., Evans, C.S., Gooch, L., Flotta, D., Lykins, D., Powers, R.W., Landsittel, D., and Roberts, J.M., 2001, "Cardiovascular system during the post partum state in women with a history of preeclampsia," Hypertension, vol.58, pp. 57-62.

Shroff, S.G., Fentzke, R.C., Korcarz, C.E., Lin, H., Leiden, J.M., and Lang, R.M., 2001, "The left ventricular stress-velocity relationship in transgenic mice expressing a dominant negative CREB transgene in the heart," J. Am. Soc. Echocardiogr, vol.14, pp. 209-218.

Shroff, S.G., Berger, D.S., Fellner, S.K., Robinson, K.A., Vlasica, K., and Godoy, I.E., 1999, "Disparate effects of three types of extracellular acidosis on left ventricular function," Am. J. Physiol, vol.276, no.Heart Circ. Physiol. 45, H585-H594.

Shroff, S.G., 1998, "Pulsatile arterial load and cardiovascular function: Facts, fiction, and wishful thinking," Threrap. Res, vol.19, pp. 59-66.

Shroff, S.G., and Lang, R.M., 1997, "Noninvasive evaluation of aortic elastic properties," in Echocardiography and Cardiovascular Function: Tools for the Next Decade, R.M. Lang, and J.E. Perez, eds., Kluwer Academic Publishers, pp. 99-122, Norwell, MA.

Shroff, S.G., Berger, D.S., Vlasica, K., Quick, C.M., and Robinson, K.A., 1997, "Ejection has both positive and negative effects on left ventricular isovolumic relaxation," Am. J. Physiol, vol.273, no.Heart Circ. Physiol. 42, H2696-H2707.

Shroff, S.G., Fentzke, R.C., Korcarz, C.E., Lin, H., Sandelski, J., Leiden, J.M., and Lang, R.M., 1997, "Evaluation of ventricular and arterial hemodynamics in anesthetized, closed-chest mice," J. Am. Soc. Echocardiogr, vol.10, pp. 915-925.

Shroff, S.G., Korcarz, C.E., Padrid, P.A., Weinert, L., and Lang, R.M., 1997, "Doppler echocardiographic reference values for healthy Rhesus monkeys under ketamine hydrochloride sedation," J. Med. Primatol, vol.26, pp. 287-298.

Shroff, S.G., Mor-Avi, V., Robinson, K.A., and Lang, R.M., 1997, "Effects of temperature on Albunex┬┐ and FS069 echocardiographic contrast agents: In-vitro investigation using ultrasonic irradiation," Echocardiography, vol.14, pp. 39-49.

Shroff, S.G., Poppas, A., Korcarz, C.E., Hibbard, J.U., Berger, D.S., Lindheimer, M.D., and Lang, R.M., 1997, "Serial assessment of cardiovascular system in normal pregnancy: role of arterial compliance and pulsatile arterial load," Circulation, vol.95, pp. 2407-2415.

Shroff, S.G., Seow, C., and Ford, L., 1997, "Detachment of low-force bridges contributes to the rapid tension transients of skinned rabbit skeletal muscle fibres," J. Physiol (London), vol.501, pp. 149-164.

Shroff, S.G., Berger, D.S., and Robinson, K.A., 1996, "Wave propagation in coupled left ventricle-arterial system: Implications for aortic pressure," Hypertension, vol.27, pp. 1079-1089.

Shroff, S.G., Cholley, B.P., Korcarz, C., and Lang, R.M., 1996, "Aortic elastic properties with transesophageal echocardiography with automated border detection: Validation according to regional differences between proximal and distal descending thoracic aorta," J. Am. Soc. Echocardiogr, vol.9, pp. 539-548.

Shroff, S.G., Fogliardi, R., Burattini, R., and Campbell, K.B., 1996, ". Fit to diastolic arterial pressure by third-order lumped model yields unreliable estimates of arterial compliance," Med. Eng. Phys, vol.18, pp. 225-233.

Shroff, S.G., Mor-Avi, V., Lang, R.M., Robinson, K.A., Korcarz, K., Ng, A.F., Vignon, P.R., and Akselrod, S., 1996, "Contrast echocardiographic quantification of regional myocardial perfusion: Validation using an isolated rabbit heart preparation," J. Am. Soc. Echocardiogr, vol.9, pp. 156-165.

Shroff, S.G., Mor-Avi, V., Robinson, K.A., Cholley, B.P., Ng, A.F., and Lang, R.M., 1996, "Echocardiographic contrast agents and left ventricular contractility: Evaluation using an isolated rabbit heart model," J. Am. Soc. Echocardiogr, vol.9, pp. 452-461.

Shroff, S.G., Poppas, A., Marcus, R.H., and Lang, R.M., 1996, "Noninvasive determination of arterial compliance," in Functional Abnormalities of the Aorta, H. Boudoulas, P. Toutouzas, and C.F. Wooley, eds., Futura Publishing Co, pp. 195-208, Armonk, NY.

Shroff, S.G., Berger, D.S., Lang, R., Marcus, R., Korcarz, C., and Miller, D., 1995, "Physiologic relevance of T-Tube model parameters with emphasis on arterial compliances," Am. J. Physiol, vol.269, no.Heart Circ. Physiol. 38, H365-H374.

Shroff, S.G., Cholley, B.P., Lang, R.M., Berger, D.S., Korcarz, C., and Didier, P., 1995, "Alterations in systemic arterial mechanical properties during septic shock: Role of fluid resuscitation," Am. J. Physiol, vol.269, no.Heart Circ. Physiol. 38, H375-H384.

Shroff, S.G., Cholley, B.P., Sandelski, J., Korcarz, C., Balasia, B.A., Jain, S., Berger, D.S., Murphy, M.B., Marcus, R.H., and Lang, R.M., 1995, "Differential effects of chronic oral antihypertensive therapies on systemic arterial circulation and ventricular energetics in African American patients," Circulation, vol.91, pp. 1052-1062.

Shroff, S.G., Saner, D.R., and Lal, R., 1995, "Dynamic micro-mechanical properties of contractile cells measured by atomic force microscopy," Am. J. Physiol, vol.269, no.Cell Physiol. 38, C286-C292.

Shroff, S.G., and Lang, R.M., 1994, "Left Ventricular Diastolic Dysfunction and Heart Failure."

Shroff, S.G., and Slinker, B.K., 1994, "The Interval-Force Relationship of the Heart: Bowditch Revisited."

Shroff, S.G., Campbell, K.B., Kirkpatrick, R.D., Tobias, A., and Taheri, H., 1994, "Series-coupled non-contractile elements are functionally unimportant in the isolated heart," Cardiovasc. Res, vol.28, pp. 242-251.

Shroff, S.G., Lang, R., Cholley, B., Korcarz, C., and Marcus, R.H., 1994, "Measurement of regional elastic properties of the human aorta: A new application of transesophageal echocardiography with automated border detection and calibrated subclavian pulse tracings," Circulation, vol.90, pp. 1875-1882.

Shroff, S.G., Mor-Avi, V., Robinson, R.A., Ng, A.F., Cholley, B.P., Marcus, R.H., and Lang, R.M., 1994, "Effects of ventricular pressure on the stability of sonicated albumin microbubbles: Evaluation using an isolated heart model," J. Am. Coll. Cardiol, vol.24, pp. 1779-1785.

Shroff, S.G., Samsel, R.W., Schmidt, G.A., Hall, J.B., Wood, L.D., and Schumacker, P.T., 1994, "Cardiovascular physiology teaching laboratories: Computer simulations vs. animal laboratories," Am. J. Physiol, vol.266, no.Adv. Physiol. Educ, S36-S46.

Shroff, S.G., Campbell, K.B., and Kirkpatrick, R.D., 1993, "Short time-scale LV systolic dynamics: Pressure- versus volume-clamps and effect of activation," Am. J. Physiol, vol.264, no.Heart Circ. Physiol. 33, H946-H959.

Shroff, S.G., Marcus, R., Bednarz, J., Coulden, R., Lipton, M., and Lang, R., 1993, "Evaluation of ultrasonic backscatter system for automated real-time endocardial boundary detection by ultrafast computed tomography," J. Am. Coll. Cardiol, vol.22, pp. 839-847.

Shroff, S.G., Campbell, K.B., and Kirkpatrick, R.D., 1991, "Short time-scale LV systolic dynamics: Expression of a common mechanism in both LV chamber and heart-muscle mechanics," Circ. Res, vol.68, pp. 1532-1548.

Shroff, S.G., Carroll, J.D., Wirth, P., and Rajfer, S.I., 1991, "Arterial mechanical properties in dilated cardiomyopathy: Aging and response to nitroprusside," J. Clin. Invest, vol.87, pp. 1002-1009.

Shroff, S.G., Chiu, C., Arand, P.W., Carroll, J.D., and Feldman, T., 1991, "Computerized algorithms for the determination of pulse wave velocities," Am. Heart J, vol.1212, pp. 1460-1470.

Shroff, S.G., D'Cruz, I.A., and Daly, D., 1991, "Left ventricular shape and size in dilated cardiomyopathy: Quantitative echocardiographic assessment," Echocardiography, vol.8, pp. 187-193.

Shroff, S.G., Jain, A., Reddy, H.K., Weber, K.T., and Janicki, J.S., 1991, "Relation between mixed venous oxygen saturation and cardiac index: Nonlinearity and normalization for oxygen uptake and hemoglobin," Chest, vol.99, pp. 1403-1409.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1991, "Mechanical and energetic behavior of the intact left ventricle," in The Heart and Cardiovascular System, H.A. Fozzard, E. Haber, R.B. Jennings, A.M. Katz, and H.E. Morgan, eds., Raven Press, pp. 129-150, New York.

Shroff, S.G., Slinker, B.K., and Kirkpatrick, R.D., 1991, "Left ventricular function depends on previous beat ejection but not previous beat pressure load," Circ. Res, vol.69, pp. 1051-1057.

Shroff, S.G., Spencer, K.T., Lang, R.M., Neumann, A., and Borow, K.M., 1991, "Doppler and electromagnetic comparisons of instantaneous aortic flow characteristics in primates," Circ. Res, vol.68, pp. 1369-1377.

Shroff, S.G., Naegelen, D.R., and Clark, W.A., 1990, "Relation between left ventricular systolic resistance and contractile rate processes," Am. J. Physiol, vol.258, no.Heart Circ. Physiol. 27, H381-H394.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1990, "Coupling of the left ventricle with the systemic arterial circulation," in McDonald's Blood Flow in Arteries, 3rd edition, W.W. Nichols, and M.F. O'Rourke, eds., Edward Arnold, pp. 343-359, London.

Shroff, S.G., and Motz, W., 1989, "Left ventricular systolic resistance in rats with hypertension and hypertrophy," Am. J. Physiol, vol.257, no.Heart Circ. Physiol. 26, H386-H394.

Shroff, S.G., D'Cruz, I.A., Janicki, J.S., Jain, A., Reddy, H.K., and Lakier, J.B., 1989, "Differences in the shape of the normal, cardiomyopathic and volume overloaded human left ventricle," J. Am. Soc. Echocard, vol.2, pp. 408-414.

Shroff, S.G., Jalil, J.E., Doering, C.W., Janicki, J.S., Pick, R., and Weber, K.T., 1989, "Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle," Circ. Res, vol.64, pp. 1041-1050.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1989, "Ventricular interdependence," in Heart-Lung Interactions in Health and Disease, S. Cassidy, and S.M. Scharf, eds., Marcel Dekker Inc, pp. 283-307, New York.

Shroff, S.G., Narayan, S., Janicki, J.S., Pick, R., and Weber, K.T., 1989, "Myocardial collagen and mechanics after preventing hypertrophy in hypertensive rats," Am. J. Hypertension, vol.2, pp. 675-682.

Shroff, S.G., Weber, K.T., Janicki, J.S., Pick, R., Chen, R.M., and Bashey, R.I., 1988, "Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium," Circ. Res, vol.62, pp. 757-765.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1987, "Functional significance of the pericardium," in Simulation and Control of the Cardiac System (Vol. 2), R. Beyar, and S. Sideman, eds., CRC Press Inc, pp. 31-42, Boca Raton.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1987, "Influence of the pericardium in patients with chronic heart failure: Effects of upright exercise," Heart Failure J, vol.3, pp. 20-30.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1987, "Physiologic response to the inotropic and vasodilator properties of enoximone," Am. J. Cardiol, vol.60, 15C-20C.

Shroff, S.G., Janicki, J.S., Weber, K.T., and Loscalzo, J., 1987, "Cardiac dynamics and extracardiac pressure in dogs," Cardiovasc. Res, vol.21, pp. 230-239.

Shroff, S.G., Weber, K.T., Clark, W.C., and Janicki, J.S., 1987, "Physiological vs. pathological hypertrophy and the pressure overloaded myocardium," J. Cardiovasc. Pharm, vol.10, S37-S49.

Shroff, S.G., Weber, K.T., Janicki, J.S., Pick, R., Abrahams, C., Bashey, R.I., and Chen, R.M., 1987, "Collagen in the hypertrophied pressure-overloaded myocardium," Circulation, vol.75, I40-I47.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1986, "Instrumentation for monitoring respiratory gas exchange," in Cardiopulmonary Exercise Testing, J.S. Janicki, and K.T. Weber, eds., W.B. Saunders Co, pp. 113-125, Philadelphia.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1986, "Instrumentation for monitoring respiratory gas transport," in Cardiopulmonary Exercise Testing, J.S. Janicki, and K.T. Weber, eds., W.B. Saunders Co, pp. 125-137, Philadelphia.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1986, "Left ventricular systolic resistance and its role in coupling the ventricle to the arterial circulation," in Ventricular/Vascular Coupling, F.C. Yin, ed., Springer-Verlag, pp. 240-261, , New York.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1986, "Influence of extracardiac forces on the cardiopulmonary unit," in Ventricular-Vascular Coupling, F.C. Yin, ed., Springer-Verlag, pp. 262-287, New York.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1986, "Measurement of ventricular function in the experimental laboratory," in The Heart and Cardiovascular System, H.A. Fozzard, E. Haber, R.B. Jennings, A.M. Katz, and H.E. Morgan, eds., Raven Press, pp. 865-886, New York.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1986, "The heart as a mechanical pump," in Cardiopulmonary Exercise Testing, J.S. Janicki, and K.T. Weber, eds., W.B. Saunders Co, pp. 34-56, Philadelphia.

Weber, K.T., Janicki, J.S., and Shroff, S.G., 1986, "The mechanics and energetics of ventricular contraction," in Cardiopulmonary Exercise Testing, J.S. Janicki, and K.T. Weber, eds., W.B. Saunders Co, pp. 57-76, Philadelphia.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1985, "Evidence and quantitation of left ventricular systolic resistance," Am. J. Physiol, vol.249, no.Heart Circ. Physiol. 18, H358-H370.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1985, "Left ventricular chamber resistance and its physical basis," Proc. 38th ACEMB, p. 10.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1985, "Left ventricular performance and its systolic mechanical properties," in Simulation and Imaging of the Cardiac System, R. Beyar, and S. Sideman, eds., Martinus Nijhoff, pp. 64-72, Boston.

Shroff, S.G., Laskey, W.K., Kussmaul, W.G., Martin, J.L., Hirshfeld, J.W., and Kleaveland, J.P., 1985, "Characteristics of vascular hydraulic load in heart failure," Circulation, vol.72, pp. 61-71.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1984, "End-systolic relations: Their usefulness and limitations in assessing left ventricular contractile state," Int. J. Cardiol, vol.5, pp. 253-259.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1983, "Left ventricular systolic dynamics in terms of its chamber mechanical properties," Am. J. Physiol, vol.245, no.Heart Circ. Physiol. 14, H110-H124.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1983, "The importance of internal resistance in the description of left ventricular mechanics," Bull. Philadelphia Physiol. Soc, vol.2, pp. 32-43.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1983, "LV performance and its systolic mechanical properties," Proc. 36th ACEMB, p. 121.

Shroff, S.G., Weber, K.T., and Janicki, J.S., 1983, "Mechanical and structural aspects of the hypertrophied human myocardium," in Cardiac Hypertrophy in Hypertension (Perspectives in Cardiovascular Research, Vol. 8), R.C. Tarazzi, ed., Raven Press, pp. 201-210, New York.

Shroff, S.G., Weber, K.T., Janicki, J.S., and Laskey, W., 1983, "The mechanisms of ventricular function," Hosp. Practice, vol.18, pp. 113-117.

Shroff, S.G., Weber, K.T., Janicki, J.S., and Lickoff, M.J., 1983, "The cardio-pulmonary unit: The body's gas transport system," in Clinics in Chest Med. (Vol. 4), pp. 101-110.

Shroff, S.G., Weber, K.T., Janicki, J.S., and Pearlman, E.S., 1983, "Shape and structure of the normal and failing human heart," in Myocardial Hypertrophy and Failure (Perspectives in Cardiovascular Research, Vol. 7), N.E. Alpert, ed., Raven Press, pp. 85-102, New York.

Shroff, S.G., Weber, K.T., Janicki, J.S., Likoff, M.J., and Andrews, V., 1983, "hronic cardiac failure: Pathophysiologic and therapeutic considerations," Triangle, vol.22, pp. 1-9.

Shroff, S.G., Weber, K.T., Janicki, J.S., Likoff, M.J., and St. John Sutton, M.G., 1983, "The right ventricle: Physiologic and pathophysiologic considerations," J. Crit. Care Med, vol.11, pp. 323-328.

Shroff, S.G., Weber, K.T., Scott, G., and Janicki, J.S., 1983, "The normal regulation of coronary blood flow," in Coronary Artery Spasm and Thrombosis (Cardiovasc. Clinics, Vol. 14/1), S. Goldberg, ed., F.A. Davis Co, pp. 9-16, Philadelphia.

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1982, "A model of left ventricular systolic dynamics," Proc. 35th ACEMB, p. 63.

Shroff, S.G., Weber, K.T., Janicki, J.S., Hunter, W.C., Pearlman, E.S., and Fishman, A.P., 1982, "The contractile behavior of the heart and its functional coupling to the circulation," Prog. Cardiovasc. Dis. XXIV, pp. 375-400.

Shroff, S.G., 1981, "Left Ventricular Dynamics Described in Terms of its Visco-Elastic Chamber Properties."

Shroff, S.G., Janicki, J.S., and Weber, K.T., 1981, "Regional and global shape and size of the intact myocardium," Fed. Proc, vol.40, pp. 2005-2010.

Shroff, S.G., Janicki, J.S., Weber, K.T., Gochman, R.F., and Geheb, F.J., 1981, "Three-dimensional myocardial and ventricular shape: A surface representation," Am. J. Physiol, vol.241, no.Heart Circ. Physiol. 10, H1-H11.

Shroff, S.G., Weber, K.T., Janicki, J.S., and Fishman, A.P., 1981, "Fishman AP. Contractile mechanics and interaction of the right and left ventricles," Am. J. Cardiol, vol.47, pp. 885-896.

Shroff, S.G., Weber, K.T., Reichek, N., and Janicki, J.S., 1981, "The pressure overloaded heart: Physiological and clinical correlates," in Heart in Hypertension, B. Strauer, ed., Springer-Verlag, pp. 297-305, Munich.

Shroff, S.G., 1976, "Aspects of Ultrasonic Tracking of Body Motions."

Shroff, S.G., Milner, M., and Kitai, R., 1976, "Ultrasonic tracking of body motions," Proc. XI Int. Conf. Med. Biol. Eng. XIII, pp. 287-296.

Chen, E.A., Korcarz, C.E., Giradet-Nendaz, G., Weinert, L., Lang, R.M., and Shroff, S.G., "(in preparation) Hormone replacement therapy and systemic arterial properties in postmenopausal women."

He, Y., and Shroff, S.G., "(in preparation) Independent and simultaneous control of pressure and flow waveforms in the setting of ex vivo vascular culture: A model-based study.."

Smith, S.H., and Shroff, S.G., "(in preparation) Dynamic crossbridge behavior in mice expressing mutant cardiac troponin I (CTnIS43,45A)."

2009, "A Priori Identifiability Analysis of Cardiovascular and Sarcomeric Function Models," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "Altered Crossbridge Dynamics in Mice Expressing Constitutively Phosphorylated Cardiac Troponin I," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "Arterial Vascular Properties and Function during the Post-Partum State in Women with History of Preeclapsia," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "Impact of Cyclic Mechanical Stretch on Muscel Stem Cell-Dertived Cardiomyocyte 3-D Engineered Tissue," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "In Vivo Acetylation-Induced Regulation of Myofilament Calcium Sensitivity," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "Independent Regulation of Calcium Sensitivity in the Mouse Heart by Myofilament Acetylation and Protein Kinase A-Induced Phosphorylation," American Heart Association, Scientific Sessions 2009, Orlando, FL.

2009, "Post-Translational Regulation of Myofilament Calcium Sensitivity: Phosphorylation vs. Acetylation," BMES Annual Fall Meeting, Pittsburgh, PA.

2009, "Strain Energy Functions for Biaxial Vascular Wall Mechanics of Small Renal Arteries," BMES Annual Fall Meeting, Pittsburgh, PA.

2008, "Acetylation of Cardiac Sarcomeric Proteins Regulates Myofilament Contractile Activity," BMES Annual Fall Meeting, St. Louis, MO.

2008, "Determinants of Relaxin-Induced Changes in Passive Compliance of Small Renal Arteries," BMES Annual Fall Meeting, St. Louis, MO.

2008, "Determinants of Relaxin-Induced Changes in Passive Compliance of Small Renal Arteries: Geometric vs. Compositional Remodeling," 5th International Conference on Relaxin & Related Peptides, Maui, HI.

2008, "Differential Effects of LV Pacing Sites on Ventricular Mechanics in Canine Model of Dyssynchrony," BMES Annual Fall Meeting, St. Louis, MO.

2008, "Effects of Chronic Intermittent Hypoxia on Cardiac Muscle Force and Calcium Transients in Mice," BMES Annual Fall Meeting, St. Louis, MO.

2008, "Relaxin Regulates Arterial Wall Structure and Composition," 55th Annual Meeting of the Society of Gynecologic Investigation, San Diego, CA.

2008, "Relaxin-Induced Compositional and Geometric Remodeling of Small Renal Arteries," 5th International Conference on Relaxin & Related Peptides, Maui, HI.

2007, "Effects of Intermittent Hypoxia on Cardiac Muscle Contractile Function in Mice," BMES Annual Fall Meeting 2007, LosAngeles, CA.

2007, "Role of Src in Pressure-Induced Regulation of Arterial Gap Junctions: An Ex Vivo Study," BMES Annual Fall Meeting 2007, LosAngeles, CA.

2007, "Ventricular Function in Mice Expressing Constitutively Phosphorylated Cardiac Troponin I," BMES Annual Fall Meeting, Los Angeles, CA.

2006, "PKC-Induced Troponin I Phosphorylation and the Dynamic Force-Length Relationship in Mouse Myocardium," BMES Annual Fall Meeting, Chicago, IL.

2006, "Pressure-Calcium Relationships in Perfused Mouse Hearts," BMES Annual Fall Meeting, Chicago, IL.

2006, "Relaxin is Essential for Systemic Vasodilation and Increased Arterial Compliance During Early Pregnancy in Conscious Rats," 53rd Annual Meeting of the Society of Gynecologic Investigation, Toronto, Canada.

2006, "Relaxin Mediates Systemic Vasodilation and Increased Global Arterials in Early Pregnancy," 53rd Annual Meeting of the Society of Gynecologic Investigation, Toronto, Canada.

2006, "Relaxin Mediates Systemic Vasodilation and Increased Global Arterials in Early Pregnancy," BMES Annual Fall Meeting, Chicago, IL.

2006, "Role of Contraction Dyssynchrony on Global Left Ventricular Mechanics and Performance," BMES Annual Fall Meeting, Chicago, IL.

2005, "Evidence that Relaxin is a Vascular-Derived, Locally-Acting Relaxing and Compliance Factor," 52nd Annual Meeting of the Society of Gynecologic Investigation, Los Angeles, CA.

2004, "Relaxin Modifies Systemic Arterial Resistance and Compliance in Conscious, Nonpregnant Rats," Beckman Scholars Research Symposium.

1994, "Panelist in a workshop: Advanced Cardiovascular Mechanics.," Cardiologia, Pontifica Universidad Catholica de Chile, Santiago, Chile.

1994, "Panelist in a workshop: Cardiovascular Summit on Systolic and Diastolic Function," The 11th International Conference of the Cardiovascular System Dynamics Society, San Francisco, CA.

1980, "Prediction of Peak Isovolumetric Pressure in Ejecting Left Ventricle," American Heart Association 53rd Scientific Sessions, Miami, FL.

1980, "Systolic Elastance and Resistance in Ejecting Left Ventricle," Federation of American Societies for Experimental Biology 64th Annual Meeting, Anaheim, CA.

1980, "Three-dimensional Myocardial Shape," American Heart Association 53rd Scientific Sessions, Miami, FL.

1981, "Prediction of Peak isovolumetric Pressure in Intact Dog," American Heart Association 54th Scientific Sessions, Dallas, TX.

1982, "A Elastance-Resistance Model of Left Ventricular Systolic Dynamics," Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD.

1982, "The Importance of Internal Resistance in the Description of Left Ventricular Mechanics," Symposium on Ventricular Mechanics, Philadelphia Physiological Society, Philadelphia, PA.

1982, "The importance of Left Ventricular Chamber Resistance in Determining Instantaneous Pressure and Flow," American Heart Association 55th Scientific Sessions, Dallas, TX.

1983, "Arterial Load at Rest and Exercise in Chronic Cardiac Failure," American Heart Association 56th Scientific Sessions, Anaheim, CA.

1983, "Effects of Exercise and Inotropic Stimulation on Hydraulic Load in Patients With or Without Cardiac Failure," American Federation of Clinical Research, Washington, DC.

1983, "Engineering Approach to Quantifying Left Ventricular Systolic Mechanical Behavior," Pritzker Institute of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL.

1983, "Evidence and Characterization of Left Ventricular Resistive Behavior," American Heart Association 56th Scientific Sessions, Anaheim, CA.

1983, "Left Ventricular Systolic Mechanical Properties," Division of Cardiology, University of Virginia, Charlottesville, VA.

1983, "The relation Between Left Ventricular Efficiency and Arterial Load," American Federation of Clinical Research, Washington, DC.

1984, "Current Approaches to Analyzing Ventriculo-Arterial Coupling," Department of Physiology, Loyola University, Chicago, IL.

1984, "Shape and Function of Dilated Hypertrophied Heart," . First Symposium on Myocardial Hypertrophy, Howard University & NASA Life Sciences Division, Washington, DC.

1985, "Importance of Quantifying Left Ventricular Resistance in hypertrophy due to systemic hypertension," American College of Cardiology, 34th Annual Scientific Session, Anaheim, CA.

1985, "Left Ventricular Chamber Resistance and its Physical Basis," Symposium on the Current Concepts in Cardiac Dynamics, Conference on Engineering in Medicine and Biology, Chicago, IL.

1985, "Shape, Size and Contractility of the Cardiomyopathic Left Ventricle," American Heart Association, 58th Scientific Sessions, Washington, DC.

1986, "Aortic Compliance: Methods and Clinical Applications," American Heart Association 59th Scientific Sessions, Dallas, TX.

1986, "Isomyosin and Global Mechanical Properties of the Left Ventricle," Symposium on Myosin and Myocardial Mechanic. Chicago Heart Associations, Chicago, IL.

1986, "Left Ventricular Systolic Resistance and Chamber Dynamics," Symposium on Cardiac Mechanics, Association for the Advancement of Medical Instrumentation, Chicago, IL.

1986, "Quantitative Comparison of the Shape of Normal, Cardiomyopathic, and Volume-Overloaded Left Ventricles: A 2-D Echocardiographic Study," American Heart Association 59th Scientific Sessions, Dallas, TX.

1987, "Age, Arterial Load and Response to Vasodilator Therapy in Heart Failure," American Heart Association 60th Scientific Sessions, Anaheim, CA.

1987, "An Overview & Evaluation of Various Research Technologies for Use in Small Species: Electromagnetic, Ultrasonic (Transit-Time), Ultrasonic (Doppler), Thermal Dilution," Instrumentation Tutorial on Blood Flow Measurements in Small Animals, FASEB meeting, Washington, DC.

1987, "Computerized Algorithms for the Determination of Pulse Wave Velocities," American Heart Association 60th Scientific Sessions, Anaheim, CA.

1987, "Homomorphic Analysis: A New Technique to Quantify Discrete Arterial Reflections," American Heart Association 60th Scientific Sessions, Anaheim, CA.

1987, "Isomyosin and Global Mechanical Properties of the Left Ventricle," Symposium on Ventricular Mechanics, IEEE Engineering in Medicine and Biology, Boston.

1987, "Isomyosin and Systolic Mechanical Properties of the Intact, Hypertrophied Left Ventricle," American Heart Association 60th Scientific Sessions, Anaheim, CA.

1987, "Modeling of Left Ventricular Systolic Dynamics," Department of Bioengineering, University of Illinois, Chicago, IL.

1987, "Therapeutic Response in Cardiac Index as Assessed by Mixed Venous Oxygen Saturation in Heart Failure," American Heart Association 60th Scientific Sessions, Anaheim, CA.

1988, ""Lead Pipe" Aorta: Pulse Wave Velocity in the Very Elderly with Aortic Stenosis," American Heart Association 61st Scientific Sessions, Washington, DC.

1990, "Clinical Implications of Left Ventricular Systolic Resistance," Philadelphia Heart Institute, Philadelphia, PA.

1990, "Information Retrievable From Left Ventricular Pressure-Volume Relations," Department of Physiology, University of Missouri, Columbia, MS.

1990, "Information Retrievable From Left Ventricular Pressure-Volume-Flow Relations," Division of Cardiology, University of Cincinnati, Cincinnati, OH.

1990, "Left Ventricular Systolic Dynamics. Section of Cardiology," Bowman Gray School of Medicine, Winston-Salem, NC.

1990, "Structure-Function Correlation Using an Interpretive Model of Left Ventricular Systolic Dynamics," Department of Biomedical Engineering, University of Tennessee, Memphis, TN.

1991, "A Method to Quantify Activation-Independent Global Left Ventricular Systolic Dynamics," Federation of American Societies for Experimental Biology 75th Annual Meeting, Atlanta, GA.

1991, "Aortic Characteristic Impedance and Pulse Wave Velocity: A Comparative Study of Hypertension and Cardiomyopathy," American Heart Association 64th Scientific Sessions, Anaheim, CA.

1991, "Contractile Dynamics of the Left Ventricle: Effect of Volume and Activation," American Heart Association 64th Scientific Sessions, Anaheim, CA.

1991, "Global Arterial Compliance: Definition, Methods of Estimation and Physiological Role," Imaging Systems Division, Hewlett-Packard Company, Andover, MA.

1991, "Identification of Proximal Arterial Mechanical Properties Independent of Wave Reflections," American Heart Association 64th Scientific Sessions, Anaheim, CA.

1991, "Left Ventricular Systolic Resistance in Hypertensive Hypertrophy," Department of Medicine, University of Chicago, Chicago, IL.

1991, "LV Systolic Resistance: Definition, Measurement and Physiologic Relevance," Department of Surgery, University of Chicago, Chicago, IL.

1991, "Regional Arterial Mechanical Properties: Nitroprusside Versus Non-Pharmacologically Mediated Changes in Distending Pressure," American Heart Association 64th Scientific Sessions, Anaheim, CA.

1991, "Windkessel-Based Estimates of Arterial Compliance: Effect of Arterial Wave Reflections," American Federation for Clinical Research, Midwest Section, Chicago, IL.

1992, "Assessment of Regional Aortic Mechanical Properties Using Transesophageal Echocardiography With Automated Border Detection and Subclavian Pulse Tracings," American Heart Association, 65th Scientific Sessions, New Orleans, LA.

1992, "Contribution of Distal Processes Towards Central Aortic Compliance," American Heart Association, 65th Scientific Sessions, New Orleans, LA.

1992, "Differential Response of Aortic Compliance and Pulse Wave Velocity to Nitroprusside in Hypertensive Patients," American Heart Association, 65th Scientific Sessions, New Orleans, LA.

1992, "Effect of Temperature on Short Time-Scale Left Ventricular Contractile Dynamics," American Heart Association, 65th Scientific Sessions, New Orleans, LA.

1992, "Short Time-Scale Systolic Dynamics of the Intact Left Ventricle: A New Method to Extract the Kinetic Parameters of Contraction," Department of Physiology & Biophysics, University of Illinois at Chicago, Chicago, IL.

1993, "2,3-Butanedione Monoxime and Hydrogen Ion Inhibit the Same Transition of the Skeletal Muscle Crossbridge Cycle," American Heart Association, 66th Scientific Sessions, Atlanta, GA.

1993, "Differential Effects of Anti-Hypertensive Agents on the Arterial Circulation," American Heart Association, 66th Scientific Sessions, Atlanta, GA.

1993, "Estimation of Regional Arterial Compliance Using Acoustic Quantification Technology," Imaging Systems Division, Hewlett-Packard Company, Andover, MA.

1993, "Global LV Systolic Dynamics and Myocardial Cellular Processes," Cardiology Section, Rush-Presbyterian Medical Center, Chicago, IL.

1993, "Left Ventricular Mass by M-mode Echocardiography: Evaluation of Accuracy and Geometric Assumptions Using Ultrafast CT and 2D Echocardiography," American College of Cardiology, 42nd Scientific Sessions, Anaheim, CA.

1993, "Regional and Global Arterial Mechanical Properties in Patients with Marfan Syndrome," Cardiology Section, Washington University, St. Louis, MO.

1994, "2,3-Butanedione Monoxime Increases LV Diastolic Chamber Elastance," American Heart Association, 67th Scientific Sessions, Dallas, TX.

1994, "Albunex Microspheres and Left Ventricular Contractility: Load and Heart Rate Independent Analysis Using an Isolated Rabbit Heart," American Society of Echocardiography, 5th Scientific Sessions, San Francisco, CA.

1994, "Arterial Compliance: Physical Basis and Physiological Relevance," Department of Physics and Cardiology Section, Washington University, St. Louis, MO.

1994, "Assessment of Aortic Elastic Properties Using Transesophageal Echocardiography With Automated Border Detection," American Society of Echocardiography, 5th Scientific Sessions, San Francisco, CA.

1994, "Atomic Force Microscopy of Atrial Cells: Local Visco-Elastic Mechanical Properties and Imaging of Cytoskeleton," Biophysical Society, 38th Annual Meeting, New Orleans, LA.

1994, "Differential Effects of Anti-Hypertensive Agents on the Arterial Circulation," International Society of Hypertension, 15th Scientific Meeting, Melbourne, Australia.

1994, "Differential effects of Ramipril, Nifedepine and Atelenol on Cardiac Function in African-American Hypertensive Patients," International Society of Hypertension, 15th Scientific Meeting, Melbourne, Australia.

1994, "Effects of FS069 New Contrast Agent on Left Ventricular Contractility: Load and Rate Independent Analysis Using an Isolated Rabbit Heart," . American Heart Association, 67th Scientific Sessions, Dallas, TX.

1994, "Effects of Left Ventricular Pressure on Albunex Microspheres: Evaluation Using an Isolated Rabbit Heart Model," American Society of Echocardiography, 5th Scientific Sessions, San Francisco, CA.

1994, "Effects of Reflections and Wave Velocity on Aortic Pressure and Flow," American Heart Association, 67th Scientific Sessions, Dallas, TX.

1994, "Local Visco-Elastic Mechanical Properties of Atrial Cells Quantified by Atomic Force Microscopy," Cardiology Section, Rush-Presbyterian Medical Center, Chicago, IL.

1994, "Paradoxical Effect of Intravenous Diltiazem on Aortic Elastic Properties," American College of Cardiology, 43rd Scientific Sessions, Atlanta, GA.

1994, "Stability of Albunex Microspheres Under Ultrasonic Irradiation: An In-Vitro Study," American Society of Echocardiography, 5th Scientific Sessions, San Francisco, CA.

1994, "Systemic Arterial Properties in Normal Pregnancy," American Heart Association, 67th Scientific Sessions, Dallas, TX.

1995, "Characterization of Arterial Circulation in Hypertension-Complicating Pregnancy," American Heart Association, 68th Scientific Sessions, Anaheim, CA.

1995, "Dynamic Properties of Contractile Cells Measured by Atomic Force Microscopy," Department of Molecular Physiology & Biophysics and Department of Pathology, University of Vermont, Burlington, VT.

1995, "Effects of Reflections and Wave Velocity on Left Ventricular Isovolumic Relaxation," American Heart Association, 68th Scientific Sessions, Anaheim, CA.

1995, "Interaction Between Reflection and Wave Velocity Effects on Aortic Pressure," American Heart Association, 68th Scientific Sessions, Anaheim, CA.

1996, "2,3-Butanedione Monoxime (BDM) Speeds Left Ventricular Isovolumic Relaxation," American Heart Association, 69th Scientific Sessions, New Orleans, LA.

1996, "Frequency of Minimum Elastance (Stiffness) Does not Uniquely Correspond to Crossbridge Kinetics," American Heart Association, 69th Scientific Sessions, New Orleans, LA.

1996, "Positive and Negative Effects of Ejection on Relaxation," American Heart Association, 69th Scientific Sessions, New Orleans, LA.

1997, "Arterial Compliance: Methods for Assessment and Clinical Relevance," New Frontiers in Echocardiography: Integrating Recent Advances into Clinical Practice (Conference), Omni Chicago Hotel, Chicago, IL.

1997, "Biomechanical Applications of Atomic Force Microscopy," Department of Cardiovascular Dynamics, National Cardiovascular Center Research Institute, Osaka, Japan.

1997, "Disparate Effects of Three Types of Extracellular Acidosis on Left Ventricular Function," American Heart Association, 70th Scientific Sessions, Orlando, FL.

1997, "Dynamic Micromechanical Properties of Contractile Cells," Scanning Probe Microscopy (1997 meeting), Chicago, IL.

1997, "Gender Disparities in Arterial System Properties in Sustained and Daytime Hypertension," American Heart Association, 70th Scientific Sessions, Orlando, FL.

1997, "Keynote Speech at the Third Conference on Noninvasive Monitoring of Cardiovascular Hemodynamics," Tokyo, Japan.

1997, "Micromechanics and Biospecific Force Sensing Using Atomic Force Microscopy," Center for Biomedical Engineering, Columbia University, New York, New York.

1997, "Pulsatile Arterial Load and Cardiovascular Function: Facts, Fiction, and Wishful Thinking," Department of Medicine, Columbia University Medical School, New York, New York.

1998, "Influences of Contractile Activity and Passive Volume Changes on Cyclic Variations in Myocardial Integrated Backscatter," American Heart Association, 71st Scientific Sessions, Dallas, TX.

1998, "Pulsatile Arterial Load and Cardiovascular Function," Department of Bioengineering, Northwestern University, Chicago, IL.

1998, "Pulsatile Arterial Load and Cardiovascular Function," Division of Cardiology, Allegheny General Hospital, Allegheny University of Health Sciences, Pittsburgh, PA.

1998, "Regional Vascular Stiffness Changes and Isolated Systolic Hypertension," American Heart Association, 71st Scientific Sessions, Dallas, TX.

1998, "Vascular Stiffness and Cardiovascular Function," Departments of Surgery and Physiology, University of South Florida, Tampa, FL.

1999, "A Novel Simulation-Based Environment for Teaching Physiology," Association of Chairs of Departments of Physiology, Fall Retreat, Indian Wells, CA.

1999, "Left Ventricular Mechanics in Transgenic Mice Expressing Slow Skeletal Troponin I in the Heart," American Heart Association, 72nd Scientific Sessions, Atlanta, GA.

1999, "Pulsatile Arterial Load and Cardiovascular Function," Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.

1999, "SIMBIOSYS: An Interactive, Computer-Based Simulation Program for Teaching Physiology," Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.

2000, "Do Recent Advances in Ultrasound Imaging Improve the Accuracy of Left Ventricular Mass Measurements in Mice?," American College of Cardiology, 49th Annual Scientific Session, Anaheim, CA.

2000, "Novel Quantitative Tools for the Assessment of Whole Heart Function," Symposium: "Experimental Models and Novel Investigative Approaches to the Study and Treatment of Heart Failure," American College of Cardiology 49th Annual Scientific Session, Anaheim, CA.

2000, "Peripheral Circulation Contributes Significantly to the Increased Global Arterial Compliance in Normal Pregnancy," American Heart Association, 73rd Scientific Sessions, New Orleans, LA.

2000, "Pulsatile Arterial Load and Cardiovascular Function," Research Conference, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, PA.

2000, "Serial Assessment of the Cardiovascular System in Normal Pregnancy: Role of Pulsatile Arterial Load," FASEB Summer Research Conference: "Perinatal Regulation of the Cardiovascular System", Copper Mountain, CO.

2000, "SIMBIOSYS: A Computer-Based Environment for Teaching Physiology, Session: "Simulation Tools for Teaching Biology to Engineers"," American Society for Engineering Education Annual Conference, St. Louis, MO.

2001, "Dysfunction in Transgenic Perfused Mouse Hearts Expressing Mutant Troponin I Lacking Protein Kinase C Phosphorylation Sites is Dependent on Decreased Perfusate Calcium," American Heart Association, 74th Scientific Sessions, Anaheim, CA.

2001, "Noninvasive Techniques for In Vivo Measurements of Vascular Mechanical Properties," Research Conference, Lenox Hill Heart and Vascular Institute of New York, New York, NY.

2002, "Ca2+-Dependent Positive Inotropy with Preserved Relaxation in Perfused Hearts from Troponin I Transgenic Mice Lacking PKC Phosphorylation Sites," American Heart Association, 75th Scientific Sessions, Chicago, IL.

2003, "A Novel Simulation-Based Environment for Teaching Physiology," Cardiology Research Conference, The University of Tennessee Health Science Center, Memphis, TN.

2003, "An Engineer-Physiologist: Making the Connection Between Macro and Micro Worlds," Cardiology Grand Rounds, The University of Tennessee Health Science Center, Memphis, TN.

2003, "An Engineer-Physiologist: Making the Connection Between Macro and Micro Worlds," Cardiovascular Research Conference, The University of Wisconsin, Madison, WI.

2003, "In-Vivo Systolic Dysfunction Without Relaxation Abnormalities in Troponin I Transgenic Mice," American Heart Association, 76th Scientific Sessions, Orlando, FL.

2003, "Potential Role of Vascular Stiffness in Preeclampsia," ToxTalk -Preeclampsia Symposium, Mill Valley, CA.

2003, "Pulsatile Arterial Load and cardiovascular Function: Facts, Fiction, and Wishful Thinking," Cardiovascular Medicine Grand Rounds, The University of Wisconsin, Madison, WI.

2003, "Relaxin and Cardiovascular Function," Department of VCAPP, Washington State University, Pullman, WA.

2003, "Relaxin Modifies Both Steady and Pulsatile Loads in Conscious, Nonpregnant Rats," NIH Symposium, Orlando, FL.

2004, "Aging, Vascular Stiffness, and Cardiovascular Function," National Institutes of Health.

2004, "An Engineer-Physiologist: Making the Connection Between Macro and Micro Worlds," Department of Medical Physiology, Texas A&M University, College Station, TX.

2004, "Atrial and Ventricular Remodeling," Cardiac Mechanics Working Group, Medtronic, Inc, Minneapolis, MN.

2004, "Dynamic Elastance and Interactance: New Concepts for Describing Left Ventricular Pressure-Volume Relationships," Cardiovascular System Dynamics Society, Banff, Canada.

2004, "Dynamic Systems: A Physiological Perspective," Symposium, Northwestern University, Chicago, IL.

2004, "Evidence that Relaxin is a Vascular-Derived, Locally-Acting Relaxing and Compliance Factor," Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, Wyoming.

2004, "Molecular Modulation of Myofilamental Calcium Sensitivity for Improving Left Ventricular Contractile State," Department of Physiology and Cell Biology, Ohio State University, Columbus, OH.

2004, "Pulsatile Shear Stress and Endothelial Function," Argonne National Laboratory, Chicago, IL.

2004, "Recombinant Human Relaxin (rhRLX) Modifies Systemic Arterial Properties in Conscious Rats Irrespective of Gender, but in a Biphasic Fashion," Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, Wyoming.

2004, "Simulation-Based Physiology Teaching material," Department of Medical Physiology and Department of Bioengineering, Texas A&M University, College Station, TX.

2004, "Teaching Dynamic Systems Concepts in the Context of Physiology," BMES Annual Fall Meeting, Philadelphia, PA.

2004, "Troponin I Phosphorylation and Left Ventricular Function," Department of VCAPP, Washington State University, Pullman, WA.

2005, "Multiphase Fluid Dynamics: Application to the Analysis of Atherosclerosis Initiation," Invited Seminar, Argonne National Laboratory, Argonne, IL.

2005, "Relaxin and Arterial Vascular Function," National Institutes of Health.

2005, "Role of Calcium Sensitizers in Inotropic Therapy in Heart Failure," Invited Seminar, Cardiology Section, Department of Medicine, University of Chicago, Chicago, IL.

2005, "Systemic Vascular Compliance in Normal Pregnancy and Preeclampsia: Facts and Wishful Thinking," Invited Lecture, NASSHP & ERIPED Annual Scientific Meeting, Wheeling, WV.

2005, "Vascular Stiffness and Cardiovascular Function," Invited Symposium Participant, American Heart Annual Scientific Meeting, Dallas, TX.

2006, "Clinical/Medical Experiences in Undergraduate Biomedical Engineering Education," Symposium Chair/Invited Speaker, Biomedical Engineering Society Annual Meeting, Chicago, IL.

2006, "Models of the Cardiovascular System and Its Control: Development to Clinical Application," Invited Speaker, 5th International Conference on Complexity in Acute Illness, Washington, DC.

2006, "Molecular Modulation of Left Ventricular Contractile State," Invited Seminar, McGowan Institute for Regenerative Medicine and Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA.

2006, "Noninvasive Methods for the Assessment of Cardiovascular Disease," Invited Talk, Symposium organized by Omron, Inc. at the American Heart Association Annual Conference, Chicago, IL.

2006, "Role of Myofibrillar Protein Acetylation in Regulating Cardiac Muscle Contraction," Invited Seminar, Cardiothoracic Surgery Section, Department of Surgery, University of Chicago, Chicago, IL.

2006, "Systemic Arterial Circulation in Normal and Preeclamptic Pregnancy," Invited Talk, International Society for the Study of Hypertension in Pregnancy, Lisbon, Portugal.

2007, "A Novel Simulation-Based Environment for Teaching Physiology," Invited Seminar, Department of Cell & Developmental Biology and Anatomy, University of South Carolina, Columbia, SC.

2007, "An Engineer-Physiologist: Making the Connection Between Macro and Micro Worlds," Invited Seminar, Department of Chemical Engineering, University of South Carolina, Columbia, SC.

2007, "Cardiac Troponin I Phosphorylation and Cardiac Function," . Invited Seminar, Department of Physiology, University of Cincinnati, Cincinnati, OH.

2007, "Class-II Histone Deacetylases Regulate Myofilament Calcium Sensitivity in the Mouse Heart," American Heart Association, 80th Scientific Sessions, Orlando, FL.

2007, "Differential Effects of Left Ventricular Pacing Sites in a Canine Model of Dyssynchrony," Midwest Biomedical Engineering Conference, Cleveland, OH.

2007, "Dynamic Myocardial Contractile Parameters from Left Ventricular Pressure-Volume Measurements," Invited Speaker, Symposium: "Cardiovascular Function as Studied by Means of In Silico Research," Biomedical Engineering Society Annual Meeting, Los Angeles, CA.

2007, "HDAC4, A Member of Class-II HDAC Family, Binds to MLP and Associates with the Z-Disc and I-Band of Cardiac Muscle Sarcomeres," American Heart Association, 80th Scientific Sessions, Orlando, FL.

2007, "Left Ventricular Function is Depressed In Mice Expressing Constitutively Psuedo-Phosphorylated Cardiac Troponin I," American Heart Association, 80th Scientific Sessions, Orlando, FL.

2007, "Myofilamental Protein Acetylation: A New Regulator of Cardiac Muscle Contraction," Invited Seminar, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA.

2007, "Noninvasive Methods for the Assessment of Cardiovascular Disease," . Invited Talk, Symposium at the American Heart Association Annual Conference, Orlando, FL.

2007, "Regulation of Arterial Gap Junctions by Steady and Pulsatile Perfusion: An Ex Vivo Study," Midwest Biomedical Engineering Conference, Cleveland, OH.

2007, "Role of Dynamic Calcium-Force Relationship in Cardiac Muscle Contraction," Invited Seminar, Department of Physiology, Case Western Reserve University, Cleveland, OH.

2007, "Role of Myofibrillar Protein Acetylation in Regulating Cardiac Muscle Contraction," Invited Seminar, Department of Physiology, Ohio State University, Columbus, OH.

2008, "Application of Multiphase Fluid Dynamics to Vascular Blood Flow," Invited Talk, Symposium at the Federal Food and Drug Administration, Washington, DC.

2008, "Arterial Stiffness, Pulse Wave Velocity, and Cardiovascular Function," Invited Talk, Symposium at the American College of Cardiology Annual Conference, Chicago, IL.

2008, "Left Ventricular Torsion Analysis Using Speckle Tracking In A Canine Model of Left Bundle Branch Block and Cardiac Resynchronization Therapy: Relationship With Cardiac Performance," American Society of Echocardiography Scientific Sessions, Toronto, Canada.

2008, "Protein Kinase C-Induced Troponin I Phosphorylation Causes Changes in Cardiac Contractile Function but not the Intracellular Calcium Transient," American Heart Association, 81st Scientific Sessions, New Orleans, LA.

2008, "Pulsatile Arterial Load and Cardiovascular Function: Facts, Fiction, and Wishful Thinking," Medicine Grand Rounds, Department of Medicine, University of New Mexico, Albuquerque, NM.

2009, "Acetylation of Sarcomeric Proteins Plays a Role in Regulating Cardiac Muscle Contractile Activity," Department of Physiolgy and Functional Genomics, University of Florida, Gainesville, FL.

2009, "Dynamic Intracellular Free Calcium-Pressure Relationships in the Mouse Heart," National Energy Technology Laboratory, Morgantown, WV.

2009, "Relaxin: A Fountain of Vascular Youth?," Center for Vascular remodeling and Regeneration, University of Pittsburgh, Pittsburgh, PA.

2010, "Acetylation of Sarcomeric Proteins Plays a Role in Regulating Cardiac Muscle Contractile Activity," Institute for Medicine and Engineering, University of Pennsylvania, Philadelphia, PA.

2011, "Vascular Stiffness: Independent Cardiovascular Risk Factor and Potential Therapeutic Target?," Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Vermont, Burlington, VT.