Pitt | Swanson Engineering
Vande Geest, Jonathan
Bioengineering Department

PhD in Bioengineering, University of Pittsburgh, 2005

BS in Biomedical Engineering, University of Iowa, 2000

 PhD in Bioengineering, University of Pittsburgh, 2005

 BS in Biomedical Engineering, University of Iowa, 2000

Biomechanics

Constitutive modeling

Extracellular matrix

Finite element modeling

Polymer mechanics

Tissue engineering

Ocular, vascular, and nerve biomechanics, tissue engineering, nonlinear optical microscopy, and finite element modeling

Freytes, D.O., Rundell, A.E., Vande Geest, J., Vorp, D.A., Webster, T.J., and Badylak, S.F., 2005, "Analytically derived material properties of multilaminated extracellular matrix devices using the ball-burst test.," Biomaterials, vol.26, no.27, pp. 5518-31.

Freytes, D.O., Vande Geest, J., Thapa, A., Vorp, D.A., and Badylak, S.F., 2005, "Mechanical Characterization of Native and Esophageal Graft in a Dog Model," Vail, CO.

Vande Geest, J., Bohra, A., Sun, W., Di Martino, E.S., Sacks, M.S., and Vorp, D.A., 2004, "Development and 3D Finite Element Implementation of a Multiaxial Constitutive Relation for Abdominal Aortic Aneurysms (Vol 1) (ISBN 0-7918-4178-2)," ASME IMECE 2004.

 

1. Vande Geest JP, Di Martino ES, Vorp DA*.  “An Analysis of the Complete Strain Field within FlexercellTM Membranes”, Journal of Biomechanics, 2004 Dec;37(12):1923-8. 

2. Vande Geest JP, Sacks MS, Vorp DA*.  “Age Dependency of the Biaxial Biomechanical Behavior of Human Abdominal Aorta”, Journal of Biomechanical Engineering, 2004 Dec:126:815-822.

3. Vorp DA*, Vande Geest JP.  “Biomechanical Determinants of Abdominal Aortic Aneurysm Rupture”, Arteriosclerosis Thrombosis and Vascular Biology, 2005 Aug;25(8):1558-66 (invited review paper).

4. Freytes DO, Rundell AE, Vande Geest JP, Vorp DA, Webster TJ, and Badylak SF*.  “Analytically Derived Material Properties of Multilaminated Extracellular Matrix Devices using the Ball-burst Test”, Biomaterials, 2005 26(27):5518-5531.

5. Vande Geest JP, Sacks MS, Vorp DA*. “The Effects of Aneurysm on the Biaxial Mechanical Behavior of Human Abdominal Aorta”, Journal of Biomechanics, 2006 39(7):1324-1334.

6.Vande Geest JP, Wang DH, Wisniewski SR, Makaroun MS, Vorp DA*.  “Towards a Noninvasive Method for the Determination of Patient-Specific Wall Strength Distribution in Abdominal Aortic Aneurysms”, Annals of Biomedical Engineering, 2006 34(7):1098-1106.

7. Di Martino ES, Bohra A, Vande Geest JP, Gupta N, Makaroun MS, Vorp DA*.  “Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue.”  Journal of Vascular Surgery. 2006 Mar; 43(3):570-576; discussion 576.

8. Vande Geest JP, Sacks MS, Vorp DA*.  “A Planar Biaxial Constitutive Relation for the Luminal Layer of Intraluminal Thrombus in Abdominal Aortic Aneurysms”, Journal of Biomechanics 2006;39(13):2347-54.

9. Vande Geest JP, Dillavou ED, Di Martino ES, Bohra A, Makaroun MS, Vorp DA*, “Gender-related differences in the tensile strength of abdominal aortic aneurysms”, Ann N Y Acad Sci. 2006 Nov; 1085: 400-402 (short paper).

10. Vande Geest JP, DI Martino ES, Bohra A, Makaroun MS, Vorp DA*, “A biomechanics-based rupture potential index for abdominal aortic aneurysm risk assessment: demonstrative application”, Ann N Y Acad Sci. 2006 Nov;1085:11-21 (invited research article).

11. Vande Geest JP*, Simon BR, Mortazavi A+, “Towards a Model for Local Drug Delivery in Abdominal Aortic Aneurysms”, Ann N Y Acad Sci. 2006 Nov; 1085: 396-399 (short paper).

12. Vande Geest JP, Schmidt DE, Sacks MS, Vorp DA*. “The Effects of Anisotropy on the Stress Analyses of Patient-Specific Abdominal Aortic Aneurysms.” Ann Biomed Eng. 2008 Jun;36(6):921-32.

13. Ashton JH+, Vande Geest JP*, Simon BR, Haskett DG, “Compressive Mechanical Properties of the Intraluminal Thrombus in Abdominal Aortic Aneurysms and Fibrin-Based Thrombus Mimics”, Journal of Biomechanics, 2009 Feb 9;42(3):197-201.

14. Junkin M, Watson J+, Vande Geest JP, Wong PK*, “Template-guided Self-Assembly of Colloidal Quantum Dots Using Plasma Lithography”, Advanced Materials, 2009, 21:1-5.

15. Mortazavi A+, Simon BR, Stamer WD, Vande Geest JP* “Drained Secant Modulus for Human and Porcine Peripapillary Sclera Using Unconfined Compression Testing”, Experimental Eye Research, 2009 Dec;89(6):892-7.

16. Keyes JT+, Junkin M, Wong PK, Vande Geest JP*, “Computational Simulation of a Magnetic Microactuator for Tissue Engineering Applications”, Biomedical Microdevices, 2009 Dec;11(6):1259-67.

17. Warren PD+, McGrath DV, Vande Geest JP*, “Effect of Crosslinker Length and Composition on the Hydrophobicity and Thermomechanical Response of Acrylate-based Shape Memory Polymers”, Macromolecular Materials and Engineering, 2010 295:386-396. 

18. Layman R+, Missoum S*,Vande Geest JP, “Simulation and Probabilistic Failure Prediction of Grafts for Aortic Aneurysm”, Engineering Computations, 2010; 27(1):84–105.

19. Ayyalasomayajula, A+, Polk A+, Basudhar A, Missoum S, Nissim L, Vande Geest JP*, “Three Dimensional Active Contours for Reconstruction of Abdominal Aortic Aneurysms, Annals of Biomedical Engineering, 2010 Jan;38(1):164-76.

20. Haskett DG+, Johnson G+, Zhou A+, Utzinger U, Vande Geest JP*, “Microstructural and biomechanical alterations of the human aorta as a function of age and location”, Biomechanics and Modeling in Mechanobiology, 2010 Dec; 9(6):725-36.

21. Alexander MJ+, Barkmeier-Kraemer J, Vande Geest JP*, “Biomechanical Response of Recurrent Laryngeal Nerve in the Piglet”, Annals of Biomedical Engineering, 2010 Aug; 38(8):2553-62. 

22. Ayyalasomayajula A+, Simon BR,Vande Geest JP*, “Porohyperelastic Finite Element Modeling of Abdominal Aortic Aneurysms”, Journal of Biomechanical Engineering, 2010 Oct;132(10):104502

23. Vad S+, Eskinazi A+, Corbett T, McGloughlin T, Vande Geest JP*, “Coefficient of Friction of Endovascular Stent Grafts”, Journal of Biomechanical Engineering, 2010 Dec; 132(12):121007. 

24. Yan D+, McPheeters S+, Johnson G+, Utzinger U, Vande Geest JP*, “Microstructural organization of the human posterior sclera as a function of age and ethnicity”, Investigative Ophthalmology and Visual Science, 2011 Feb; 52(2):821-829. 

25. Ashton JH+, Mertz JA+, Harper JL+, Slepian MJ, Mills JL, McGrath DV, Vande Geest JP*, “Polymeric endoaortic paving: Mechanical, thermoforming, and degradation properties of polycaprolactone/polyurethane blends for cardiovascular applications”, Acta Biomaterialia, 2011 Jan; 7(1):287-94. 

26. Keyes JT+, Borowicz SM+, Rader JH+, Utzinger U, Azhar M, Vande Geest JP*, “Design and demonstration of a microbiaxial optomechanical device for multi-scale characterization of soft biological tissues”, Microscopy and Microanalysis, 2011 Jan; 13:1-9.

27. Vande Geest JP*, Newberg T, Rigby PR, Simon BR, “Coupled porohyperelastic mass transport (PHEXPT) finite element models for soft tissues using ABAQUS”, J. Biomechanical Engineering. 2011 133(4):044502 

28. Ashton JH+, Ayyalasomayajula A+,Vande Geest JP*, “Wall stress reduction in AAA as a result of polymeric endoaortic paving”, Annals of Biomedical Engineering, 2011 Jun 39(6):1680-1690. 

29. Keyes JT+, Utzinger U., Vande Geest JP*,  “Adaptation of a Two-Photon-Microscope-Interfacing Planar Biaxial Testing Device for the Microstructural and Macroscopic Characterization of Small Tubular Tissue Specimens”, Journal of Biomechanical Engineering, 2011 Jul;133(7):075001. 

30. Keyes JT+, Yan DM+,Vande Geest JP*, “A gimbal-mounted pressurization chamber for macroscopic and microscopic assessment of ocular tissues”, Journal of Biomechanical Engineering, 2011 Sep;133(9):095001.

31. Haskett D+, Speicher E+, Fouts M, Larson D, Azhar M, Utzinger U, Vande Geest JP*, “The effects of angiotensin II on the coupled microstructural and biomechanical response of C57BL/6 mouse aorta”, Journal of Biomechanics, 2012 45(5):772-9.

32. Haskett DG+, Doyle JJ, Gard C, Chen H, Ball C, Estabrook MA, Encinas AC, Dietz HC, Utzinger U, Vande Geest JP, Azhar M*, “Altered tissue behavior of non-aneurysmal descending thoracic aorta in the mouse model of marfan syndrome”, Cell and Tissue Research, 2012 Jan; 347(1):267-77.

33. Keyes JT+, Lockwood D, Simon BR, Vande Geest JP*, “Deformationally dependent fluid transport properties of porcine coronary arteries based on location in the coronary vasculature”, Journal of the Mechanical Behavior of Biomedical Materials, 2013 Jan; 17:296-306.

34. Keyes JT+, Lockwood DR, Utzinger U, Montilla L, Witte RS, Vande Geest JP*, “Comparisons of planar and tubular biaxial tensile testing protocols of the same porcine coronary arteries”, Annals of Biomedical Engineering, special issue in cardiovascular mechanics, 2013, 41(7): 1579-1591. 

35. Keyes JT+, Lockwood D, Simon BR, Vande Geest JP*, “Location dependent coronary artery diffusive and convective mass transport properties of a lipophilic drug surrogate measured using nonlinear microscopy”, Pharmaceutical Research, 2013 Apr; 30(4):1147-1160. 

36. Warren PD+, Sycks DG, McGrath DV, Vande Geest JP*, “Modeling the microstructurally dependent mechanical properties of poly (ester-urethane-urea)s”, Journal of Biomedical Materials Research: Part A, 2013, 101(12):3382-3387.

37. Keyes JT+, Lockwood D, Simon BR, Vande Geest JP*, “A finite element study on variations in drug transport in stented porcine coronary arteries based on location in the coronary arterial tree”, Journal of Biomechanical Engineering, 2013 Jun 1; 135(6):61009-11.

38. Haskett DG+, Azhar M, Utzinger U, Vande Geest JP*, “Progressive alterations in microstructural organization and biomechanical response in the apoE mouse model of aneurysm”, Biomatter. 2013 Apr 1;3(3):e24648-1 to e24648-10.

39. Danford FL+, Yan D+, Dreier RA+, Cahir TM+, Girkin CA, Vande Geest JP*, “Differences in the region and depth-dependent microstructural organization in normal versus glaucomatous human posterior sclerae”, Investigative Ophthalmology and Visual Science, 2013 December 54(13):7922-7932.

40. Harper JL+, Simon BR, Vande Geest JP*, “A one dimensional mixed porohyperelastic transport swelling finite element model with growth”, Journal of the Mechanical Behavior of Biomedical Materials, 2014, 29:663-675.

41. Pyne J+, Ayyalasomayajula A+, Danford FL+, Vande Geest JP*, “Sequential digital image correlation for the mapping of posterior ocular strains”, Journal of Biomechanical Engineering Feb 2014, 136:021002-1 – 021002-12.

42. Williams, MJ+, Utzinger U, Barkmeier-Kraemer J, Vande Geest JP*, “Differences in the microstructure and biomechanical properties of the recurrent laryngeal nerve as a function of age and location”, accepted in the Journal of Biomechanical Engineering, Aug 2014, 136(8):081008.

43. Ardila DC+, Tamimi E+, Danford FL+, Haskett DG+, Kellar RS, Doetschman T, Vande Geest JP*, “TGFβ2 differentially modulates smooth muscle cell proliferation and migration in electrospun gelatin-fibrinogen constructs”, Biomaterials Jan. 2015, 37:164-173.

44. Williams MJ+, Ayyalasomayajula A+, Behkam R+, Bierhals AJ, Jacobs ME, Edgar JD, Paniello RC, Barkmeier-Kraemer JM, Vande Geest JP*, “A computational study of the role of the aortic arch in idiopathic unilateral vocal fold paralysis”, The Journal of Applied Physiology, 2015 Feb 15;118(4):465-74

45. Ayyalasomayajula A+, Park RI, Simon BR, Vande Geest JP*, “A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics”, Computer Methods in Biomechanics and Biomedical Engineering, 2015 Jul 21:1-12. 

46. Tamimi E+, Ardila DC+, Haskett DG+, Doetschman T, Slepian MJ, Kellar RS, Vande Geest JP, “The effect of cross linking time on the tubular biaxial mechanical properties of electrospun gelatin/fibrinogen vascular constructs”, Journal of Biomechanical Engineering, 2016 Jan 138(1):011001-1 – 011001-12.

47. Harrison S+, Tamimi E+, Uhlorn J+, Vande Geest JP, “Computationally optimizing the compliance of a biopolymer based tissue engineered vascular graft”, Journal of Biomechanical Engineering, 2016 Jan 138(1):014505-1 – 014505-5.

48. Haskett DG+, David Maestas, Stephen Howerton, Smith T+, Ardila DC+, Doetschman T, Utzinger U, McGrath D, McIntyre O, Vande Geest JP*,  “2-Photon characterization of optical proteolytic beacons for imaging changes in MMP activity in a mouse model of aneurysm”, accepted in Microscopy and Microanalysis 2016 Feb 23:1-12.

49. Armstrong MH+, Buganza A, Kuhl E, Simon BR, Vande Geest JP*,  “A finite element model for mixed porohyperelasticity with transport, swelling, and growth”, accepted in PLoS One 2016 Apr 14;11(4):e0152806.